Seema M. Nathwani

发表

Synthesis and Biological Evaluation of 1-(Diarylmethyl)-1H-1,2,4-triazoles and 1-(Diarylmethyl)-1H-imidazoles as a Novel Class of Anti-Mitotic Agent for Activity in Breast Cancer

D. Zisterer, M. Meegan, D. Endringer, 2021, Pharmaceuticals.

Antitumor effect of pyrrolo-1,5-benzoxazepine-15 and its synergistic effect with Oxaliplatin and 5-FU in colorectal cancer cells

S. Gemma, G. Campiani, S. Butini, 2016, Cancer biology & therapy.

PBOX-15 induces apoptosis and improves the efficacy of oxaliplatin in human colorectal cancer cell lines.

S. Gemma, G. Campiani, S. Butini, 2013, European journal of pharmacology.

Novel microtubule-targeting agents, pyrrolo-1,5-benzoxazepines, induce apoptosis in multi-drug-resistant cancer cells

G. Campiani, D. Williams, D. Zisterer, 2010, Cancer Chemotherapy and Pharmacology.

Development of novel cyclic peptides as pro-apoptotic agents.

E. Novellino, P. Campiglia, Simone Brogi, 2016, European journal of medicinal chemistry.

Synthesis and evaluation of azetidinone analogues of combretastatin A-4 as tubulin targeting agents.

D. Zisterer, L. Greene, M. Meegan, 2010, Journal of medicinal chemistry.

Piperlongumine (piplartine) and analogues: Antiproliferative microtubule-destabilising agents.

D. Zisterer, M. Meegan, N. O’Boyle, 2017, European journal of medicinal chemistry.

The pyrrolo-1,5-benzoxazepine, PBOX-15, enhances TRAIL-induced apoptosis by upregulation of DR5 and downregulation of core cell survival proteins in acute lymphoblastic leukaemia cells

G. Campiani, S. Butini, D. Williams, 2016, International journal of oncology.

β-Lactam analogues of combretastatin A-4 prevent metabolic inactivation by glucuronidation in chemoresistant HT-29 colon cancer cells.

D. Zisterer, L. Greene, M. Meegan, 2017, European journal of medicinal chemistry.

Non-nucleoside inhibitors of human adenosine kinase: synthesis, molecular modeling, and biological studies.

E. Novellino, F. Da Settimo, C. La Motta, 2011, Journal of medicinal chemistry.

β-Lactams with antiproliferative and antiapoptotic activity in breast and chemoresistant colon cancer cells.

Darren Fayne, Fiona O'Connell, Mary J Meegan, 2020, European journal of medicinal chemistry.

Synthesis and Biochemical Evaluation of 3-Phenoxy-1,4-diarylazetidin-2-ones as Tubulin-Targeting Antitumor Agents.

Thomas F. Greene, D. Zisterer, L. Greene, 2016, Journal of medicinal chemistry.

Synthesis and Antiproliferative Evaluation of 3-Chloroazetidin-2-ones with Antimitotic Activity: Heterocyclic Bridged Analogues of Combretastatin A-4

Thomas F. Greene, D. Zisterer, M. Meegan, 2021, Pharmaceuticals.

Isouronium and N-hydroxyguanidinium derivatives as Cell growth inhibitors: A comparative study.

D. Zisterer, I. Rozas, Seema M. Nathwani, 2016, European journal of medicinal chemistry.

β-Lactam estrogen receptor antagonists and a dual-targeting estrogen receptor/tubulin ligand.

Andrew J. S. Knox, Shu Wang, Andrew J S Knox, 2014, Journal of medicinal chemistry.

Synthesis and evaluation of antiproliferative microtubule-destabilising combretastatin A-4 piperazine conjugates.

D. Zisterer, M. Meegan, N. O’Boyle, 2019, Organic & biomolecular chemistry.

3-Vinylazetidin-2-Ones: Synthesis, Antiproliferative and Tubulin Destabilizing Activity in MCF-7 and MDA-MB-231 Breast Cancer Cells

Thomas F. Greene, D. Zisterer, M. Meegan, 2019, Pharmaceuticals.

Novel cis-restricted β-lactam combretastatin A-4 analogues display anti-vascular and anti-metastatic properties in vitro.

L. Hughes, D. Zisterer, S. Mcdonnell, 2013, Oncology reports.

Design and synthesis of multifunctional microtubule targeting agents endowed with dual pro-apoptotic and anti-autophagic efficacy.

L. Altucci, D. Lucena‐Agell, J. Díaz, 2022, European journal of medicinal chemistry.

Aromatic bis-N-hydroxyguanidinium derivatives: synthesis, biophysical, and biochemical evaluations.

D. Zisterer, Amila Kahvedžić, I. Rozas, 2013, Journal of medicinal chemistry.

The Vascular Targeting Agent Combretastatin-A4 and a Novel cis-Restricted β-Lactam Analogue, CA-432, Induce Apoptosis in Human Chronic Myeloid Leukemia Cells and Ex Vivo Patient Samples Including Those Displaying Multidrug Resistance

D. Zisterer, L. Greene, M. Meegan, 2010, Journal of Pharmacology and Experimental Therapeutics.

Involvement of NF-κB in mediating the anti-tumour effects of combretastatins in T cells

D. Zisterer, L. Greene, M. Meegan, 2018, Investigational New Drugs.

Novel microtubule-targeting agents, pyrrolo-1,5-benzoxazepines, induce cell cycle arrest and apoptosis in prostate cancer cells.

G. Campiani, D. Williams, D. Zisterer, 2010, Oncology reports.

Dual targeting of tumour cells and host endothelial cells by novel microtubule-targeting agents, pyrrolo-1,5-benzoxazepines

G. Campiani, D. Williams, D. Zisterer, 2009, Cancer Chemotherapy and Pharmacology.

Antiproliferative and Tubulin-Destabilising Effects of 3-(Prop-1-en-2-yl)azetidin-2-Ones and Related Compounds in MCF-7 and MDA-MB-231 Breast Cancer Cells

Thomas F. Greene, D. Zisterer, M. Meegan, 2023, Pharmaceuticals.

Inhibition of γ-secretase activity synergistically enhances tumour necrosis factor-related apoptosis-inducing ligand induced apoptosis in T-cell acute lymphoblastic leukemia cells via upregulation of death receptor 5.

D. Zisterer, L. Greene, Seema M. Nathwani, 2016, Oncology letters.

Antitumor effect of pyrrolo-1,5-benzoxazepine-15 and its synergistic effect with Oxaliplatin and 5-FU in colorectal cancer cells

S. Gemma, G. Campiani, S. Butini, 2016, Cancer biology & therapy.