T. Asaki

发表

Interaction of oxygen with TiN(001): N<-->O exchange and oxidation process.

K. Nakamura, J. Rodríguez, J. Graciani, 2007, The Journal of chemical physics.

Structure-activity studies on diphenylpyrazine derivatives: a novel class of prostacyclin receptor agonists.

Y. Sugiyama, T. Asaki, K. Kuwabara, 2007, Bioorganic & medicinal chemistry.

Selexipag: An Oral and Selective IP Prostacyclin Receptor Agonist for the Treatment of Pulmonary Arterial Hypertension.

M. Clozel, J. Gatfield, T. Asaki, 2015, Journal of medicinal chemistry.

Structure–activity studies on 1,3-dioxane-2-carboxylic acid derivatives, a novel class of subtype-selective peroxisome proliferator-activated receptor α (PPARα) agonists

Y. Sugiyama, T. Asaki, K. Kuwabara, 2008 .

Discovery of a novel class of 1,3-dioxane-2-carboxylic acid derivatives as subtype-selective peroxisome proliferator-activated receptor alpha (PPARalpha) agonists.

Y. Sugiyama, T. Asaki, K. Kuwabara, 2008, Bioorganic & medicinal chemistry letters.

Long-Acting Prostacyclin Receptor Agonist Prodrug

A. Hashino, T. Asaki, K. Kuwabara, 2007 .

Synthesis and evaluation of N-acylsulfonamide and N-acylsulfonylurea prodrugs of a prostacyclin receptor agonist.

T. Asaki, A. Nakamura, T. Yamada, 2007, Bioorganic & medicinal chemistry.

2- -N-(methylsulfonyl)acetamide (NS-304), an Orally Available and Long-Acting Prostacyclin Receptor Agonist Prodrug

K. Kuwano, A. Hashino, K. Okubo, 2007 .

Design and synthesis of 3-substituted benzamide derivatives as Bcr-Abl kinase inhibitors.

T. Niwa, Y. Sugiyama, T. Asaki, 2006, Bioorganic & medicinal chemistry letters.

NS-187 (INNO-406), a Bcr-Abl/Lyn Dual Tyrosine Kinase Inhibitor

T. Niwa, S. Kimura, T. Asaki, 2007, Analytical chemistry insights.

NS-187, a potent and selective dual Bcr-Abl/Lyn tyrosine kinase inhibitor, is a novel agent for imatinib-resistant leukemia.

Tomoko Niwa, Takeshi Yuasa, Eri Kawata, 2005, Blood.

Structural factors contributing to the Abl/Lyn dual inhibitory activity of 3-substituted benzamide derivatives.

T. Niwa, T. Asaki, T. Horio, 2007, Bioorganic & medicinal chemistry letters.

A Novel Selective Peroxisome Proliferator-Activated Receptor α Agonist, 2-Methyl-c-5-[4-[5-methyl-2-(4-methylphenyl)-4-oxazolyl]butyl]-1,3-dioxane-r-2-carboxylic acid (NS-220), Potently Decreases Plasma Triglyceride and Glucose Levels and Modifies Lipoprotein Profiles in KK-Ay Mice

J. Yano, M. Murai, T. Asaki, 2004, Journal of Pharmacology and Experimental Therapeutics.

2-{4-[(5,6-Diphenylpyrazin-2-yl)(isopropyl)amino]butoxy}-N-(methylsulfonyl)acetamide (NS-304), an Orally Available and Long-Acting Prostacyclin Receptor Agonist Prodrug

Tetsuhiro Yamada, Asami Hashino, Kenji Kuwabara, 2007, Journal of Pharmacology and Experimental Therapeutics.