Ute Galm

发表

Expression of biosynthetic gene clusters in heterologous hosts for natural product production and combinatorial biosynthesis

B. Shen, Ute Galm, 2006, Expert opinion on drug discovery.

Heterologous Expression of Novobiocin and Clorobiocin Biosynthetic Gene Clusters

K. Chater, L. Heide, B. Gust, 2005, Applied and Environmental Microbiology.

In vitro and in vivo production of new aminocoumarins by a combined biochemical, genetic, and synthetic approach.

L. Wessjohann, L. Heide, Jürgen Schmidt, 2004, Chemistry & biology.

Functional characterization of tlmH in Streptoalloteichus hindustanus E465-94 ATCC 31158 unveiling new insight into tallysomycin biosynthesis and affording a novel bleomycin analog.

B. Shen, Zhinan Xu, M. Tao, 2010, Molecular bioSystems.

The tallysomycin biosynthetic gene cluster from Streptoalloteichus hindustanus E465-94 ATCC 31158 unveiling new insights into the biosynthesis of the bleomycin family of antitumor antibiotics.

B. Shen, N. George, M. Tao, 2007, Molecular bioSystems.

Functional Characterization of tlmK Unveiling Unstable Carbinolamide Intermediates in the Tallysomycin Biosynthetic Pathway*

B. Shen, M. Tao, Ute Galm, 2009, Journal of Biological Chemistry.

Antimicrobial and DNA Gyrase-Inhibitory Activities of Novel Clorobiocin Derivatives Produced by Mutasynthesis

M. Page, L. Heide, Shu‐Ming Li, 2004, Antimicrobial Agents and Chemotherapy.

Natural product drug discovery: the times have never been better.

Ben Shen, B. Shen, Ute Galm, 2007, Chemistry & biology.

Natural product derived insecticides: discovery and development of spinetoram

T. Sparks, Ute Galm, T. C. Sparks, 2016, Journal of Industrial Microbiology & Biotechnology.

A designer bleomycin with significantly improved DNA cleavage activity.

B. Shen, M. Tao, Y. Duan, 2012, Journal of the American Chemical Society.

In Vivo Manipulation of the Bleomycin Biosynthetic Gene Cluster in Streptomyces verticillus ATCC15003 Revealing New Insights into Its Biosynthetic Pathway*

B. Shen, Wen Liu, M. Tao, 2008, Journal of Biological Chemistry.

Comparative analysis of the biosynthetic gene clusters and pathways for three structurally related antitumor antibiotics: bleomycin, tallysomycin, and zorbamycin.

B. Shen, M. Tao, E. Wendt-Pienkowski, 2011, Journal of natural products.

The biosynthetic gene cluster of zorbamycin, a member of the bleomycin family of antitumor antibiotics, from Streptomyces flavoviridis ATCC 21892.

B. Shen, N. George, M. Tao, 2009, Molecular bioSystems.

Glycopeptide antitumor antibiotic zorbamycin from Streptomyces flavoviridis ATCC 21892: strain improvement and structure elucidation.

B. Shen, N. George, M. Tao, 2007, Journal of natural products.

Antitumor antibiotics: bleomycin, enediynes, and mitomycin.

B. Shen, M. Hager, J. Thorson, 2005, Chemical reviews.

New aminocoumarin antibiotics from a cloQ-defective mutant of the clorobiocin producer Streptomyces roseochromogenes DS12.976.

L. Heide, Shu‐Ming Li, A. Freitag, 2004, The Journal of antibiotics.

Cloning and analysis of the simocyclinone biosynthetic gene cluster of Streptomyces antibioticus Tü 6040

L. Heide, H. Fiedler, Jürgen Schmidt, 2002, Archives of Microbiology.

BlmB and TlmB Provide Resistance to the Bleomycin Family of Antitumor Antibiotics by N-Acetylating Metal-Free Bleomycin, Tallysomycin, Phleomycin, and Zorbamycin

B. Shen, M. Tao, J. Rudolf, 2014, Biochemistry.

In Vivo Manipulation of the Bleomycin Biosynthetic Gene Cluster in Streptomyces verticillus ATCC15003 Revealing New Insights into Its Biosynthetic Pathway*

B. Shen, Wen Liu, M. Tao, 2008, Journal of Biological Chemistry.