M. Meikle

发表

Immunolocalization of collagenase and tissue inhibitor of metalloproteinases (TIMP) in mechanically deformed fibrous joints.

R. Hembry, J. Reynolds, S. Atkinson, 1990, American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics.

The use of in vitro models for investigating the response of fibrous joints to tensile mechanical stress.

J. Reynolds, J. Heath, M. Meikle, 1984, American journal of orthodontics.

Micro-vibrations at 30 Hz on bone cells cultivated in vitro produce soluble factors for osteoclast inhibition and osteoblast activity.

M. Meikle, S. García-López, R. Villanueva, 2019, Archives of oral biology.

Calcium waves in fluid flow stimulated osteoblasts are G protein mediated.

W. Mason, F. McDonald, M. Meikle, 1996, Archives of biochemistry and biophysics.

Rabbit bone collagenase inhibitor blocks the activity of other neutral metalloproteinases.

J. Reynolds, G. Murphy, M. Meikle, 1979, Biochemical and biophysical research communications.

Immunolocalization of matrix metalloproteinases and TIMP-1 (tissue inhibitor of metalloproteinases) in human gingival tissues from periodontitis patients.

R. Hembry, J. Reynolds, C. Horton, 1994, Journal of periodontal research.

The effects of selective inhibitors of matrix metalloproteinases (MMPs) on bone resorption and the identification of MMPs and TIMP-1 in isolated osteoclasts.

R. Hembry, J. Reynolds, G. Murphy, 1994, Journal of cell science.

Remodeling the Dentofacial Skeleton : The Biological Basis of Orthodontics and Dentofacial Orthopedics

M. Meikle, M. Meikle, M. C. Meikle, 2006 .

Stromelysin (MMP‐3) Synthesis Is Up‐Regulated in Estrogen‐Deficient Mouse Osteoblasts In Vivo and In Vitro

A. Tumber, R. Hembry, J. Reynolds, 1999, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Human breast‐cancer cells stimulate the fusion, migration and resorptive activity of osteoclasts in bone explants

A. Tumber, M. Meikle, H. Morgan, 2001, International journal of cancer.

An analysis of Ca2+ release by DGEA: mobilization of two functionally distinct internal stores in Saos-2 cells.

W. Mason, F. McDonald, M. Meikle, 1998, American journal of physiology. Cell physiology.

Autocrine signals promote osteoblast survival in culture.

A. Tumber, M. Meikle, P. Hill, 2000, The Journal of endocrinology.

Bone-derived growth factors modulate collagenase and TIMP (tissue inhibitor of metalloproteinases) activity and type I collagen degradation by mouse calvarial osteoblasts.

B. Thomson, J. Reynolds, M. Meikle, 1991, Bone and mineral.

Interleukin-2, interleukin-2 receptor and interleukin-4 levels are elevated in the sera of patients with periodontal disease.

M. Meikle, C. McFarlane, C. G. McFarlane, 1991, Journal of periodontal research.

The release of interleukin‐1β, tumor necrosis factor‐α and i nterferon‐γ by cultured peripheral blood mononuclear cells from patient swith periodontitis

J. Reynolds, M. Meikle, C. McFarlane, 1990 .

Gingival fibroblasts degrade type I collagen films when stimulated with tumor necrosis factor and interleukin 1: evidence that breakdown is mediated by metalloproteinases.

J. Reynolds, G. Murphy, S. Atkinson, 1989, Journal of periodontal research.

Alterations in the Synthesis of IL-1β, TNF-α, IL-6, and Their Downstream Targets RANKL and OPG by Mouse Calvarial Osteoblasts In vitro: Inhibition of Bone Resorption by Cyclic Mechanical Strain

M. Meikle, S. García-López, R. Villanueva, 2013, Front. Endocrinol..

Induction of osteopenia during experimental tooth movement in the rat: alveolar bone remodelling and the mechanostat theory.

I. Ichim, B. Patel, T. Milne, 2009, European journal of orthodontics.

Osteoblasts mediate insulin-like growth factor-I and -II stimulation of osteoclast formation and function.

J. Reynolds, M. Meikle, P. Hill, 1995, Endocrinology.

Pig interleukin 1 (Catabolin) is a potent stimulator of bone resorptionin vitro

J. Saklatvala, J. Reynolds, S. Atkinson, 2007, Calcified Tissue International.

Collagenase and collagenase inhibitor levels following changes in bone resorption in vitro

J. Reynolds, M. Meikle, A. Sellers, 2006, Calcified Tissue International.

The cellular actions of interleukin-11 on bone resorption in vitro.

A. Tumber, M. Meikle, P. Hill, 1998, Endocrinology.

Cytokines, matrix metalloproteinases and tissue inhibitor of metalloproteinases‐1 in gingival crevicular fluid from patients with Papillon‐Lefèvre syndrome

J. Reynolds, S. Twetman, M. Meikle, 2004, Acta odontologica Scandinavica.

Matrix metallproteinases and TIMP‐1 localization at sites of osteogenesis in the craniofacial region of the rabbit embryo

R. Hembry, J. Reynolds, M. Meikle, 1995, The Anatomical record.

Rabbit calvarial osteoblasts in culture constitutively synthesize progelatinase-A, and TIMP-1 and TIMP-2.

R. Hembry, J. Reynolds, M. Meikle, 1994, Biochimica et biophysica acta.

Regional and temporal changes in the synthesis of matrix metalloproteinases and TIMP-1 during development of the rabbit mandibular condyle.

R. Hembry, J. Reynolds, M. Meikle, 1994, Journal of anatomy.

Inhibition of stimulated bone resorption in vitro by TIMP-1 and TIMP-2.

J. Reynolds, M. Meikle, P. Hill, 1993, Biochimica et biophysica acta.

Stimulation of bone resorption in vitro by a non-prostanoid factor released by human monocytes in culture.

J. Reynolds, M. Gowen, M. Meikle, 1983, Biochimica et biophysica acta.

Advances in understanding cell interactions in tissue resorption. Relevance to the pathogenesis of periodontal diseases and a new hypothesis.

J. Reynolds, J. Heath, M. Meikle, 1986, Journal of oral pathology.

Altered serum levels of the osteoclast-specific TRACP 5b isoform in Chinese children undergoing orthodontic treatment.

J. Maclaine, R. Wong, B. Rabie, 2013, European journal of orthodontics.

The purification and partial characterization of bone resorptive polypeptides from bovine bone matrix.

J. Reynolds, M. Meikle, P. Hill, 1994, Biochimica et biophysica acta.

The synthesis of collagenase, gelatinase-A (72 kDa) and -B (95 kDa), and TIMP-1 and -2 by human osteoblasts from normal and arthritic bone.

R. Hembry, J. Reynolds, S. Bord, 1995, Bone.

The Synthesis of Collagenase, (95 kDa), and TIMP-1 and -2 Normal and Arthritic Bone Gelatinase-A (72 kDa) and -B by Human Osteoblasts From

R. Hembry, J. Reynolds, S. Bord, 1995 .

Rabbit cranial suture fibroblasts under tension express a different collagen phenotype.

R. Hembry, J. Reynolds, J. Heath, 1982, Archives of oral biology.

Neutral metallo-proteinases of rabbit bone. Separation in latent forms of distinct enzymes that when activated degrade collagen, gelatin and proteoglycans.

J. Reynolds, M. Meikle, A. Sellers, 1978, The Biochemical journal.

Pertussis toxin‐sensitive activation of phospholipase A2 can be resolved from phosphoinositidase C in primary cultures of mouse osteoblasts using indomethacin

R. Farndale, M. Meikle, J. Sandy, 1993, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Leukotriene B4 increases intracellular calcium concentration and phosphoinositide metabolism in mouse osteoblasts via cyclic adenosine 3',5'-monophosphate-independent pathways.

M. Meikle, J. Sandy, B. Martin, 1991, Endocrinology.

Effect of tensile mechanical stress on the synthesis of metalloproteinases by rabbit coronal sutures in vitro

J. Reynolds, M. Meikle, A. Sellers, 2006, Calcified Tissue International.

Human gingival tissues in culture synthesize three metalloproteinases and a metalloproteinase inhibitor.

J. Reynolds, J. Heath, M. Gowen, 1982, Journal of periodontal research.

Effect of streptococcal cell wall components on bone metabolism in vitro

J. Reynolds, M. Gowen, M. Meikle, 1982, Calcified Tissue International.

Biochemical and autoradiographical evidence that anterior mandibular displacement in the young growing rat does not stimulate cell proliferation or matrix formation at the mandibular condyle.

J. Heath, M. Meikle, D. Tewson, 1988, Archives of oral biology.

Anterior mandibular displacement and condylar growth. An experimental study in the rat.

J. Heath, M. Meikle, E. A. Tonge, 1982, American journal of orthodontics.

Mouse osteoblasts synthesize collagenase in response to bone resorbing agents.

J. Reynolds, J. Heath, S. Atkinson, 1984, Biochimica et biophysica acta.

Rabbit cranial sutures in vitro: A new experimental model for studying the response of fibrous joints to mechanical stress

J. Dingle, J. Reynolds, M. Meikle, 1979, Calcified Tissue International.

The effects of serine proteinase inhibitors on bone resorption in vitro.

A. Tumber, J. Reynolds, M. Meikle, 2003, The Journal of endocrinology.

Preliminary characterization of porcine bone marrow stromal cells: Skeletogenic potential, colony‐forming activity, and response to dexamethasone, transforming growth factor β, and basic fibroblast growth factor

B. Thomson, N. Loveridge, J. Triffitt, 1993, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

The tissue, cellular, and molecular regulation of orthodontic tooth movement: 100 years after Carl Sandstedt.

Murray C Meikle, M. Meikle, 2005, European journal of orthodontics.

Re-examination of 'Einige Beitrage zur Theorie der Zahnregulierung' (Some contributions to the theory of the regulation of teeth) published in 1904-1905 by Carl Sandstedt.

Dirk Bister, Murray C Meikle, D. Bister, 2013, European journal of orthodontics.

The dentomaxillary complex and overjet correction in Class II, division 1 malocclusion: objectives of skeletal and alveolar remodeling.

M. Meikle, 1980, American journal of orthodontics.

On the transplantation, regeneration and induction of bone: the path to bone morphogenetic proteins and other skeletal growth factors.

M. Meikle, 2007, The surgeon : journal of the Royal Colleges of Surgeons of Edinburgh and Ireland.

Effect of poly DL-lactide--co-glycolide implants and xenogeneic bone matrix-derived growth factors on calvarial bone repair in the rabbit.

P. Speight, S. Watt-Smith, J. Reynolds, 1994, Biomaterials.

Resorbable synthetic polymers as replacements for bone graft.

A. Coombes, M. Meikle, A.G.A. Coombes, 1994, Clinical materials.

Northcroft Memorial Lecture 2007. A Century of Progress: Advances in Orthodontics since the Foundation of the British Society for the Study of Orthodontics

M. Meikle, 2008, Journal of orthodontics.

In vivo transplantation of the mandibular joint of the rat; an autoradiographic investigation into cellular changes at the condyle.

M. Meikle, 1973, Archives of oral biology.

Identification of matrix metalloproteinases and their inhibitor in the articular disc of the craniomandibular joint of the rabbit.

R. Hembry, J. Reynolds, M. Meikle, 1996, Archives of oral biology.

Mechanisms of connective tissue matrix destruction in periodontitis.

J. Reynolds, M. Meikle, 1997, Periodontology 2000.

Cultured human periodontal ligament cells constitutively express multiple osteotropic cytokines and growth factors, several of which are responsive to mechanical deformation.

K. Beggs, Murray C Meikle, Mark N Pinkerton, 2008, Journal of periodontal research.

Short periods of cyclic mechanical strain enhance triple-supplement directed osteogenesis and bone nodule formation by human embryonic stem cells in vitro.

T. Cao, Mingming Li, I. Islam, 2013, Tissue engineering. Part A.

The role of the condyle in the postnatal growth of the mandible.

M. Meikle, Murray C. Meikle, 1973, American journal of orthodontics.

A. Tumber, M. Meikle, P. Hill, 2022 .

Engineering the Periodontal Ligament in Hyaluronan – Gelatin – Type I Collagen Constructs : Upregulation of Apoptosis and Alterations in Gene Expression by Cyclic Compressive Strain

G. Sriram, T. Cao, M. Meikle, 2014 .

Engineering three-dimensional constructs of the periodontal ligament in hyaluronan-gelatin hydrogel films and a mechanically active environment.

T. Cao, M. Meikle, K. Vinoth, 2013, Journal of periodontal research.

Mechanical deformation inhibits IL-10 and stimulates IL-12 production by mouse calvarial osteoblasts in vitro.

F. Massó, L. Montaño, V. Ramírez-Amador, 2005, Archives of oral biology.

Inhibition of bone resorption in vitro by selective inhibitors of gelatinase and collagenase.

Morphy, J. Reynolds, J. O'Connell, 1995, The Biochemical journal.

Bacterial antigens induce collagenase and prostaglandin E2 synthesis in human gingival fibroblasts through a primary effect on circulating mononuclear cells

R. Hembry, J. Reynolds, J. Heath, 1987, Infection and immunity.

Recent advances in understanding mechanically induced bone remodeling and their relevance to orthodontic theory and practice.

J R Sandy, R W Farndale, M C Meikle, 1993, American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics.

Degradation of type I collagen films by mouse osteoblasts is stimulated by 1,25 dihydroxyvitamin D3 and inhibited by human recombinant TIMP (tissue inhibitor of metalloproteinases).

B. Thomson, J. Reynolds, S. Atkinson, 1987, Biochemical and biophysical research communications.

Guest editorial: what do prospective randomized clinical trials tell us about the treatment of class II malocclusions? A personal viewpoint.

M. Meikle, 2005, European journal of orthodontics.

Dentofacial remodelling produced by intermaxillary forces in Macaca mulatta.

D. Turpin, M. Meikle, C. D. Adams, 1972, Archives of oral biology.

The effect of a Class II intermaxillary force on the dentofacial complex in the adult Macaca mulatta monkey.

M. Meikle, 1970, American journal of orthodontics.

G-protein signalling pathways and oestrogen: a role of balanced maintenance in osteoblasts.

A. Tumber, F. McDonald, M. Meikle, 1999, Biochimica et biophysica acta.

The effect of cyclic mechanical strain on the expression of adhesion-related genes by periodontal ligament cells in two-dimensional culture.

T. Cao, T. Milne, M. Meikle, 2012, Journal of periodontal research.