A. Koskela

发表

Osteoblast-derived NOTUM reduces cortical bone mass in mice and the NOTUM locus is associated with bone mineral density in humans

F. Rivadeneira, S. Movérare-Skrtic, C. Ohlsson, 2019, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Inducible Wnt16 inactivation: WNT16 regulates cortical bone thickness in adult mice

K. Sjögren, M. Lagerquist, S. Movérare-Skrtic, 2018, The Journal of endocrinology.

SERMs have substance-specific effects on bone, and these effects are mediated via ERαAF-1 in female mice

P. Chambon, K. Sjögren, M. Lagerquist, 2016, American journal of physiology. Endocrinology and metabolism.

The bone-sparing effects of estrogen and WNT16 are independent of each other

J. Gustafsson, K. Sjögren, M. Lagerquist, 2015, Proceedings of the National Academy of Sciences.

Porcupine inhibitors impair trabecular and cortical bone mass and strength in mice

S. Movérare-Skrtic, C. Ohlsson, J. Tuukkanen, 2018, Journal of Endocrinology.

Synergistic effects of tributyltin and 2,3,7,8-tetrachlorodibenzo-p-dioxin on differentiating osteoblasts and osteoclasts.

J. Tuukkanen, M. Viluksela, A. Koskela, 2012, Toxicology and applied pharmacology.

Osteoblast-derived WNT16 represses osteoclastogenesis and prevents cortical bone fragility fractures

R. Baron, K. Sjögren, S. Movérare-Skrtic, 2014, Nature Medicine.

Estradiol and RSPO3 regulate vertebral trabecular bone mass independent of each other

S. Movérare-Skrtic, C. Ohlsson, J. Tuckermann, 2022, American journal of physiology. Endocrinology and metabolism.

The role of membrane ERα signaling in bone and other major estrogen responsive tissues

J. Gustafsson, M. Lagerquist, S. Movérare-Skrtic, 2016, Scientific Reports.

Increased bone mass in a mouse model with low fat mass.

K. Sjögren, M. Lagerquist, C. Ohlsson, 2018, American journal of physiology. Endocrinology and metabolism.

Bone as a target for persistent organic pollutants

A. Koskela, 2016 .

Prednisolone treatment reduces the osteogenic effects of loading in mice.

S. Windahl, C. Ohlsson, J. Tuukkanen, 2018, Bone.

Effects of developmental exposure to perfluorooctanoic acid (PFOA) on long bone morphology and bone cell differentiation.

J. Koponen, H. Håkansson, J. Tuukkanen, 2016, Toxicology and applied pharmacology.

Maternal beef and postweaning herring diets increase bone mineral density and strength in mouse offspring

I. Nookaew, C. Ohlsson, A. Holmäng, 2013, Experimental biology and medicine.

Osteocyte- and late Osteoblast-derived NOTUM Reduces Cortical Bone Mass in Mice.

S. Movérare-Skrtic, C. Ohlsson, J. Tuukkanen, 2021, American journal of physiology. Endocrinology and metabolism.

Androgen receptor SUMOylation regulates bone mass in male mice

S. Movérare-Skrtic, M. Poutanen, C. Ohlsson, 2019, Molecular and Cellular Endocrinology.

Membrane estrogen receptor α is essential for estrogen signaling in the male skeleton.

M. Lagerquist, S. Movérare-Skrtic, C. Ohlsson, 2018, The Journal of endocrinology.

Edinburgh Research Explorer SERMs have substance specific effects on bone and these effects are mediated via ERAF-1 in female mice

P. Chambon, K. Sjögren, M. Lagerquist, 2018 .

Perfluoroalkyl Substances and Abdominal Aortic Calcification

J. Schousboe, R. Nahhas, A. Ducatman, 2022, Journal of occupational and environmental medicine.

Osteoporosis in a murine model of postmenopausal lupus

M. Lagerquist, H. Carlsten, U. Islander, 2019, Lupus.

Transgene silencing of the Hutchinson‐Gilford progeria syndrome mutation results in a reversible bone phenotype, whereas resveratrol treatment does not show overall beneficial effects

C. Ohlsson, J. Tuukkanen, B. Rozell, 2015, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Perfluoroalkyl substances in human bone: concentrations in bones and effects on bone cell differentiation

P. Lehenkari, J. Koponen, J. Tuukkanen, 2017, Scientific Reports.

The role of activation functions 1 and 2 of estrogen receptor‐α for the effects of estradiol and selective estrogen receptor modulators in male mice

P. Chambon, K. Sjögren, M. Lagerquist, 2013 .

Liver-derived IGF-I regulates cortical bone mass but is dispensable for the osteogenic response to mechanical loading in female mice.

K. Sjögren, S. Windahl, C. Ohlsson, 2016, American journal of physiology. Endocrinology and metabolism.

Chapter 8. Bone as a Target for Endocrine Disruptors

N. Khalil, A. Koskela, 2020 .

RSPO3 is important for trabecular bone and fracture risk in mice and humans

T. Lehtimäki, J. Richards, S. Movérare-Skrtic, 2021, Nature Communications.

Endocrine, metabolic and apical effects of in utero and lactational exposure to non-dioxin-like 2,2´,3,4,4´,5,5´-heptachlorobiphenyl (PCB 180): A postnatal follow-up study in rats.

P. Heikkinen, J. Toppari, D. Schrenk, 2021, Reproductive toxicology.

Estrogen receptor-α in osteocytes is important for trabecular bone formation in male mice

K. Dahlman-Wright, J. Gustafsson, K. Sjögren, 2013, Proceedings of the National Academy of Sciences.

The Bone Sparing Effects of 2-Methoxyestradiol Are Mediated via Estrogen Receptor-α in Male Mice

C. Ohlsson, J. Tuukkanen, A. Eriksson, 2016, Endocrinology.

Enzalutamide Reduces the Bone Mass in the Axial But Not the Appendicular Skeleton in Male Mice.

K. Sjögren, M. Lagerquist, S. Movérare-Skrtic, 2016, Endocrinology.

The androgen receptor is required for maintenance of bone mass in adult male mice

K. Sjögren, S. Movérare-Skrtic, C. Ohlsson, 2019, Molecular and Cellular Endocrinology.

Expression of the Hutchinson-Gilford Progeria Mutation during Osteoblast Development Results in Loss of Osteocytes, Irregular Mineralization, and Poor Biomechanical Properties*

C. Ohlsson, J. Tuukkanen, O. Nilsson, 2012, The Journal of Biological Chemistry.

Acute fat loss does not affect bone mass

K. Sjögren, M. Lagerquist, C. Ohlsson, 2021, Scientific Reports.

Perfluoroalkyl substances, bone density, and cardio‐metabolic risk factors in obese 8–12 year old children: A pilot study

Ramzi W. Nahhas, T. Hangartner, K. Kannan, 2018, Environmental research.

B4GALNT3 regulates glycosylation of sclerostin and bone mass.

M. Lagerquist, S. Movérare-Skrtic, C. Ohlsson, 2023, EBioMedicine.

Female Mice Lacking Estrogen Receptor-α in Hypothalamic Proopiomelanocortin (POMC) Neurons Display Enhanced Estrogenic Response on Cortical Bone Mass

M. Lagerquist, S. Windahl, C. Ohlsson, 2016, Endocrinology.

The role of activation functions 1 and 2 of estrogen receptor‐α for the effects of estradiol and selective estrogen receptor modulators in male mice

P. Chambon, K. Sjögren, M. Lagerquist, 2013, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Estrogen receptor-α expression in neuronal cells affects bone mass

P. Chambon, M. Lagerquist, S. Windahl, 2012, Proceedings of the National Academy of Sciences.

Compressive loading of the murine tibia reveals site-specific micro-scale differences in adaptation and maturation rates of bone

A. E. Goodship, H. Isaksson, N. Mathavan, 2016, Osteoporosis International.

Clinically relevant doses of vitamin A decrease cortical bone mass in mice

S. Windahl, C. Ohlsson, H. Johansson, 2018, The Journal of endocrinology.

Estrogen receptor α (ERα) expression in neuronal cells affects bone mass

M. Lagerquist, S. Windahl, C. Ohlsson, 2012 .

The Bone Sparing Effects of 2-Methoxyestradiol Are Mediated via Estrogen Receptor- (cid:2) in Male Mice

J. Tuukkanen, Å. Tivesten, A. Eriksson, 2016 .

Osteoblast-derived WNT16 represses osteoclastogenesis and prevents cortical bone fragility fractures

R. Baron, K. Sjögren, S. Movérare-Skrtic, 2014, Nature Medicine.

Transplantation of gut microbiota from old mice into young healthy mice reduces lean mass but not bone mass

K. Sjögren, C. Ohlsson, K. Hveem, 2023, Gut microbes.