N. Takahashi

发表

Class II HDACs mediate CaMK-dependent signaling to NRSF in ventricular myocytes.

K. Nakao, K. Tanimoto, Yoshihiko Saito, 2006, Journal of molecular and cellular cardiology.

Cardiotrophin-1 phosphorylates akt and BAD, and prolongs cell survival via a PI3K-dependent pathway in cardiac myocytes.

I. Kishimoto, Y. Miyamoto, I Kishimoto, 2000, Journal of molecular and cellular cardiology.

Hypertrophic responses to cardiotrophin-1 are not mediated by STAT3, but via a MEK5-ERK5 pathway in cultured cardiomyocytes.

K. Nakao, A. Yoshimura, K. Tanimoto, 2005, Journal of molecular and cellular cardiology.

SOCS1/JAB likely mediates the protective effect of cardiotrophin-1 against lipopolysaccharide-induced left ventricular dysfunction in vivo.

K. Nakao, A. Yoshimura, K. Tanimoto, 2005, Circulation journal : official journal of the Japanese Circulation Society.

Endothelin-1 and cardiotrophin-1 induce brain natriuretic peptide gene expression by distinct transcriptional mechanisms.

N. Tamura, I. Masuda, O. Nakagawa, 1998, Journal of cardiovascular pharmacology.

Involvement of cardiotrophin-1 in cardiac myocyte-nonmyocyte interactions during hypertrophy of rat cardiac myocytes in vitro.

I. Masuda, O. Nakagawa, Y. Miyamoto, 1999, Circulation.

Interaction of myocytes and nonmyocytes is necessary for mechanical stretch to induce ANP/BNP production in cardiocyte culture.

H. Itoh, I. Masuda, O. Nakagawa, 1998, Journal of cardiovascular pharmacology.

Effects of cardiotrophin-1 on hemodynamics and endocrine function of the heart.

I. Masuda, I. Kishimoto, T. Nishikimi, 2000, American journal of physiology. Heart and circulatory physiology.

NRSF regulates the fetal cardiac gene program and maintains normal cardiac structure and function

K. Nakao, A. Noma, M. Horie, 2003, The EMBO journal.

Androgen contributes to gender-related cardiac hypertrophy and fibrosis in mice lacking the gene encoding guanylyl cyclase-A.

K. Nakao, A. Fukamizu, K. Tanimoto, 2004, Endocrinology.

Guanylyl Cyclase-A Inhibits Angiotensin II Type 1A Receptor-Mediated Cardiac Remodeling, an Endogenous Protective Mechanism in the Heart

K. Nakao, A. Fukamizu, K. Tanimoto, 2002, Circulation.

Overexpression of Brain Natriuretic Peptide Facilitates Neutrophil Infiltration and Cardiac Matrix Metalloproteinase-9 Expression After Acute Myocardial Infarction

K. Nakao, N. Tamura, K. Tanimoto, 2004, Circulation.

Fibronectin signaling stimulates BNP gene transcription by inhibiting neuron-restrictive silencer element-dependent repression.

K. Nakao, Y. Naruse, I. Kishimoto, 2002, Cardiovascular research.

Angiotensin II-induced ventricular hypertrophy and extracellular signal-regulated kinase activation are suppressed in mice overexpressing brain natriuretic peptide in circulation.

K. Nakao, I. Kishimoto, Yoshihiko Saito, 2003, Hypertension research : official journal of the Japanese Society of Hypertension.

Angiotensin II Type 2 Receptor Deficiency Exacerbates Heart Failure and Reduces Survival After Acute Myocardial Infarction in Mice

K. Nakao, K. Tanimoto, M. Iwai, 2003, Circulation.

A heart-specific increase in cardiotrophin-1 gene expression precedes the establishment of ventricular hypertrophy in genetically hypertensive rats.

I. Masuda, O. Nakagawa, T. Hosoya, 1999, Journal of hypertension.

The effects of the selective ROCK inhibitor, Y27632, on ET‐1‐induced hypertrophic response in neonatal rat cardiac myocytes – possible involvement of Rho/ROCK pathway in cardiac muscle cell hypertrophy

K. Nakao, N. Tamura, O. Nakagawa, 1999, FEBS letters.

The Neuron-Restrictive Silencer Element–Neuron-Restrictive Silencer Factor System Regulates Basal and Endothelin 1-Inducible Atrial Natriuretic Peptide Gene Expression in Ventricular Myocytes

K. Nakao, Y. Naruse, I. Kishimoto, 2001, Molecular and Cellular Biology.

Continuous administration of nicorandil decreases QT dispersion during the chronic phase of acute myocardial infarction.

Y. Hiraoka, N. Takahashi, I. Hamanaka, 2006, International heart journal.

The heart is a source of circulating cardiotrophin-1 in humans.

I. Kishimoto, H. Yasue, M. Harada, 2000, Biochemical and biophysical research communications.

Replication protein A1 reduces transcription of the endothelial nitric oxide synthase gene containing a -786T-->C mutation associated with coronary spastic angina.

K. Kangawa, I. Kishimoto, H. Yasue, 2000, Human molecular genetics.

Yukio Hypertension Endothelial Nitric Oxide Synthase Gene Is Positively Associated With Essential

K. Nakao, H. Itoh, I. Masuda, 1998 .

Endothelial nitric oxide synthase gene is positively associated with essential hypertension.

H. Itoh, I. Masuda, T. Akamizu, 1998, Hypertension.

Blockade of the natriuretic peptide receptor guanylyl cyclase-A inhibits NF-kappaB activation and alleviates myocardial ischemia/reperfusion injury.

D. Garbers, G. Takemura, I. Kishimoto, 2001, The Journal of clinical investigation.

Induction of JAB/SOCS-1/SSI-1 and CIS3/SOCS-3/SSI-3 Is Involved in gp130 Resistance in Cardiovascular System in Rat Treated With Cardiotrophin-1 In Vivo

K. Nakao, A. Yoshimura, I. Masuda, 2001, Circulation research.

Outside-in signalling of fibronectin stimulates cardiomyocyte hypertrophy in cultured neonatal rat ventricular myocytes.

I. Masuda, O. Nakagawa, I. Kishimoto, 2000, Journal of molecular and cellular cardiology.

Role of Natriuretic Peptide Receptor Guanylyl Cyclase-A in Myocardial Infarction Evaluated Using Genetically Engineered Mice

K. Nakao, A. Fukamizu, K. Tanimoto, 2005, Hypertension.

IS040 Positive association between essential hypertension and Glu298Asp polymorphism in the endothelial nitric oxide synthase gene

K. Nakao, I. Masuda, Yoshihiko Saito, 1998 .