Stanton F. McHardy

发表

Infection Screening in Biofluids with Glucose Test Strips.

W. Gorski, Michael Bekhit, Hua-Yu L. Wang, 2020, Analytical chemistry.

Recent progress in the development of small molecule Nrf2 modulators: a patent review (2012-2016)

F. Feng, Kai Gu, Haopeng Sun, 2017, Expert opinion on therapeutic patents.

18F‐FDG microPET imaging detects early transient response to an IGF1R inhibitor in genetically engineered rhabdomyosarcoma models

C. Keller, J. Michalek, D. Hawkins, 2012, Pediatric blood & cancer.

The novel capsazepine analog, CIDD‐99, significantly inhibits oral squamous cell carcinoma in vivo through a TRPV1‐independent induction of ER stress, mitochondrial dysfunction, and apoptosis

H. Mcguff, M. Hart, Stanton F. McHardy, 2019, Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology.

Targeting Candida albicans filamentation for antifungal drug development

J. Lopez-Ribot, S. Saville, C. Pierce, 2017, Virulence.

Recent advances in acetylcholinesterase Inhibitors and Reactivators: an update on the patent literature (2012-2015)

Hua-Yu L. Wang, Stanton F. McHardy, Shelby V McCowen, 2017, Expert opinion on therapeutic patents.

Structure-Activity Relationship for Small Molecule Inhibitors of Nicotinamide N-Methyltransferase.

S. Watowich, Virginia Vance, Jonathan D. Hommel, 2017, Journal of medicinal chemistry.

A modular PROTAC design for target destruction using a degradation signal based on a single amino acid

T. Luo, Hai Rao, Stanton F. McHardy, 2019, The Journal of Biological Chemistry.

Tamoxifen Derivatives Alter Retromer-Dependent Endosomal Tubulation and Sorting to Block Retrograde Trafficking of Shiga Toxins

Andrey S Selyunin, S. Mukhopadhyay, Stanton F. McHardy, 2021, Toxins.

A novel small molecule inhibitor of Candida albicans biofilm formation, filamentation and virulence with low potential for the development of resistance

J. Lopez-Ribot, S. Saville, A. Lazzell, 2015, npj Biofilms and Microbiomes.

Design, Synthesis, and Characterization of Novel Small Molecules as Broad Range Antischistosomal Agents.

P. Hart, Alexander B. Taylor, Frédéric D. Chevalier, 2018, ACS medicinal chemistry letters.

Discovery of CP-866,087, a mu opioid receptor antagonist for the treatment of alcohol abuse and dependence

Anne W. Schmidt, N. Grahame, S. Liras, 2011 .

Inhibition of Ca2+ entry by capsazepine analog CIDD-99 prevents oral squamous carcinoma cell proliferation

Yuyang Sun, Brij B. Singh, Stanton F. McHardy, 2022, Frontiers in Physiology.

Reductive cleavage of NO bonds in hydroxylamines and hydroxamic acid derivatives using samarium diiodide

Travis T Wager, G. E. Keck, Stanton F. McHardy, 1999 .

Biaryl piperidines as potent and selective delta opioid receptor ligands.

Anne W. Schmidt, S. Liras, Ernesto Callegari, 2010, Bioorganic & medicinal chemistry letters.

Some unusual reactions of weinreb amides

G. E. Keck, Stanton F. McHardy, J. Murry, 1993 .

TOTAL SYNTHESIS OF (+)-7-DEOXYPANCRATISTATIN : A RADICAL CYCLIZATION APPROACH

G. E. Keck, Stanton F. McHardy, J. Murry, 1995 .

Reductive cleavage of NO bonds in hydroxylamine and hydroxamic acid derivatives using SmI2/THF

Travis T Wager, G. E. Keck, Stanton F. McHardy, 1995 .

Total Synthesis of (+)-Carbonolide B

A. Palani, G. E. Keck, Stanton F. McHardy, 1994 .

Structure-Activity Relationships of New Natural Product-Based Diaryloxazoles with Selective Activity against Androgen Receptor-Positive Breast Cancer Cells.

Andrew J. Robles, R. Cichewicz, S. Cai, 2017, Journal of medicinal chemistry.

DIASTEREOSELECTIVE 6-EXO RADICAL CYCLIZATIONS OF OXIME ETHERS : TOTAL SYNTHESIS OF 7-DEOXYPANCRATISTATIN

G. E. Keck, Stanton F. McHardy, J. Murry, 1999 .

A Second-Generation Radical-Based Synthesis of (+)-7-Deoxypancratistatin†

Travis T Wager, G. E. Keck, Stanton F. McHardy, 1998 .

Reductive Cleavage of N—O Bonds in Hydroxylamines and Hydroxamic Acid Derivatives Using Samarium Diiodide.

Travis T Wager, G. E. Keck, Stanton F. McHardy, 2000 .

Rational approach to drug discovery for human schistosomiasis

Alexander B. Taylor, Frédéric D. Chevalier, T. Anderson, 2021, International journal for parasitology. Drugs and drug resistance.

An iterative process produces oxamniquine derivatives that kill the major species of schistosomes infecting humans

Alexander B. Taylor, Frédéric D. Chevalier, T. Anderson, 2020, PLoS neglected tropical diseases.

Molecular Basis for Hycanthone Drug Action in Schistosome Parasites.

Alexander B. Taylor, P. LoVerde, Xiaohang Cao, 2020, Molecular and biochemical parasitology.

Why does oxamniquine kill Schistosoma mansoni and not S. haematobium and S. japonicum?

P. Hart, Alexander B. Taylor, Frédéric D. Chevalier, 2020, International journal for parasitology. Drugs and drug resistance.

Diabetic strips as coulometric sensors for hydroquinone and leukocyte esterase

W. Gorski, Michael Bekhit, Hua-Yu L. Wang, 2020 .

Synthesis and Characterization of Pyridine Compounds for Amperometric Measurements of Leukocyte Esterase

W. Gorski, Stanton F. McHardy, T. Menard, 2018, Chembiochem : a European journal of chemical biology.

Electrochemical Substrate and Assay for Esterolytic Activity of Human White Blood Cells.

W. Gorski, A. Fleischman, Stanton F. McHardy, 2017, Analytical chemistry.

Selective and membrane‐permeable small molecule inhibitors of nicotinamide N‐methyltransferase reverse high fat diet‐induced obesity in mice

S. Watowich, C. Finnerty, Virginia Vance, 2018, Biochemical Pharmacology.

Development of Anti-Virulence Approaches for Candidiasis via a Novel Series of Small-Molecule Inhibitors of Candida albicans Filamentation

J. Lopez-Ribot, S. Saville, A. Lazzell, 2017, mBio.

Structural and enzymatic insights into species-specific resistance to schistosome parasite drug therapy

P. Hart, Alexander B. Taylor, N. Clark, 2017, The Journal of Biological Chemistry.

Novel Small-Molecule Inhibitors of Protein Kinase C Epsilon Reduce Ethanol Consumption in Mice

M. Roberto, Jingyi Wang, Dan Wang, 2017, Biological Psychiatry.

Small molecule nicotinamide N‐methyltransferase inhibitor activates senescent muscle stem cells and improves regenerative capacity of aged skeletal muscle

Ted G. Graber, S. Watowich, J. Papaconstantinou, 2019, Biochemical pharmacology.

Tamoxifen blocks retrograde trafficking of Shiga toxin 1 and 2 and protects against lethal toxicosis

Andrey S Selyunin, S. Mukhopadhyay, Stanton F. McHardy, 2019, Life Science Alliance.

Histone deacetylase inhibitors enhance estrogen receptor beta expression and augment agonist-mediated tumor suppression in glioblastoma

A. Brenner, R. Tekmal, R. Vadlamudi, 2021, Neuro-oncology advances.

Discovery and pharmacological characterization of a selective delta opiate receptor antagonist (CP-646,777)

Anne W. Schmidt, S. Liras, Ernesto Callegari, 2011 .

Addressing the oxamniquine in vitro-in vivo paradox to facilitate a new generation of anti-schistosome treatments

M. Cameron, P. LoVerde, Susan Khan, 2023, International journal for parasitology. Drugs and drug resistance.

1,3‐propanediol binds deep inside the channel to inhibit water permeation through aquaporins

Liao Y. Chen, C. Yeh, Lili Yu, 2015, Protein science : a publication of the Protein Society.

Oxamniquine derivatives overcome Praziquantel treatment limitations for Schistosomiasis

P. LoVerde, Stanton F. McHardy, Jayce Rhodes, 2023, bioRxiv.

Schistosome Sulfotransferases: Mode of Action, Expression and Localization

J. Collins, Frédéric D. Chevalier, T. Anderson, 2022, Pharmaceutics.

A novel small molecule PKC epsilon inhibitor reduces hyperalgesia induced by paclitaxel or opioid withdrawal

M. Marinelli, J. Levine, R. Messing, 2023, bioRxiv.

A novel catalytic heme cofactor in SfmD with a single thioether bond and a bis-His ligand set revealed by a de novo crystal structural and spectroscopic study†

I. Shin, Stanton F. McHardy, Aimin Liu, 2021, Chemical science.

Total Synthesis of (+)‐7‐Deoxypancratistatin: A Radical Cyclization Approach.

G. E. Keck, Stanton F. McHardy, J. Murry, 1995 .

Design, synthesis, and characterization of novel, nonquaternary reactivators of GF-inhibited human acetylcholinesterase.

P. M. Thompson, Michael W Tidwell, William Bauta, 2014, Bioorganic & Medicinal Chemistry Letters.

Modulation of α1β3γ2 GABAA receptors expressed in X. laevis oocytes using a propofol photoswitch tethered to the transmembrane helix

E. Bertaccini, J. Trudell, R. Harris, 2021, Proceedings of the National Academy of Sciences of the United States of America.

Synthesis and SAR of novel capsazepine analogs with significant anti-cancer effects in multiple cancer types.

M. Hart, Stanton F. McHardy, S. Polusani, 2019, Bioorganic & Medicinal Chemistry.

Synthesis and Characterization of Pyridine Compounds for Amperometric Measurements of Leukocyte Esterase

W. Gorski, Stanton F. McHardy, T. Menard, 2018, Chembiochem : a European journal of chemical biology.

Tyrosine phosphorylation regulates ERβ ubiquitination, protein turnover, and inhibition of breast cancer

Huai-Chin Chiang, T. Curiel, R. Elledge, 2016, Oncotarget.

Noncoupled Fluorescent Assay for Direct Real-Time Monitoring of Nicotinamide N-Methyltransferase Activity.

S. Watowich, Virginia Vance, H. Neelakantan, 2017, Biochemistry.

Molecular dynamics study of human carbonic anhydrase II in complex with Zn(2+) and acetazolamide on the basis of all-atom force field simulations.

Liao Y. Chen, A. Tsin, Stanton F. McHardy, 2016, Biophysical chemistry.

Oxamniquine derivatives overcome Praziquantel treatment limitations for Schistosomiasis

P. LoVerde, Stanton F. McHardy, Jayce Rhodes, 2023, PLoS pathogens.