M. Jin

发表

Inducible Activation of FGFR2 in Adult Mice Promotes Bone Formation After Bone Marrow Ablation

Wei Xu, Xiaoling Xu, C. Deng, 2017, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Pulsed Electromagnetic Field Inhibits Synovitis via Enhancing the Efferocytosis of Macrophages

Peng Yang, Lin Chen, Xiaoqing Luo, 2020, BioMed research international.

A novel FGFR1-binding peptide exhibits anti-tumor effect on lung cancer by inhibiting proliferation and angiogenesis

Yuanqiang Wang, C. Deng, Zhifeng Huang, 2018, International journal of biological sciences.

Postnatal deletion of Alk5 gene in meniscal cartilage accelerates age‐dependent meniscal degeneration in mice

Di Chen, Wei Xu, C. Deng, 2018, Journal of cellular physiology.

Expansion of FGFR3-positive nucleus pulposus cells plays important roles in postnatal nucleus pulposus growth and regeneration

C. Deng, Lin Chen, Bo Chen, 2022, Stem cell research & therapy.

A novel FGFR1-binding peptide attenuates the degeneration of articular cartilage in adult mice.

C. Deng, X. Luo, X. Xu, 2018, Osteoarthritis and cartilage.

A novel fibroblast growth factor receptor 1 inhibitor protects against cartilage degradation in a murine model of osteoarthritis

Wei Xu, Chengguang Zhao, G. Liang, 2016, Scientific Reports.

TGF‐β/Alk5 signaling prevents osteoarthritis initiation via regulating the senescence of articular cartilage stem cells

Peng Yang, Lin Chen, Xiaoqing Luo, 2021, Journal of cellular physiology.

Gain-of-function mutation in FGFR3 in mice leads to decreased bone mass by affecting both osteoblastogenesis and osteoclastogenesis.

Di Chen, Yue Shen, H. Qi, 2010, Human molecular genetics.

Fgfr3 mutation disrupts chondrogenesis and bone ossification in zebrafish model mimicking CATSHL syndrome partially via enhanced Wnt/β-catenin signaling

Di Chen, Lin Chen, Xin Zhang, 2020, Theranostics.

A novel FGFR3-binding peptide inhibits FGFR3 signaling and reverses the lethal phenotype of mice mimicking human thanatophoric dysplasia.

C. Deng, Di Chen, P. Liu, 2012, Human molecular genetics.

Long term usage of dexamethasone accelerating the initiation of osteoarthritis via enhancing the extracellular matrix calcification and apoptosis of chondrocytes

Lin Chen, H. Qi, F. Luo, 2021, International journal of biological sciences.

FGFR3 deficiency enhances CXCL12-dependent chemotaxis of macrophages via upregulating CXCR7 and aggravates joint destruction in mice

Di Chen, L. Yin, C. Deng, 2019, Annals of the rheumatic diseases.

FGF/FGFR signaling in health and disease

Jian Q. Feng, Lin Chen, H. Qi, 2020, Signal Transduction and Targeted Therapy.

Spatially defined single-cell transcriptional profiling characterizes diverse chondrocyte subtypes and nucleus pulposus progenitors in human intervertebral discs

Y. Gan, P. Liu, Zhong Wang, 2021, Bone Research.

Cross‐talk between FGF and other cytokine signalling pathways during endochondral bone development

M. Jin, Xiaolan Du, Lin Chen, 2012, Cell biology international.

Imbalanced development of anterior and posterior thorax is a causative factor triggering scoliosis

P. Liu, Lin Chen, Haiyang Huang, 2019, Journal of orthopaedic translation.

Role of FGF/FGFR signaling in skeletal development and homeostasis: learning from mouse models

Nan Su, Min Jin, Lin Chen, 2014, Bone Research.

Intermittent PTH (1-34) injection rescues the retarded skeletal development and postnatal lethality of mice mimicking human achondroplasia and thanatophoric dysplasia.

C. Deng, Junbao Yang, C. Xian, 2012, Human molecular genetics.

Rmrp Mutation Disrupts Chondrogenesis and Bone Ossification in Zebrafish Model of Cartilage‐Hair Hypoplasia via Enhanced Wnt/β‐Catenin Signaling

Xiaoling Xu, L. Yin, C. Deng, 2019, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

FGFR3/fibroblast growth factor receptor 3 inhibits autophagy through decreasing the ATG12–ATG5 conjugate, leading to the delay of cartilage development in achondroplasia

Di Chen, Wei Xu, Xiaofen Wang, 2015, Autophagy.

A Pro253Arg mutation in fibroblast growth factor receptor 2 (Fgfr2) causes skeleton malformation mimicking human Apert syndrome by affecting both chondrogenesis and osteogenesis.

Xiaoling Xu, Cuiling Li, L. Yin, 2008, Bone.

FGFR3 induces degradation of BMP type I receptor to regulate skeletal development.

C. Deng, Y. Mishina, Di Chen, 2014, Biochimica et biophysica acta.

Continuous infusion of dexamethasone aggravates the damage of cartilage via upregulating p-AKT and impairing articular autophagy in experimental OA model

Lin Chen, H. Qi, F. Luo, 2020 .

New insights on the reparative cells in bone regeneration and repair

Lin Chen, M. Jin, N. Su, 2020, Biological reviews of the Cambridge Philosophical Society.

Targeting local lymphatics to ameliorate heterotopic ossification via FGFR3-BMPR1a pathway

Di Chen, L. Yin, Lin Chen, 2021, Nature Communications.