Manorama M. Patel

发表

RATIONAL DESIGN OF POTENT CARBOXYLIC ACID BASED BISUBSTRATE INHIBITORS OF RAS FARNESYL PROTEIN TRANSFERASE

S. Robinson, D. Patel, L. Hunihan, 1994 .

Phenol based tripeptide inhibitors of ras farnesyl protein transferase

E. Gordon, D. Patel, Manorama M. Patel, 1994 .

Aglycone exploration of C-arylglucoside inhibitors of renal sodium-dependent glucose transporter SGLT2.

W. Humphreys, T. Waldron, Songping Han, 2008, Bioorganic & medicinal chemistry letters.

C-Arylglucoside synthesis: triisopropylsilane as a selective reagent for the reduction of an anomeric C-phenyl ketal

A. Doyle, W. Meng, B. Ellsworth, 2003 .

Discovery of dapagliflozin: a potent, selective renal sodium-dependent glucose cotransporter 2 (SGLT2) inhibitor for the treatment of type 2 diabetes.

W. Humphreys, O. Flint, E. Janovitz, 2008, Journal of medicinal chemistry.

Thromboxane receptor antagonist BMS-180291: A new pre-clinical lead

J. Barrish, P. Sprague, R. Morrison, 1992 .

A Mild Procedure for the Preparation of 2-Oxazolines

Manorama M. Patel, David M. Roush, 1985 .

Potent and selective biphenyl azole inhibitors of adipocyte fatty acid binding protein (aFABP).

David S. Taylor, R. Parker, R. Stoffel, 2007, Bioorganic & medicinal chemistry letters.

Discovery of (R)-7-cyano-2,3,4, 5-tetrahydro-1-(1H-imidazol-4-ylmethyl)-3- (phenylmethyl)-4-(2-thienylsulfonyl)-1H-1,4-benzodiazepine (BMS-214662), a farnesyltransferase inhibitor with potent preclinical antitumor activity.

S. Chong, J. Hunt, Soong-Hoon Kim, 2000, Journal of medicinal chemistry.

Development of highly potent inhibitors of Ras farnesyltransferase possessing cellular and in vivo activity.

M. Barbacid, B. Seizinger, J. Hunt, 1996, Journal of medicinal chemistry.