N. Su

发表

Inducible Activation of FGFR2 in Adult Mice Promotes Bone Formation After Bone Marrow Ablation

Wei Xu, Xiaoling Xu, C. Deng, 2017, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Pulsed Electromagnetic Field Inhibits Synovitis via Enhancing the Efferocytosis of Macrophages

Peng Yang, Lin Chen, Xiaoqing Luo, 2020, BioMed research international.

SQSTM1-dependent autophagic degradation of PKM2 inhibits the production of mature IL1B/IL-1β and contributes to LIPUS-mediated anti-inflammatory effect

Lin Chen, Q. Tan, N. Su, 2020, Autophagy.

Adeno-Associated Virus-Mediated RNAi against Mutant Alleles Attenuates Abnormal Calvarial Phenotypes in an Apert Syndrome Mouse Model

Xiaoling Xu, C. Deng, Zhugang Wang, 2018, Molecular therapy. Nucleic acids.

Gene expression patterns in bone following lipopolysaccharide stimulation

N. Su, Jing Yang, Lin Chen, 2014, Cellular & Molecular Biology Letters.

A novel FGFR1-binding peptide exhibits anti-tumor effect on lung cancer by inhibiting proliferation and angiogenesis

Yuanqiang Wang, C. Deng, Zhifeng Huang, 2018, International journal of biological sciences.

Exogenous fibroblast growth factor 9 attenuates cartilage degradation and aggravates osteophyte formation in post-traumatic osteoarthritis.

M. Xu, H. Chen, Y. Shen, 2016, Osteoarthritis and cartilage.

Deletion of FGFR3 in Osteoclast Lineage Cells Results in Increased Bone Mass in Mice by Inhibiting Osteoclastic Bone Resorption

Lin Chen, N. Su, Xiaolan Du, 2016, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Postnatal deletion of Alk5 gene in meniscal cartilage accelerates age‐dependent meniscal degeneration in mice

Di Chen, Wei Xu, C. Deng, 2018, Journal of cellular physiology.

Gain-of-function mutation of FGFR3 results in impaired fracture healing due to inhibition of chondrocyte differentiation.

Lin Chen, L. Yin, H. Qi, 2008, Biochemical and biophysical research communications.

Expansion of FGFR3-positive nucleus pulposus cells plays important roles in postnatal nucleus pulposus growth and regeneration

C. Deng, Lin Chen, Bo Chen, 2022, Stem cell research & therapy.

A novel FGFR1-binding peptide attenuates the degeneration of articular cartilage in adult mice.

C. Deng, X. Luo, X. Xu, 2018, Osteoarthritis and cartilage.

Bone function, dysfunction and its role in diseases including critical illness

Lin Chen, Hong Zhou, N. Su, 2019, International journal of biological sciences.

TGF‐β/Alk5 signaling prevents osteoarthritis initiation via regulating the senescence of articular cartilage stem cells

Peng Yang, Lin Chen, Xiaoqing Luo, 2021, Journal of cellular physiology.

Gain-of-function mutation in FGFR3 in mice leads to decreased bone mass by affecting both osteoblastogenesis and osteoclastogenesis.

Di Chen, Yue Shen, H. Qi, 2010, Human molecular genetics.

Fibroblast Growth Factor Receptor 3 Inhibits Osteoarthritis Progression in the Knee Joints of Adult Mice

W. Xu, Lin Chen, Quan Wang, 2016, Arthritis & rheumatology.

Conditional Deletion of Fgfr3 in Chondrocytes leads to Osteoarthritis-like Defects in Temporomandibular Joint of Adult Mice

Lin Chen, W. Xu, Yue Shen, 2016, Scientific Reports.

Fgfr3 mutation disrupts chondrogenesis and bone ossification in zebrafish model mimicking CATSHL syndrome partially via enhanced Wnt/β-catenin signaling

Di Chen, Lin Chen, Xin Zhang, 2020, Theranostics.

Deletion of Fgfr1 in Osteoblasts Enhances Mobilization of EPCs into Peripheral Blood in a Mouse Endotoxemia Model

Lin Chen, F. Luo, N. Su, 2014, International journal of biological sciences.

A novel FGFR3-binding peptide inhibits FGFR3 signaling and reverses the lethal phenotype of mice mimicking human thanatophoric dysplasia.

C. Deng, Di Chen, P. Liu, 2012, Human molecular genetics.

Generation of Fgfr3 Conditional Knockout Mice

Xiaoling Xu, Cuiling Li, C. Deng, 2010, International journal of biological sciences.

FGF signaling: its role in bone development and human skeleton diseases.

Lin Chen, N. Su, Xiao-xia Du, 2008, Frontiers in bioscience : a journal and virtual library.

Fibroblast growth factor receptor 1 regulates the differentiation and activation of osteoclasts through Erk1/2 pathway.

Yue Shen, Qifen He, Xiumin Lu, 2009, Biochemical and biophysical research communications.

Long term usage of dexamethasone accelerating the initiation of osteoarthritis via enhancing the extracellular matrix calcification and apoptosis of chondrocytes

Lin Chen, H. Qi, F. Luo, 2021, International journal of biological sciences.

Cartilage-specific deletion of Alk5 gene results in a progressive osteoarthritis-like phenotype in mice.

H. Chen, Q. Wang, D. Chen, 2017, Osteoarthritis and cartilage.

FGF/FGFR signaling in health and disease

Jian Q. Feng, Lin Chen, H. Qi, 2020, Signal Transduction and Targeted Therapy.

The exosome-like vesicles from osteoarthritic chondrocyte enhanced mature IL-1β production of macrophages and aggravated synovitis in osteoarthritis

L. Yin, Lin Chen, Xiaoqing Luo, 2019, Cell Death & Disease.

Overexpression of H1 calponin in osteoblast lineage cells leads to a decrease in bone mass by disrupting osteoblast function and promoting osteoclast formation

Di Chen, Qifen He, Ying Zhu, 2013, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Imbalanced development of anterior and posterior thorax is a causative factor triggering scoliosis

P. Liu, Lin Chen, Haiyang Huang, 2019, Journal of orthopaedic translation.

Role of FGF/FGFR signaling in skeletal development and homeostasis: learning from mouse models

Nan Su, Min Jin, Lin Chen, 2014, Bone Research.

Intermittent PTH (1-34) injection rescues the retarded skeletal development and postnatal lethality of mice mimicking human achondroplasia and thanatophoric dysplasia.

C. Deng, Junbao Yang, C. Xian, 2012, Human molecular genetics.

Rmrp Mutation Disrupts Chondrogenesis and Bone Ossification in Zebrafish Model of Cartilage‐Hair Hypoplasia via Enhanced Wnt/β‐Catenin Signaling

Xiaoling Xu, L. Yin, C. Deng, 2019, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

A Pro253Arg mutation in fibroblast growth factor receptor 2 (Fgfr2) causes skeleton malformation mimicking human Apert syndrome by affecting both chondrogenesis and osteogenesis.

Xiaoling Xu, Cuiling Li, L. Yin, 2008, Bone.

Continuous infusion of dexamethasone aggravates the damage of cartilage via upregulating p-AKT and impairing articular autophagy in experimental OA model

Lin Chen, H. Qi, F. Luo, 2020 .

Chondrocyte FGFR3 Regulates Bone Mass by Inhibiting Osteogenesis*

Lin Chen, Siru Zhou, N. Su, 2016, The Journal of Biological Chemistry.

New insights on the reparative cells in bone regeneration and repair

Lin Chen, M. Jin, N. Su, 2020, Biological reviews of the Cambridge Philosophical Society.

Astrocyte activation is suppressed in both normal and injured brain by FGF signaling

G. Fishell, J. Hébert, N. Su, 2014, Proceedings of the National Academy of Sciences.

Targeting local lymphatics to ameliorate heterotopic ossification via FGFR3-BMPR1a pathway

Di Chen, L. Yin, Lin Chen, 2021, Nature Communications.