Niko Hensel

发表

Therapeutic Potential of Mesenchymal Stromal Cells and MSC Conditioned Medium in Amyotrophic Lateral Sclerosis (ALS) - In Vitro Evidence from Primary Motor Neuron Cultures, NSC-34 Cells, Astrocytes and Microglia

S. Petri, R. Dengler, P. Claus, 2013, PloS one.

The spinal muscular atrophy disease protein SMN is linked to the Rho-kinase pathway via profilin.

B. Wirth, A. Zeug, E. Ponimaskin, 2011, Human molecular genetics.

Intact interleukin-10 receptor signaling protects from hippocampal damage elicited by experimental neurotropic virus infection of SJL mice

M. Beckstette, W. Baumgärtner, P. Claus, 2018, Scientific Reports.

Neuronal Dysfunction in iPSC-Derived Medium Spiny Neurons from Chorea-Acanthocytosis Patients Is Reversed by Src Kinase Inhibition and F-Actin Stabilization

P. Claus, L. De Franceschi, A. Storch, 2016, The Journal of Neuroscience.

The phospho-landscape of the survival of motoneuron protein (SMN) protein: relevance for spinal muscular atrophy (SMA)

P. Claus, Niko Hensel, N. Detering, 2022, Cellular and Molecular Life Sciences.

Central and peripheral delivered AAV9-SMN are both efficient but target different pathomechanisms in a mouse model of spinal muscular atrophy

R. Kothary, Vincent Tabard-Cossa, B. Schneider, 2022, Gene Therapy.

Metalloprotease‐mediated cleavage of PlexinD1 and its sequestration to actin rods in the motoneuron disease spinal muscular atrophy (SMA)

B. Wirth, P. Claus, B. M. Verheijen, 2017, Human molecular genetics.

The spinal muscular atrophy disease protein SMN is linked to the rho-kinase pathway via proﬁlin

B. Wirth, A. Zeug, E. Ponimaskin, 2011 .

Microtubule associated protein 1B dysregulates microtubule dynamics and neuronal mitochondrial transport in Spinal Muscular Atrophy.

P. Claus, S. Rademacher, Niko Hensel, 2020, Human molecular genetics.

Suppression of the necroptotic cell death pathways improves survival in Smn2B/− mice

R. Kothary, Y. De Repentigny, M. Deguise, 2022, Frontiers in Cellular Neuroscience.

Renal pathology in a mouse model of severe Spinal Muscular Atrophy is associated with downregulation of Glial Cell-Line Derived Neurotrophic Factor (GDNF).

Daniel Kuhn, F. Quondamatteo, P. Claus, 2020, Human molecular genetics.

264th ENMC International Workshop: Multi-system involvement in spinal muscular atrophy Hoofddorp, the Netherlands, November 19th – 21st 2021

Ewout J. N. Groen, S. Corti, M. Bowerman, 2022, Neuromuscular Disorders.

Altered calcium dynamics and glutamate receptor properties in iPSC derived motor neurons from ALS patients with C9orf72, FUS, SOD1 or TDP43 mutations.

T. Cantz, T. Boeckers, S. Petri, 2019, Human molecular genetics.

The Proteome and Secretome of Cortical Brain Cells Infected With Herpes Simplex Virus

P. Claus, B. Sodeik, Benjamin Förthmann, 2020, Frontiers in Neurology.

HSV-1 triggers paracrine fibroblast growth factor response from cortical brain cells via immediate-early protein ICP0

P. Claus, S. Paludan, B. Sodeik, 2019, Journal of Neuroinflammation.

Chatting with the neighbors: crosstalk between Rho-kinase (ROCK) and other signaling pathways for treatment of neurological disorders

P. Claus, S. Rademacher, Niko Hensel, 2015, Front. Neurosci..

Bilateral crosstalk of rho- and extracellular-signal-regulated-kinase (ERK) pathways is confined to an unidirectional mode in spinal muscular atrophy (SMA).

P. Claus, C. Grothe, Hella Brinkmann, 2014, Cellular signalling.

Analysis of the Fibroblast Growth Factor System Reveals Alterations in a Mouse Model of Spinal Muscular Atrophy

P. Claus, C. Grothe, L. Klimaschewski, 2012, PloS one.

Impairment of the neurotrophic signaling hub B-Raf contributes to motoneuron degeneration in spinal muscular atrophy

S. Corti, P. Claus, A. Bergmann, 2021, Proceedings of the National Academy of Sciences.

Intact interleukin-10 receptor signaling protects from hippocampal damage elicited by experimental neurotropic virus infection of SJL mice

M. Beckstette, W. Baumgärtner, P. Claus, 2018, Scientific Reports.

Altered bone development with impaired cartilage formation precedes neuromuscular symptoms in Spinal Muscular Atrophy (SMA).

P. Claus, S. Lienenklaus, C. Neunaber, 2020, Human molecular genetics.

The Need for SMN-Independent Treatments of Spinal Muscular Atrophy (SMA) to Complement SMN-Enhancing Drugs

P. Claus, Niko Hensel, S. Kubinski, 2020, Frontiers in Neurology.

The Actin Cytoskeleton in SMA and ALS: How Does It Contribute to Motoneuron Degeneration?

P. Claus, Niko Hensel, 2018, The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry.

ERK and ROCK functionally interact in a signaling network that is compensationally upregulated in Spinal Muscular Atrophy

M. Gernert, P. Claus, Hella Brinkmann, 2017, Neurobiology of Disease.

Resolution of pathogenic R-loops rescues motor neuron degeneration in spinal muscular atrophy.

P. Claus, Niko Hensel, N. Detering, 2019, Brain : a journal of neurology.

Investigations of Microtubule-associated Protein 2 Gene Expression in Spinal Muscular Atrophy

P. Claus, Ceren Sucularlı, Niko Hensel, 2019, The Journal of Pediatric Research.

Fibroblast growth factor 23 signaling in hippocampal cells: impact on neuronal morphology and synaptic density

P. Claus, D. Haffner, Benjamin Förthmann, 2016, Journal of neurochemistry.

Central and peripheral delivery of AAV9-SMN target different pathomechanisms in a mouse model of spinal muscular atrophy

R. Kothary, Vincent Tabard-Cossa, B. Schneider, 2021 .

Profilin2a‐phosphorylation as a regulatory mechanism for actin dynamics

P. Claus, R. Lindner, G. Tsiavaliaris, 2019, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

HSV-1 triggers paracrine fibroblast growth factor response from cortical brain cells via immediate-early protein ICP0

P. Claus, S. Paludan, B. Sodeik, 2019, Journal of Neuroinflammation.