S. Cherian

发表

Potent and orally bioavailable noncysteine-containing inhibitors of protein farnesyltransferase.

S. Ng, D. Augeri, P. Kovar, 1999, Bioorganic & medicinal chemistry letters.

Effect of novel CAAX peptidomimetic farnesyltransferase inhibitor on angiogenesis in vitro and in vivo.

S. Ng, S. Rosenberg, J. Leal, 1999, European journal of cancer.

Inhibition of farnesyltransferase with A-176120, a novel and potent farnesyl pyrophosphate analogue.

S. Ng, P. Kovar, S. Rosenberg, 2000, European journal of cancer.

Potent inhibitors of protein farnesyltransferase: heteroarenes as cysteine replacements.

S. Ng, P. Kovar, S. Rosenberg, 1999, Bioorganic & medicinal chemistry letters.

In vitro transcription/translation assay for the screening of hMLH1 and hMSH2 mutations in familial colon cancer.

Sajeev P. Cherian, M. Hawn, L. Kam-Morgan, 1995, Gastroenterology.

Discovery of a series of cyclohexylethylamine-containing protein farnesyltransferase inhibitors exhibiting potent cellular activity.

S. Ng, S. Rosenberg, H. Sham, 1999, Journal of medicinal chemistry.

Human chromosome 3 corrects mismatch repair deficiency and microsatellite instability and reduces N-methyl-N'-nitro-N-nitrosoguanidine tolerance in colon tumor cells with homozygous hMLH1 mutation.

Sajeev P. Cherian, T. Kunkel, C. Boland, 1994, Cancer research.

Microsatellite instability in nonneoplastic mucosa from patients with chronic ulcerative colitis.

Sajeev P. Cherian, C. Boland, M. Bronner, 1996, Cancer research.

Modulation of drug resistance by α-tubulin in paclitaxel-resistant human lung cancer cell lines

S. Ng, S. Rosenberg, R. B. Credo, 2000 .

Modulation of paclitaxel resistance by annexin IV in human cancer cell lines

N. Collins, S. Ng, S. Tahir, 2000, British Journal of Cancer.

Potent and selective non-cysteine-containing inhibitors of protein farnesyltransferase.

S. Ng, D. Augeri, S. Rosenberg, 1998, Journal of medicinal chemistry.

Second-generation peptidomimetic inhibitors of protein farnesyltransferase demonstrating improved cellular potency and significant in vivo efficacy.

S. Ng, P. Kovar, S. Rosenberg, 1999, Journal of medicinal chemistry.