Xiaolan Du

发表

Inducible Activation of FGFR2 in Adult Mice Promotes Bone Formation After Bone Marrow Ablation

Wei Xu, Xiaoling Xu, C. Deng, 2017, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Pulsed Electromagnetic Field Inhibits Synovitis via Enhancing the Efferocytosis of Macrophages

Peng Yang, Lin Chen, Xiaoqing Luo, 2020, BioMed research international.

Anemonin attenuates osteoarthritis progression through inhibiting the activation of IL‐1β/NF‐κB pathway

Wei Xu, Lin Chen, F. Luo, 2017, Journal of cellular and molecular medicine.

Low‐intensity pulsed ultrasound inhibits VEGFA expression in chondrocytes and protects against cartilage degeneration in experimental osteoarthritis

Dingqun Bai, Ying Zhu, H. Qi, 2020, FEBS open bio.

SQSTM1-dependent autophagic degradation of PKM2 inhibits the production of mature IL1B/IL-1β and contributes to LIPUS-mediated anti-inflammatory effect

Lin Chen, Q. Tan, N. Su, 2020, Autophagy.

Adeno-Associated Virus-Mediated RNAi against Mutant Alleles Attenuates Abnormal Calvarial Phenotypes in an Apert Syndrome Mouse Model

Xiaoling Xu, C. Deng, Zhugang Wang, 2018, Molecular therapy. Nucleic acids.

P53-Rb signaling pathway is involved in tubular cell senescence in renal ischemia/reperfusion injury.

Zhao Lin, Kai-long Li, Xiaolan Du, 2007, Biocell : official journal of the Sociedades Latinoamericanas de Microscopia Electronica ... et. al.

Loss of Fgfr1 in chondrocytes inhibits osteoarthritis by promoting autophagic activity in temporomandibular joint

Lin Chen, F. Luo, Q. Tan, 2018, The Journal of Biological Chemistry.

A novel FGFR1-binding peptide exhibits anti-tumor effect on lung cancer by inhibiting proliferation and angiogenesis

Yuanqiang Wang, C. Deng, Zhifeng Huang, 2018, International journal of biological sciences.

Deletion of FGFR3 in Osteoclast Lineage Cells Results in Increased Bone Mass in Mice by Inhibiting Osteoclastic Bone Resorption

Lin Chen, N. Su, Xiaolan Du, 2016, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Postnatal deletion of Alk5 gene in meniscal cartilage accelerates age‐dependent meniscal degeneration in mice

Di Chen, Wei Xu, C. Deng, 2018, Journal of cellular physiology.

Gain-of-function mutation of FGFR3 results in impaired fracture healing due to inhibition of chondrocyte differentiation.

Lin Chen, L. Yin, H. Qi, 2008, Biochemical and biophysical research communications.

Is there a relationship between bone and critical illness?

Xiaolan Du, Lin Chen, Yao-zong Zhang, 2011, Medical hypotheses.

Expansion of FGFR3-positive nucleus pulposus cells plays important roles in postnatal nucleus pulposus growth and regeneration

C. Deng, Lin Chen, Bo Chen, 2022, Stem cell research & therapy.

A novel fibroblast growth factor receptor 1 inhibitor protects against cartilage degradation in a murine model of osteoarthritis

Wei Xu, Chengguang Zhao, G. Liang, 2016, Scientific Reports.

Deformed Skull Morphology Is Caused by the Combined Effects of the Maldevelopment of Calvarias, Cranial Base and Brain in FGFR2-P253R Mice Mimicking Human Apert Syndrome

Wei Xu, Xiaoqing Luo, F. Luo, 2017, International journal of biological sciences.

The exosome-like vesicles from osteoarthritic chondrocyte enhanced mature IL-1β production of macrophages and aggravated synovitis in osteoarthritis

L. Yin, Lin Chen, Xiaoqing Luo, 2019, Cell Death & Disease.

Bone function, dysfunction and its role in diseases including critical illness

Lin Chen, Hong Zhou, N. Su, 2019, International journal of biological sciences.

TGF‐β/Alk5 signaling prevents osteoarthritis initiation via regulating the senescence of articular cartilage stem cells

Peng Yang, Lin Chen, Xiaoqing Luo, 2021, Journal of cellular physiology.

Gain-of-function mutation in FGFR3 in mice leads to decreased bone mass by affecting both osteoblastogenesis and osteoclastogenesis.

Di Chen, Yue Shen, H. Qi, 2010, Human molecular genetics.

Fibroblast Growth Factor Receptor 3 Inhibits Osteoarthritis Progression in the Knee Joints of Adult Mice

W. Xu, Lin Chen, Quan Wang, 2016, Arthritis & rheumatology.

Running title : FGFR 3 protects the articular cartilage from degeneration

Lin Chen, Quan Wang, Junlan Huang, 2016 .

Fgfr3 mutation disrupts chondrogenesis and bone ossification in zebrafish model mimicking CATSHL syndrome partially via enhanced Wnt/β-catenin signaling

Di Chen, Lin Chen, Xin Zhang, 2020, Theranostics.

Deletion of Fgfr1 in Osteoblasts Enhances Mobilization of EPCs into Peripheral Blood in a Mouse Endotoxemia Model

Lin Chen, F. Luo, N. Su, 2014, International journal of biological sciences.

A novel FGFR3-binding peptide inhibits FGFR3 signaling and reverses the lethal phenotype of mice mimicking human thanatophoric dysplasia.

C. Deng, Di Chen, P. Liu, 2012, Human molecular genetics.

Generation of Fgfr3 Conditional Knockout Mice

Xiaoling Xu, Cuiling Li, C. Deng, 2010, International journal of biological sciences.

Fibroblast Growth Factor Receptor 3 Deficiency Does Not Impair the Osteoanabolic Action of Parathyroid Hormone on Mice

C. Xian, F. Luo, Junlan Huang, 2016, International journal of biological sciences.

Fibroblast growth factor receptor 1 regulates the differentiation and activation of osteoclasts through Erk1/2 pathway.

Yue Shen, Qifen He, Xiumin Lu, 2009, Biochemical and biophysical research communications.

FGFR3 deficient mice have accelerated fracture repair

Wei Xu, F. Luo, Q. Tan, 2017, International journal of biological sciences.

Long term usage of dexamethasone accelerating the initiation of osteoarthritis via enhancing the extracellular matrix calcification and apoptosis of chondrocytes

Lin Chen, H. Qi, F. Luo, 2021, International journal of biological sciences.

FGFR3 deficiency enhances CXCL12-dependent chemotaxis of macrophages via upregulating CXCR7 and aggravates joint destruction in mice

Di Chen, L. Yin, C. Deng, 2019, Annals of the rheumatic diseases.

Loss of Fgfr1 in chondrocytes inhibits osteoarthritis through promoting autophagic activity in temporomandibular joint

Lin Chen, F. Luo, Q. Tan, 2017 .

Dstyk mutation leads to congenital scoliosis-like vertebral malformations in zebrafish via dysregulated mTORC1/TFEB pathway

L. Yin, C. Deng, P. Liu, 2020, Nature Communications.

Cross‐talk between FGF and other cytokine signalling pathways during endochondral bone development

M. Jin, Xiaolan Du, Lin Chen, 2012, Cell biology international.

Overexpression of H1 calponin in osteoblast lineage cells leads to a decrease in bone mass by disrupting osteoblast function and promoting osteoclast formation

Di Chen, Qifen He, Ying Zhu, 2013, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Imbalanced development of anterior and posterior thorax is a causative factor triggering scoliosis

P. Liu, Lin Chen, Haiyang Huang, 2019, Journal of orthopaedic translation.

Recent research on the growth plate: Advances in fibroblast growth factor signaling in growth plate development and disorders.

Lin Chen, Siru Zhou, Hangang Chen, 2014, Journal of molecular endocrinology.

Intermittent PTH (1-34) injection rescues the retarded skeletal development and postnatal lethality of mice mimicking human achondroplasia and thanatophoric dysplasia.

C. Deng, Junbao Yang, C. Xian, 2012, Human molecular genetics.

Genetic inhibition of fibroblast growth factor receptor 1 in knee cartilage attenuates the degeneration of articular cartilage in adult mice.

Di Chen, Qian Chen, C. Deng, 2012, Arthritis and rheumatism.

Role of FGFs/FGFRs in skeletal development and bone regeneration

C. Xian, Yangli Xie, Xiaolan Du, 2012, Journal of cellular physiology.

Rmrp Mutation Disrupts Chondrogenesis and Bone Ossification in Zebrafish Model of Cartilage‐Hair Hypoplasia via Enhanced Wnt/β‐Catenin Signaling

Xiaoling Xu, L. Yin, C. Deng, 2019, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Exosomes: roles and therapeutic potential in osteoarthritis

Lin Chen, Xiaoqing Luo, Siru Zhou, 2020, Bone Research.

FGFR3/fibroblast growth factor receptor 3 inhibits autophagy through decreasing the ATG12–ATG5 conjugate, leading to the delay of cartilage development in achondroplasia

Di Chen, Wei Xu, Xiaofen Wang, 2015, Autophagy.

A Pro253Arg mutation in fibroblast growth factor receptor 2 (Fgfr2) causes skeleton malformation mimicking human Apert syndrome by affecting both chondrogenesis and osteogenesis.

Xiaoling Xu, Cuiling Li, L. Yin, 2008, Bone.

FGFR3 induces degradation of BMP type I receptor to regulate skeletal development.

C. Deng, Y. Mishina, Di Chen, 2014, Biochimica et biophysica acta.

Continuous infusion of dexamethasone aggravates the damage of cartilage via upregulating p-AKT and impairing articular autophagy in experimental OA model

Lin Chen, H. Qi, F. Luo, 2020 .

Chondrocyte FGFR3 Regulates Bone Mass by Inhibiting Osteogenesis*

Lin Chen, Siru Zhou, N. Su, 2016, The Journal of Biological Chemistry.