J. Joseph

发表

Optimization of an indazole series of selective estrogen receptor degraders: Tumor regression in a tamoxifen-resistant breast cancer xenograft.

Andiliy G. Lai, B. Darimont, J. Sensintaffar, 2015, Bioorganic & medicinal chemistry letters.

Pharmacological Targeting of the Mitochondrial Phosphatase PTPMT1

J. Dixon, P. Casey, D. Pagliarini, 2010, Journal of Pharmacology and Experimental Therapeutics.

Development of antiandrogen ARN-509 1 ARN-509 : a novel antiandrogen for prostate cancer treatment

E. Stanchina, H. Scher, V. Arora, 2012 .

T11 Expression Is Induced by Estrogen-Related Receptor α β-Catenin and Acts in an Autocrine Manner to R ease Cancer Cell Migration

M. Eaton, Ching-Yi Chang, J. Joseph, 2010 .

Differential presentation of protein interaction surfaces on the androgen receptor defines the pharmacological actions of bound ligands.

T. Willson, X. Deng, E. Anderson, 2009, Chemistry & biology.

Identification and Characterization of Two Ca2+/CaM-dependent Protein Kinases Required for Normal Nuclear Division in Aspergillus nidulans *

A. Means, J. Joseph, 2000, The Journal of Biological Chemistry.

Molecular cloning and characterization of Aspergillus nidulans cyclophilin B.

J. Heitman, A. Means, J Heitman, 1999, Fungal genetics and biology : FG & B.

Selective estrogen receptor degraders with novel structural motifs induce regression in a tamoxifen-resistant breast cancer xenograft.

Andiliy G. Lai, B. Darimont, J. Sensintaffar, 2019, Bioorganic & medicinal chemistry letters.

Development of anti-androgen ARN-509 1 ARN-509: a novel anti-androgen for prostate cancer treatment

H. Scher, V. Arora, C. Sawyers, 2012 .

WNT11 Expression Is Induced by Estrogen-Related Receptor α and β -Catenin and Acts in an Autocrine Manner to Increase Cancer Cell Migration

M. Eaton, Ching-Yi Chang, J. Joseph, 2010 .

The peptidyl-prolyl isomerase Pin1.

Winkler, Elisabeth S Yeh, A. Means, 2003, Progress in cell cycle research.

Calcium Binding Is Required for Calmodulin Function in Aspergillus nidulans

A. Means, J. Joseph, James D. Joseph, 2002, Eukaryotic Cell.

Aspergillus nidulans Function in Calcium Binding Is Required for Calmodulin

A. Means, J. Joseph, 2001 .

ARN-509: a novel antiandrogen for prostate cancer treatment.

H. Scher, V. Arora, C. Sawyers, 2012, Cancer research.

The homeodomain protein HOXB13 regulates the cellular response to androgens.

D. McDonnell, Ching-Yi Chang, Bryan M. Wittmann, 2009, Molecular cell.

A clinically relevant androgen receptor mutation confers resistance to second-generation antiandrogens enzalutamide and ARN-509.

Gang Shao, B. Darimont, J. Sensintaffar, 2013, Cancer discovery.

WNT11 expression is induced by estrogen-related receptor alpha and beta-catenin and acts in an autocrine manner to increase cancer cell migration.

M. Dwyer, M. Eaton, D. Kazmin, 2010, Cancer research.

Antitumor Activity of RXDX-105 in Multiple Cancer Types with RET Rearrangements or Mutations

M. Ladanyi, A. Drilon, Shunqi Yan, 2016, Clinical Cancer Research.

WNT11 expression is induced by ERR α and β -catenin and acts in an autocrine manner to increase cancer cell migration

M. Dwyer, M. Eaton, D. Kazmin, 2010 .

Cancer esearch apeutics , Targets , and Chemical Biology T 11 Expression Is Induced by Estrogen-Related Receptor α β-Catenin and Acts in an Autocrine Manner to R ease Cancer Cell Migration

M. Eaton, J. Joseph, H. Wade, 2010 .

Induction of Kruppel-like factor 5 expression by androgens results in increased CXCR4-dependent migration of prostate cancer cells in vitro.

Qianben Wang, D. McDonnell, D. Frigo, 2009, Molecular endocrinology.

Proteomic Analysis of Calcium/Calmodulin-dependent Protein Kinase I and IV in Vitro Substrates Reveals Distinct Catalytic Preferences* 210

T. Haystead, A. Means, C. Kane, 2003, The Journal of Biological Chemistry.

Inhibition of prostate cancer cell growth by second-site androgen receptor antagonists

M. Dwyer, D. McDonnell, Bryan M. Wittmann, 2009, Proceedings of the National Academy of Sciences.

The selective estrogen receptor downregulator GDC-0810 is efficacious in diverse models of ER+ breast cancer

K. Walter, Andiliy G. Lai, J. Giltnane, 2016, eLife.

An Interdomain Interaction of the Androgen Receptor Is Required for Its Aggregation and Toxicity in Spinal and Bulbar Muscular Atrophy*

E. Wilson, D. Merry, H. Montie, 2010, The Journal of Biological Chemistry.

in Vitro Increased CXCR4-Dependent Migration of Prostate Cancer Cells Induction of Krüppel-Like Factor 5 Expression by Androgens Results in

Qianben Wang, D. McDonnell, D. Frigo, 2009 .

Pcp1p, an Spc110p-related calmodulin target at the centrosome of the fission yeast Schizosaccharomyces pombe.

T. Davis, A. Means, M. Morphew, 2002, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

Pcp 1 p , an Spc 110 p-related Calmodulin Target at the Centrosome of the Fission Yeast Schizosaccharomyces pombe 1

T. Davis, A. Means, M. Morphew, 2002 .

Identification of GDC-0810 (ARN-810), an Orally Bioavailable Selective Estrogen Receptor Degrader (SERD) that Demonstrates Robust Activity in Tamoxifen-Resistant Breast Cancer Xenografts.

Andiliy G. Lai, B. Darimont, J. Sensintaffar, 2015, Journal of medicinal chemistry.

Maximizing ER-α Degradation Maximizes Activity in a Tamoxifen-Resistant Breast Cancer Model: Identification of GDC-0927.

Andiliy G. Lai, B. Darimont, J. Sensintaffar, 2018, ACS medicinal chemistry letters.

PINA Is Essential for Growth and Positively Influences NIMA Function in Aspergillus nidulans*

A. Means, J. Joseph, S. Daigle, 2004, Journal of Biological Chemistry.

Identification of an Orally Bioavailable Chromene-Based Selective Estrogen Receptor Degrader (SERD) That Demonstrates Robust Activity in a Model of Tamoxifen-Resistant Breast Cancer.

Andiliy G. Lai, B. Darimont, J. Sensintaffar, 2018, Journal of medicinal chemistry.

Abstract 1943: PARG inhibitors exhibit synthetic lethality with XRCC1 deficiency and a cellular mechanism of action that is distinct from PARP inhibition

Kedar S Vaidya, M. P. Dillon, M. Fischer, 2018, Experimental and Molecular Therapeutics.

Abstract 1648: Discovery and evolution of orally bioavailable selective estrogen receptor degraders for ER+ breast cancer: From GDC-0810 to GDC-0927

Jun Liang, A. Daemen, Andiliy G. Lai, 2018, Cancer Chemistry.

Catalytic Activity Is Required for Calcium/Calmodulin-dependent Protein Kinase IV to Enter the Nucleus*

A. Means, K. A. Anderson, T. Ribar, 2004, Journal of Biological Chemistry.