C. Holmes

Graeme Eisenhofer, V. Hearing, G. Eisenhofer, 2003, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Elevated cerebrospinal fluid ratios of cysteinyl-dopamine/3,4-dihydroxyphenylacetic acid in parkinsonian synucleinopathies.

D. Goldstein, Y. Sharabi, I. Kopin, 2016, Parkinsonism & related disorders.

3,4-Dihydroxyphenylethanol (Hydroxytyrosol) Mitigates the Increase in Spontaneous Oxidation of Dopamine During Monoamine Oxidase Inhibition in PC12 Cells

D. Goldstein, Y. Sharabi, I. Kopin, 2016, Neurochemical Research.

Comparison of Monoamine Oxidase Inhibitors in Decreasing Production of the Autotoxic Dopamine Metabolite 3,4-Dihydroxyphenylacetaldehyde in PC12 Cells

D. Goldstein, Y. Sharabi, I. Kopin, 2016, The Journal of Pharmacology and Experimental Therapeutics.

Substantial renal conversion of l-threo-3,4-dihydroxyphenylserine (droxidopa) to norepinephrine in patients with neurogenic orthostatic hypotension

D. Goldstein, G. Lamotte, C. Holmes, 2018, Clinical Autonomic Research.

Effects of Risperidone on the Peripheral Noradrenegic System in Patients with Schizophrenia: A Comparison with Clozapine and Placebo

A. Green, D. Goldstein, I. Elman, 2002, Neuropsychopharmacology.

The Effect of Clozapine on Plasma Norepinephrine: Relationship to Clinical Efficacy

R. Buchanan, D. Goldstein, A. Breier, 1994, Neuropsychopharmacology.

Plasma levels of catechols and metanephrines in neurogenic orthostatic hypotension

D. Goldstein, Y. Sharabi, G. Eisenhofer, 2003, Neurology.

Local sympathetic denervation in painful diabetic neuropathy.

D. Goldstein, C. Tack, Cees J Tack, 2002, Diabetes.

Local Sympathetic Denervation in Painful Diabetic

D. Goldstein, C. Holmes, P. Gurp, 2002 .

Determinants of buildup of the toxic dopamine metabolite DOPAL in Parkinson's disease

D. Mash, G. Miller, D. Goldstein, 2013, Journal of neurochemistry.

Progressive loss of cardiac sympathetic innervation in Parkinson's disease

D. Goldstein, C. Holmes, R. Dendi, 2002, Annals of neurology.

Neonatal diagnosis and treatment of Menkes disease.

D. Goldstein, N. Patronas, S. Kaler, 2008, The New England journal of medicine.

Coexpression of tyrosine hydroxylase, GTP cyclohydrolase I, aromatic amino acid decarboxylase, and vesicular monoamine transporter 2 from a helper virus-free herpes simplex virus type 1 vector supports high-level, long-term biochemical and behavioral correction of a rat model of Parkinson's disease.

Guo-Rong Zhang, Alfred I Geller, Lingxin Kong, 2004, Human gene therapy.

Failure of propranolol to prevent tilt-evoked systemic vasodilatation, adrenaline release and neurocardiogenic syncope.

D. Goldstein, J. Moak, B. Eldadah, 2006, Clinical science.

Occipital horn syndrome and a mild Menkes phenotype associated with splice site mutations at the MNK locus

D. Goldstein, W. Gahl, S. Kaler, 1994, Nature Genetics.

Supine low-frequency power of heart rate variability reflects baroreflex function, not cardiac sympathetic innervation

D. Goldstein, Y. Sharabi, J. Moak, 2009, Cleveland Clinic Journal of Medicine.

Supine low-frequency power of heart rate variability reflects baroreflex function, not cardiac sympathetic innervation.

D. Goldstein, Y. Sharabi, J. Moak, 2007, Heart rhythm.

Survival in synucleinopathies

D. Goldstein, Y. Sharabi, Tianxia Wu, 2015, Neurology.

Cardiac Sympathetic Denervation in Parkinson Disease

L. Metman, D. Goldstein, R. Cannon, 2000, Annals of Internal Medicine.

Partial cardiac sympathetic denervation after bilateral thoracic sympathectomy in humans.

D. Goldstein, J. Moak, B. Eldadah, 2005, Heart rhythm.

Sympathoadrenal function in patients with paroxysmal hypertension: pseudopheochromocytoma

D. Goldstein, O. Bentho, Y. Sharabi, 2007, Journal of hypertension.

Baroreflex Failure as a Late Sequela of Neck Irradiation

D. Goldstein, Y. Sharabi, C. Holmes, 2003, Hypertension.

Effects of alprazolam on pituitary-adrenal and catecholaminergic responses to metabolic stress in humans

R. Buchanan, D. Goldstein, D. Pickar, 1992, Biological Psychiatry.

Sympathoadrenal imbalance before neurocardiogenic syncope.

H. Calkins, D. Goldstein, S. Frank, 2003, The American journal of cardiology.

Orthostatic hypotension from sympathetic denervation in Parkinson’s disease

D. Goldstein, D S Goldstein, C S Holmes, 2002, Neurology.

Plasma catecholamines and blood volume in native Andeans during hypoxia and normoxia

F. Léon-Velarde, D. Goldstein, Y. Sharabi, 2006, Clinical Autonomic Research.

Sources and physiological significance of plasma dopamine sulfate.

D. Goldstein, S. Coppack, K. Swoboda, 1999, The Journal of clinical endocrinology and metabolism.

Genotype and phenotype in familial dysautonomia.

D. Goldstein, I. Kopin, F. Axelrod, 1998, Advances in pharmacology.

Cardiac implications of increased arterial entry and reversible 24-h central and peripheral norepinephrine levels in melancholia.

M. Wong, J. Licinio, D. Charney, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Cerebrospinal fluid biomarkers of central catecholamine deficiency in Parkinson's disease and other synucleinopathies.

D. Goldstein, Y. Sharabi, Courtney Holmes, 2012, Brain : a journal of neurology.

Patterns of cerebrospinal fluid catechols support increased central noradrenergic responsiveness in aging and Alzheimer’s disease

D. Goldstein, E. Peskind, M. Raskind, 1999, Biological Psychiatry.

Cardioselective peripheral noradrenergic deficiency in Lewy body synucleinopathies

D. Goldstein, G. Lamotte, A. Lenka, 2020, Annals of clinical and translational neurology.

Predominant Glandular Cholinergic Dysautonomia in Patients With Primary Sjögren's Syndrome

G. Illei, D. Goldstein, I. Alevizos, 2015, Arthritis & rheumatology.

Adrenomedullary Response to Glucagon in Patients with Primary Sjögren’s Syndrome

G. Illei, D. Goldstein, I. Alevizos, 2012, Cellular and Molecular Neurobiology.

Dopamine beta-hydroxylase deficiency associated with mutations in a copper transporter gene.

D. Goldstein, S. Kaler, C. Holmes, 1998, Advances in pharmacology.

Vesicular uptake blockade generates the toxic dopamine metabolite 3,4‐dihydroxyphenylacetaldehyde in PC12 cells: relevance to the pathogenesis of Parkinson's disease

D. Goldstein, Y. Sharabi, I. Kopin, 2012, Journal of neurochemistry.

Catechols in post‐mortem brain of patients with Parkinson disease

D. Goldstein, I. Kopin, C. Holmes, 2011, European journal of neurology.

Differential abnormalities of cerebrospinal fluid dopaminergic versus noradrenergic indices in synucleinopathies

D. Goldstein, Y. Sharabi, G. Lamotte, 2021, Journal of neurochemistry.

Do indices of baroreflex failure and peripheral noradrenergic deficiency predict the magnitude of orthostatic hypotension in Lewy body diseases?

D. Goldstein, Tianxia Wu, G. Lamotte, 2021, Clinical Autonomic Research.

Cardiac sympathetic denervation predicts PD in at-risk individuals.

D. Goldstein, Y. Sharabi, G. Lopez, 2017, Parkinsonism & related disorders.

Catecholaminergic effects of prolonged head-down bed rest.

J. Vernikos, V. Convertino, D. Goldstein, 1995, Journal of applied physiology.

Biomarkers to detect central dopamine deficiency and distinguish Parkinson disease from multiple system atrophy.

D. Goldstein, O. Bentho, Y. Sharabi, 2008, Parkinsonism & related disorders.

Neurotransmitter specificity of sympathetic denervation in Parkinson’s disease

D. Goldstein, Y. Sharabi, C. Holmes, 2003, Neurology.

Association Between Supine Hypertension and Orthostatic Hypotension in Autonomic Failure

D. Goldstein, Y. Sharabi, B. Eldadah, 2003, Hypertension.

Deficient vesicular storage: A common theme in catecholaminergic neurodegeneration.

A. Stefani, D. Mash, D. Goldstein, 2015, Parkinsonism & related disorders.

A vesicular sequestration to oxidative deamination shift in myocardial sympathetic nerves in Parkinson's disease

G. Miller, D. Goldstein, Y. Sharabi, 2014, Journal of neurochemistry.

Long-term trends in myocardial sympathetic innervation and function in synucleinopathies.

D. Goldstein, Tianxia Wu, G. Lamotte, 2019, Parkinsonism & related disorders.

Decreased vesicular storage and aldehyde dehydrogenase activity in multiple system atrophy.

D. Mash, D. Goldstein, Y. Sharabi, 2015, Parkinsonism & related disorders.

Cerebrospinal Fluid Biomarkers of Central Catecholamine Deficiency in Parkinson Disease and Other Synucleinopathies

D. Goldstein, Y. Sharabi, C. Holmes, 2014 .

Determinants of denervation-independent depletion of putamen dopamine in Parkinson's disease and multiple system atrophy.

D. Mash, D. Goldstein, Y. Sharabi, 2017, Parkinsonism & related disorders.

Contamination of the Norepinephrine Pro‐Drug Droxidopa by Dihydroxyphenylacetaldehyde

N. Whittaker, D. Goldstein, C. Holmes, 2010, Clinical chemistry.

Is 18F-DOPA a valid cardiac sympathetic neuroimaging agent?

D. Goldstein, C. Holmes, 2022, Clinical Autonomic Research.

Pure autonomic failure without synucleinopathy

D. Goldstein, Y. Sharabi, Risa Isonaka, 2017, Clinical Autonomic Research.

Association of anosmia with autonomic failure in Parkinson disease

D. Goldstein, L. Sewell, C. Holmes, 2010, Neurology.

Catecholamine metabolites affected by the copper-dependent enzyme dopamine-beta-hydroxylase provide sensitive biomarkers for early diagnosis of menkes disease and viral-mediated ATP7A gene therapy.

S. Kaler, C. Holmes, 2013, Advances in pharmacology.

Early copper therapy in classic Menkes disease patients with a novel splicing mutation

W. Gahl, S. Kaler, Richard C. Miller, 1995, Annals of neurology.

Association between cardiac denervation and parkinsonism caused by alpha-synuclein gene triplication.

A. Singleton, A. Singleton, A. Crawley, 2004, Brain : a journal of neurology.

Sympathetic Innervation in the MPTP Primate Model of Parkinson’s Disease

D. Goldstein, K. Bankiewicz, C. Holmes, 2003 .

Arteriovenous Differences in Plasma Concentrations of Catechols in Rats with Neuropathic Pain

S. Raja, C. Holmes, Y. Asano, 1995, Anesthesiology.

Correlates of urinary excretion of catechols in Humans

I. Armando, E. Grossman, H. Keiser, 1993 .

Clinical and therapeutic observations in aromatic l-amino acid decarboxylase deficiency

D. Goldstein, K. Swoboda, H. Levy, 1999, Neurology.

Predictive value of plasma catecholamine levels in neonatal detection of Menkes disease

S. Kaler, C. Holmes, Susan A. Berry, 1993, Journal of Inherited Metabolic Disease.

Cardiac 18F-Dopamine Positron Emission Tomography Predicts the Type of Phenoconversion of Pure Autonomic Failure

A. Lenka, C. Holmes, R. Isonaka, 2023, Research square.

Molecular, Clinical and Biochemical Characterization of a Mild Menkes Phenotype Associated with a Novel Missense Mutation (Ala1362Asp) in the ATP7A Copper Transport Gene. † 612

S. Kaler, C. Kaneski, C. Holmes, 1997, Pediatric Research.

Predominant Glandular Cholinergic Dysautonomia in Patients With Primary Sjögren's Syndrome

G. Illei, I. Alevizos, R. Imrich, 2015, Arthritis & rheumatology.

Effects of elevated plasma epinephrine on glucose utilization and blood flow in conscious rat brain.

L. Sokoloff, C. Kennedy, M. Cook, 1997, The American journal of physiology.

Survival in synucleinopathies

Y. Sharabi, Tianxia Wu, C. Holmes, 2015, Neurology.

Intra-neuronal vesicular uptake of catecholamines is decreased in patients with Lewy body diseases.

Y. Sharabi, I. Kopin, C. Holmes, 2011, The Journal of clinical investigation.

Baroreflex Failure as a Late Sequela of Neck Irradiation

Y. Sharabi, C. Holmes, R. Dendi, 2003, Hypertension.