Roland Stragies

发表

Suppression and Regression of Choroidal Neovascularization by Systemic Administration of an α5β1 Integrin Antagonist

P. Campochiaro, S. Kachi, G. Zahn, 2006, Molecular Pharmacology.

Suppression and regression of choroidal neovascularization by systemic administration of an alpha5beta1 integrin antagonist.

P. Campochiaro, S. Kachi, G. Zahn, 2006, Molecular pharmacology.

The role of integrin α5β1 in the regulation of corneal neovascularization

A. Joussen, G. Zahn, N. Kociok, 2007 .

Inhibition of Inflammatory Lymphangiogenesis by Integrin α5 Blockade

F. Kruse, C. Cursiefen, G. Zahn, 2007 .

An α5β1 integrin inhibitor attenuates glioma growth

H. Kettenmann, N. Rooijen, M. Synowitz, 2008, Molecular and Cellular Neuroscience.

Assessment of the integrin alpha5beta1 antagonist JSM6427 in proliferative vitreoretinopathy using in vitro assays and a rabbit model of retinal detachment.

E. A. Chapin, F. Holz, A. Adamis, 2010, Investigative ophthalmology & visual science.

Design and Synthesis of a New Class of Selective Integrin α5β1 Antagonists

U. Reimer, G. Zahn, D. Vossmeyer, 2007 .

Discovery of orally available integrin alpha5beta1 antagonists.

G. Zahn, D. Vossmeyer, Roland Stragies, 2010, Bioorganic & medicinal chemistry letters.

SAR of N-phenyl piperidine based oral integrin alpha5beta1 antagonists.

G. Zahn, D. Vossmeyer, Roland Stragies, 2010, Bioorganic & medicinal chemistry letters.

Preclinical evaluation of the novel small-molecule integrin alpha5beta1 inhibitor JSM6427 in monkey and rabbit models of choroidal neovascularization.

A. Adamis, G. Zahn, M. Wills, 2009, Archives of ophthalmology.

A Crossed Yne–Ene Metathesis Showing Atom Economy†

S. Blechert, Roland Stragies, M. Schuster, 1997 .

A novel ruthenium-catalysed tandem diyne cycloisomerisation—cross metathesis process

S. Blechert, Roland Stragies, M. Schuster, 1999 .

Preparation and properties of chiral 4-pyrrolidinopyridine (PPY) analogues with dual functional side chains

T. Kawabata, K. Fuji, Y. Nagaoka, 2003 .

Total synthesis of (−)-halosaline by a ruthenium-catalyzed ring rearrangement

S. Blechert, Roland Stragies, S. Blechert*, 1999 .

Improved yne–ene-cross metathesis utilizing a dihydroimidazole carbene ruthenium complex

S. Blechert, Roland Stragies, U. Voigtmann, 2000 .

Asymmetric synthesis of indolizidine alkaloids by ring-closing–ring-opening metathesis

H. Ovaa, J. H. Boom, S. Blechert, 2000 .

Inhibition of inflammatory lymphangiogenesis by integrin alpha5 blockade.

F. Kruse, C. Cursiefen, G. Zahn, 2007, The American journal of pathology.

Regioselective Acylation of Octyl β-d-Glucopyranoside by Chiral 4-Pyrrolidinopyridine Analogues

T. Kawabata, Roland Stragies, T. Shibata, 2008 .

Preclinical Evaluation of the Novel Small-Molecule Integrin (cid:2) 5 (cid:3) 1 Inhibitor JSM6427 in Monkey and Rabbit Models of Choroidal Neovascularization

A. Adamis, G. Zahn, M. Wills, 2009 .

Modulation of Hypoxia-Induced Neovascularization by JSM6427, an Integrin α5β 1 Inhibiting Molecule

A. Joussen, Anna-Karina B. Maier, G. Zahn, 2006 .

Novel small molecule bradykinin B1 receptor antagonists. Part 3: hydroxyurea derivatives.

K. Schnatbaum, C. Gibson, M. Schaudt, 2010, Bioorganic & medicinal chemistry letters.

Novel small molecule bradykinin B1 receptor antagonists. Part 1: benzamides and semicarbazides.

K. Schnatbaum, C. Gibson, M. Schaudt, 2010, Bioorganic & medicinal chemistry letters.

Novel small molecule bradykinin B1 receptor antagonists. Part 2: 5-membered diaminoheterocycles.

K. Schnatbaum, C. Gibson, M. Schaudt, 2010, Bioorganic & medicinal chemistry letters.

Conformational control of integrin-subtype selectivity in isoDGR peptide motifs: a biological switch.

E. Novellino, H. Schiller, H. Kessler, 2010, Angewandte Chemie.

Rational Design of Highly Active and Selective Ligands for the α5β1 Integrin Receptor

H. Kessler, G. Zahn, D. Heckmann, 2008, Chembiochem : a European journal of chemical biology.

Breaking the dogma of the metal-coordinating carboxylate group in integrin ligands: introducing hydroxamic acids to the MIDAS to tune potency and selectivity.

E. Novellino, H. Kessler, V. Limongelli, 2009, Angewandte Chemie.

Probing Integrin Selectivity: Rational Design of Highly Active and Selective Ligands for the α5β1 and αvβ3 Integrin Receptor

H. Kessler, L. Marinelli, G. Zahn, 2007 .

Probing integrin selectivity: rational design of highly active and selective ligands for the alpha5beta1 and alphavbeta3 integrin receptor.

H. Kessler, L. Marinelli, G. Zahn, 2007, Angewandte Chemie.

The role of integrin alpha5beta1 in the regulation of corneal neovascularization.

A. Joussen, G. Zahn, N. Kociok, 2007, Experimental eye research.

Modulation of hypoxia-induced neovascularization by JSM6427, an integrin alpha5beta1 inhibiting molecule.

A. Joussen, Anna-Karina B. Maier, G. Zahn, 2007, Current eye research.

Design and synthesis of a new class of selective integrin alpha5beta1 antagonists.

U. Reimer, G. Zahn, D. Vossmeyer, 2007, Journal of medicinal chemistry.

A Novel Ruthenium-Catalyzed Tandem Diyne Cycloisomerization—Cross Metathesis Process.

Roland Stragies, M. Schuster, S. Blechert*, 2010 .

Remote chirality transfer in nucleophilic catalysis with N-(4-pyridinyl)-L-proline derivatives.

T. Kawabata, Roland Stragies, Takayuki Fukaya, 2003, Chirality.