J. Juarez

发表

Regulation of u‐PA gene expression in human prostate cancer

J. Yang, M. Dall’Era, C. Evans, 2001, International journal of cancer.

Inhibition of angiogenesis by two-chain high molecular weight kininogen (HKa) and kininogen-derived polypeptides.

R. Sakthivel, A. Mazar, K. McCrae, 2002, Canadian journal of physiology and pharmacology.

Role and regulation of expression of 92‐kDa type‐IV collagenase (MMP‐9) in 2 invasive squamous‐cell‐carcinoma cell lines of the oral cavity

G. Nicolson, H. Saya, G. Clayman, 1993, International journal of cancer.

Copper Binding by Tetrathiomolybdate Attenuates Angiogenesis and Tumor Cell Proliferation through the Inhibition of Superoxide Dismutase 1

D. Shaw, A. Mazar, F. Doñate, 2006, Clinical Cancer Research.

Requirement of an Upstream AP-1 Motif for the Constitutive and Phorbol Ester-inducible Expression of the Urokinase-type Plasminogen Activator Receptor Gene*

D. Boyd, W. Doe, C. Pfarr, 1996, The Journal of Biological Chemistry.

Identification of biomarkers for the antiangiogenic and antitumour activity of the superoxide dismutase 1 (SOD1) inhibitor tetrathiomolybdate (ATN-224)

D. Shaw, A. Mazar, F. Doñate, 2008, British Journal of Cancer.

Peptides Derived from the Histidine-Proline Domain of the Histidine-Proline-Rich Glycoprotein Bind to Tropomyosin and Have Antiangiogenic and Antitumor Activities

D. Shaw, A. Mazar, F. Doñate, 2004, Cancer Research.

Stimulation of 92-kDa Gelatinase B Promoter Activity by ras Is Mitogen-activated Protein Kinase Kinase 1-independent and Requires Multiple Transcription Factor Binding Sites Including Closely Spaced PEA3/ets and AP-1 Sequences (*)

E. Lengyel, H. Sato, D. Boyd, 1996, The Journal of Biological Chemistry.

The discovery of kinase inhibitors by a combination of diversity-oriented synthesis and selective screening

A. Mazar, F. Doñate, R. Ternansky, 2016 .

Synthesis and evaluation of multisubstrate bicyclic pyrimidine nucleoside inhibitors of human thymidine phosphorylase.

B. Ganem, D. Shaw, Weiru Wang, 2006, Journal of medicinal chemistry.

Discovery of (R,E)-N-(7-Chloro-1-(1-[4-(dimethylamino)but-2-enoyl]azepan-3-yl)-1H-benzo[d]imidazol-2-yl)-2-methylisonicotinamide (EGF816), a Novel, Potent, and WT Sparing Covalent Inhibitor of Oncogenic (L858R, ex19del) and Resistant (T790M) EGFR Mutants for the Treatment of EGFR Mutant Non-Small-Ce

Chun Xing Li, S. Bender, G. Spraggon, 2016, Journal of medicinal chemistry.

Design of novel N-(2,4-dioxo-1,2,3,4-tetrahydro-thieno[3,2-d]pyrimidin-7-yl)-guanidines as thymidine phosphorylase inhibitors, and flexible docking to a homology model.

W. Guida, F. Doñate, R. Ternansky, 2003, Bioorganic & medicinal chemistry letters.

Overcoming EGFR T790M and C797S resistance with mutant-selective allosteric inhibitors

Haikuo Zhang, Gerald Lelais, Kwok-Kin Wong, 2016 .

The antiangiogenic activity of cleaved high molecular weight kininogen is mediated through binding to endothelial cell tropomyosin

N. Ziats, Y. Pang, A. Mazar, 2002, Proceedings of the National Academy of Sciences of the United States of America.

EGF816 Exerts Anticancer Effects in Non-Small Cell Lung Cancer by Irreversibly and Selectively Targeting Primary and Acquired Activating Mutations in the EGF Receptor.

J. Barretina, Jennifer L. Harris, J. Engelman, 2016, Cancer research.

HTRF Kinase Assay Development and Methods in Inhibitor Characterization.

J. Juarez, Yong Jia, M. Manuia, 2016, Methods in molecular biology.

Identification of a New Epitope in uPAR as a Target for the Cancer Therapeutic Monoclonal Antibody ATN-658, a Structural Homolog of the uPAR Binding Integrin CD11b (αM)

T. O’Halloran, A. Mazar, Liqing Chen, 2014, PloS one.

Transcriptional activation of the urokinase receptor gene in invasive colon cancer

J. Skibber, D. Boyd, J. Juarez, 1994, International journal of cancer.

Histidine-Proline Rich Glycoprotein (HPRG) binds and transduces anti-angiogenic signals through cell surface tropomyosin on endothelial cells

D. Shaw, A. Mazar, K. McCrae, 2004, Thrombosis and Haemostasis.

Regulation of urokinase‐type plasminogen activator expression by an ERK1‐dependent signaling pathway in a squamous cell carcinoma cell line

E. Lengyel, D. Boyd, J. Juarez, 1996, Journal of cellular biochemistry.

Histidine-proline-rich glycoprotein has potent antiangiogenic activity mediated through the histidine-proline-rich domain.

D. Shaw, A. Mazar, G. Parry, 2002, Cancer research.

Superoxide dismutase 1 (SOD1) is essential for H2O2-mediated oxidation and inactivation of phosphatases in growth factor signaling

D. Shaw, A. Mazar, N. Tonks, 2008, Proceedings of the National Academy of Sciences.

Abstract 1734:In vitrocharacterization of EGF816, a third-generation mutant-selective EGFR inhibitor

Jennifer L. Harris, S. Bender, N. Pathan, 2014 .

Effect of PD 098059, a specific inhibitor of mitogen-activated protein kinase kinase, on urokinase expression and in vitro invasion.

G. Nicolson, D. Boyd, C. Simon, 1996, Cancer research.

Regulation of 92 kDa type IV collagenase expression by the jun aminoterminal kinase- and the extracellular signal-regulated kinase-dependent signaling cascades

E. Lengyel, D. Boyd, J. Juarez, 1997, Oncogene.