J. Routes

James F. Jones, J. Bellanti, R. Gruchalla, 2005, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Pulmonary infection with Mycobacterium neoaurum identified by 16S ribosomal DNA sequence.

E. Chan, L. Heifets, J. Routes, 2007, The Journal of infection.

Expression of human herpesvirus 8 in primary pulmonary hypertension.

K. Brown, N. Voelkel, R. Tuder, 2003, The New England journal of medicine.

The Wisconsin Approach to Newborn Screening for Severe Combined Immunodeficiency

T. Fleisher, J. Verbsky, M. Thakar, 2012, Pediatrics.

Newborn Screening for Severe Combined Immunodeficiency; The Wisconsin Experience (2008–2011)

W. Grossman, J. Verbsky, Sreelatha T. Reddy, 2011, Journal of Clinical Immunology.

All together to Fight COVID-19

L. Uddin, M. Perc, W. Al-Herz, 2020, The American Journal of Tropical Medicine and Hygiene.

Association of Persistent Rubella Virus With Idiopathic Skin Granulomas in Clinically Immunocompetent Adults.

K. Sullivan, O. Sokumbi, E. Abernathy, 2022, JAMA dermatology.

Granulomatous and lymphocytic interstitial lung disease diagnosed by transbronchial lung cryobiopsy.

B. Benn, J. Routes, J. Kurman, 2020, Cryobiology.

Granulomatous and Lymphocytic Interstitial Lung Disease (GLILD): A Spectrum of Pulmonary Histopathological Lesions in Common Variable Immunodeficiency (CVID) - Histological and Immunohistochemical Analysis of 16 cases

J. Routes, Nagarjun Rao, A. C. Mackinnon, 2015 .

Granulomatous and lymphocytic interstitial lung disease: a spectrum of pulmonary histopathologic lesions in common variable immunodeficiency--histologic and immunohistochemical analyses of 16 cases.

A. Mackinnon, J. Routes, Nagarjun Rao, 2015, Human pathology.

Isoforms into Multiple Distinct IL12RB1 Human Inflammatory Signals Direct Expression of

Halli E. Miller, J. Waukau, J. Routes, 2012 .

Granulomatous-lymphocytic lung disease shortens survival in common variable immunodeficiency.

D. Lynch, K. Brown, C. Cool, 2004, The Journal of allergy and clinical immunology.

X-linked agammaglobulinemia (XLA): Phenotype, diagnosis, and therapeutic challenges around the world

A. Plebani, C. Pignata, H. Kanegane, 2019, The World Allergy Organization Journal.

Possible role of human herpesvirus 8 in the lymphoproliferative disorders in common variable immunodeficiency

K. Brown, W. Wheat, C. Cool, 2005, The Journal of experimental medicine.

Rituximab and antimetabolite treatment of granulomatous and lymphocytic interstitial lung disease in common variable immunodeficiency.

J. Verbsky, P. Simpson, C. Cool, 2020, The Journal of allergy and clinical immunology.

Immunodeficiency Presenting as an Undiagnosed Disease.

J. Verbsky, J. Routes, 2017, Pediatric clinics of North America.

International Consensus Document (ICON): Common Variable Immunodeficiency Disorders.

C. Cunningham-Rundles, M. Tang, F. Bonilla, 2016, The journal of allergy and clinical immunology. In practice.

Current Perspectives ICON : Common Variable Immunodeficiency Disorders

C. Cunningham-Rundles, F. Bonilla, S. Nonoyama, 2015 .

ICON: Common Variable Immunodeficiency Disorders

C. Cunningham-Rundles, M. Tang, F. Bonilla, 2015 .

Granulomatous-lymphocytic interstitial lung disease in a patient with common variable immunodeficiency.

P. Lieberman, J. Routes, 2014, Journal of Allergy and Clinical Immunology: In Practice.

Management of Autoimmunity and Inflammation

J. Verbsky, J. Routes, 2014 .

Common variable immunodeficiency

J. Routes, J. Tam, 2013, American journal of rhinology & allergy.

Granulomatous disease in common variable immunodeficiency

J. Routes, Y. Morimoto, 2005, Current allergy and asthma reports.

Uncommon conundrum in common variable immunodeficiency.

C. Cunningham-Rundles, K. Sullivan, J. Routes, 2005, Clinical immunology.

Hypersensitivity pneumonitis in a patient with hypogammaglobulinemia.

J. Routes, P. Schkade, 1996, The Journal of allergy and clinical immunology.

Lack of correlation between Chlamydia pneumoniae antibody titers and adult-onset asthma.

H. Nelson, J. Routes, J. Noda, 2000, The Journal of allergy and clinical immunology.

Dose dependence and time course of the immunologic response to administration of standardized cat allergen extract.

M. O'connor, S. Dreskin, W. Wheat, 2004, The Journal of allergy and clinical immunology.

Development of a routine newborn screening protocol for severe combined immunodeficiency.

R. Laessig, W. Grossman, M. Katcher, 2009, The Journal of allergy and clinical immunology.

Newborn Screening for Severe Combined Immunodeficiency

J. Verbsky, J. Routes, 2013, Current Allergy and Asthma Reports.

CTLA4 Message Reflects Pathway Disruption in Monogenic Disorders and Under Therapeutic Blockade

Ryan M. Baxter, M. McCarter, J. Verbsky, 2019, Front. Immunol..

Low Serum IgE Is a Sensitive and Specific Marker for Common Variable Immunodeficiency (CVID)

C. Cunningham-Rundles, K. Sullivan, R. Fuleihan, 2018, Journal of Clinical Immunology.

Allergic manifestations of inborn errors of immunity and their impact on the diagnosis: A worldwide study

C. Pignata, W. Al-Herz, D. El-Ghoneimy, 2022, The World Allergy Organization journal.

Antibiotic Use After Removal of Penicillin Allergy Label

E. Phillips, D. Brousseau, M. Castells, 2018, Pediatrics.

Possible Role of Arginase-1 in Concomitant Tumor Immunity

J. Routes, Michael Korrer, 2014, PloS one.

Autosomal Dominant Hyper-IgE Syndrome in the USIDNET Registry.

C. Cunningham-Rundles, S. Holland, H. Ochs, 2017, The journal of allergy and clinical immunology. In practice.

IFN increases class I MHC antigen expression on adenovirus-infected human cells without inducing resistance to natural killer cell killing.

J. Routes, 1992, Journal of immunology.

All together to Fight Novel Coronavirus Disease (COVID-19).

L. Uddin, M. Perc, W. Al-Herz, 2020, The American journal of tropical medicine and hygiene.

Implementing Routine Testing for Severe Combined Immunodeficiency within Wisconsin's Newborn Screening Program

R. Laessig, W. Grossman, J. Verbsky, 2010, Public health reports.

Anti-adenovirus type 5 cytotoxic T lymphocytes: immunodominant epitopes are encoded by the E1A gene

F. Graham, D. Bellgrau, J. Routes, 1991, Journal of virology.

Damaging BTK Variant Demonstrated by Carrier, Allele-Specific BTK Expression in B Cells and Monocytes

J. Verbsky, J. Routes, M. Hintermeyer, 2019, Journal of Clinical Immunology.

CREB (cAMP response element binding protein) and C/EBPalpha (CCAAT/enhancer binding protein) are required for the superstimulation of phosphoenolpyruvate carboxykinase gene transcription by adenoviral E1a and cAMP.

D. Klemm, J. Routes, S. Ryan, 2000, The Biochemical journal.

Long‐term outcomes of 176 patients with X‐linked hyper‐IgM syndrome treated with or without hematopoietic cell transplantation

L. Notarangelo, J. Chou, C. Cunningham-Rundles, 2017, The Journal of allergy and clinical immunology.

Adenovirus serotype 5 E1A expressing tumor cells elicit a tumor-specific CD8+ T cell response independent of NKG2D

J. Routes, Michael Korrer, 2015, Results in immunology.

Adenovirus serotype 5 E1A sensitizes tumor cells to NKG2D-dependent NK cell lysis and tumor rejection

L. Lanier, A. Cerwenka, K. Morris, 2005, The Journal of experimental medicine.

Newborn Screening for Severe Combined Immunodeficiency-A History of the TREC Assay

J. Verbsky, J. Routes, M. Bausch-Jurken, 2017 .

Corticosteroids in inflammatory bowel disease. A review.

H. Claman, J. Routes, 1987, Journal of clinical gastroenterology.

Adenovirus E1A, Not Human Papillomavirus E7, Sensitizes Tumor Cells to Lysis by Macrophages Through Nitric Oxide- and TNF-α-Dependent Mechanisms Despite Up-Regulation of 70-kDa Heat Shock Protein1

K. Morris, Tanya A. Miura, J. Routes, 2003, The Journal of Immunology.

Adenovirus E1A Proteins Regulate Phosphoenolpyruvate Carboxykinase Gene Transcription through Multiple Mechanisms (*)

D. Klemm, J. Routes, S. Ryan, 1996, The Journal of Biological Chemistry.

Endogenous expression of E1A in human cells enhances the effect of adenovirus E3 on class I major histocompatibility complex antigen expression

J. Routes, J. L. Cook, B. A. Metz, 1993, Journal of virology.

Resistance of human cells to the adenovirus E3 effect on class I MHC antigen expression. Implications for antiviral immunity.

J. Routes, J. L. Cook, J. Cook, 1990, Journal of immunology.

Cause of Death in Neonates with Inconclusive or Abnormal T-cell Receptor Excision Circle Assays on Newborn Screening

J. Verbsky, C. Brokopp, M. Baker, 2011, Journal of Clinical Immunology.

T-cell Receptor Excision Circles of Newborns Are Associated with Gestational Age: Data from Wisconsin Newborn Screening for Severe Combined Immunodeficiency

M. Lindstrom, W. Grossman, C. Seroogy, 2011 .

Practice parameter for the diagnosis and management of primary immunodeficiency.

S. Spector, J. Orange, R. Nelson, 2015, The Journal of allergy and clinical immunology.

Omenn Syndrome Identified by Newborn Screening.

J. Routes, M. Tallar, 2020, Clinics in perinatology.

Practice parameter for the diagnosis and management of primary immunodeficiency.

S. Spector, J. Orange, R. Nelson, 2005, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Rubella persistence in epidermal keratinocytes and granuloma M2 macrophages in patients with primary immunodeficiencies.

H. Ochs, K. Sullivan, F. Bonilla, 2016, The Journal of allergy and clinical immunology.

Macrophages Kill Human Papillomavirus Type 16 E6-Expressing Tumor Cells by Tumor Necrosis Factor Alpha- and Nitric Oxide-Dependent Mechanisms

M. Ellison, K. Morris, J. Routes, 2005, Journal of Virology.

Making a definitive diagnosis: Successful clinical application of whole exome sequencing in a child with intractable inflammatory bowel disease

David P Bick, David P Dimmock, Ulrich Broeckel, 2011, Genetics in Medicine.

Gain of Function Mutations of PIK3CD as a Cause of Primary Sclerosing Cholangitis

S. Rosenzweig, J. Verbsky, J. Niemela, 2014, Journal of Clinical Immunology.

Constrained chromatin accessibility in PU.1-mutated agammaglobulinemia patients

Ivan K. Chinn, J. Lupski, S. Grant, 2021, The Journal of experimental medicine.

Heterogeneity of human bone marrow and blood natural killer cells defined by single-cell transcriptome

J. Verbsky, S. Malarkannan, M. Riese, 2019, Nature Communications.

Human IL12RB1 expression is allele-biased and produces a novel IL12 response regulator

U. Broeckel, A. Turner, J. Routes, 2018, Genes & Immunity.

Newborn screening for SCID: where are we now?

J. Verbsky, Becky J. Buelow, J. Routes, 2014, Expert review of clinical immunology.

Activities of superoxide dismutases and NADPH oxidase in neutrophils obtained from asthmatic and normal donors

John M. Routes, Larry Borish, L. Borish, 1993, Inflammation.

92 – Pulmonary Complications of Primary Immunodeficiencies

J. Routes, 2016 .

Studies on nicotinic acetylcholine receptors in mammalian brain. Preliminary characterization of membrane-bound alpha-bungarotoxin receptors in rat cerebral cortex.

P. Salvaterra, A. D. de Blas, H. Mahler, 1976, The Journal of biological chemistry.

Screening for severe combined immunodeficiency in neonates

J. Verbsky, J. Routes, J. Tam, 2013, Clinical epidemiology.

ICON: The Early Diagnosis of Congenital Immunodeficiencies

J. B. Oliveira, F. Deist, C. Picard, 2014, Journal of Clinical Immunology.

IRAK4 Deficiency in a Patient with Recurrent Pneumococcal Infections: Case Report and Review of the Literature

J. Casanova, C. Picard, B. Boisson, 2017, Front. Pediatr..

Multiplexed quantitative real-time PCR to detect 22q11.2 deletion in patients with congenital heart disease.

U. Broeckel, W. Grossman, P. Simpson, 2010, Physiological genomics.

The Lung in Primary Immunodeficiencies: New Concepts in Infection and Inflammation

P. Soler-Palacín, S. Jolles, U. Baumann, 2018, Front. Immunol..

Chronic Granulomatous Disease-Associated IBD Resolves and Does Not Adversely Impact Survival Following Allogeneic HCT

L. Notarangelo, J. Puck, T. Torgerson, 2019, Journal of Clinical Immunology.

Newborn screening for SCID: three years of experience

J. Verbsky, J. Routes, N. Chase, 2011, Annals of the New York Academy of Sciences.

Global study of primary immunodeficiency diseases (PI)—diagnosis, treatment, and economic impact: an updated report from the Jeffrey Modell Foundation

J. Orange, L. Notarangelo, D. Lewis, 2011, Immunologic research.

Characterization of Crohn disease in X-linked inhibitor of apoptosis-deficient male patients and female symptomatic carriers.

Smita Y. Patel, A. Fischer, J. Hugot, 2014, The Journal of allergy and clinical immunology.

Novel Hemizygous IL2RG p.(Pro58Ser) Mutation Impairs IL-2 Receptor Complex Expression on Lymphocytes Causing X-Linked Combined Immunodeficiency

J. Kere, S. Mustjoki, M. Varjosalo, 2020, Journal of Clinical Immunology.

The introduction of RNA-DNA differences underlies interindividual variation in the human IL12RB1 mRNA repertoire

Halli E. Miller, U. Broeckel, A. Turner, 2015, Proceedings of the National Academy of Sciences.

PIDD-dependent activation of caspase-2-mediated mitochondrial injury in E1A-induced cellular sensitivity to macrophage nitric oxide-induced apoptosis

J. Radke, J. Routes, Iris Figueroa, 2018, Cell Death Discovery.

Inflammatory Signals Direct Expression of Human IL12RB1 into Multiple Distinct Isoforms

Halli E. Miller, J. Waukau, J. Routes, 2012, The Journal of Immunology.

Adenovirus E1A inhibits IFN-induced resistance to cytolysis by natural killer cells.

J. Routes, 1993, Journal of immunology.

Immunodeficiency overview.

J. Routes, Y. Morimoto, 2008, Primary care.

Recommendations for live viral and bacterial vaccines in immunodeficient patients and their close contacts.

J. Orange, L. Notarangelo, C. Cunningham-Rundles, 2014, The Journal of allergy and clinical immunology.

X-linked Hyper IgM Syndrome Presenting as Pulmonary Alveolar Proteinosis

H. Ochs, T. Torgerson, J. Verbsky, 2016, Journal of Clinical Immunology.

Sarcoidosis and Common Variable Immunodeficiency: Similarities and Differences

J. Verbsky, J. Routes, 2014, Seminars in Respiratory and Critical Care Medicine.

Newborn screening for SCID: lessons learned

J. Verbsky, Becky J. Buelow, J. Routes, 2016, Expert review of hematology.

Use of Combination Chemotherapy for Treatment of Granulomatous and Lymphocytic Interstitial Lung Disease (GLILD) in Patients with Common Variable Immunodeficiency (CVID)

L. Goodman, J. Verbsky, P. Simpson, 2012, Journal of Clinical Immunology.

Lack of Clinical Hypersensitivity to Penicillin Antibiotics in Common Variable Immunodeficiency

C. Cunningham-Rundles, K. Sullivan, R. Fuleihan, 2016, Journal of Clinical Immunology.

Safety and Tolerability of Subcutaneous IgPro20 at High Infusion Parameters in Patients with Primary Immunodeficiency: Findings from the Pump-Assisted Administration Cohorts of the HILO Study

N. Patel, D. Vinh, V. Bonagura, 2021, Journal of Clinical Immunology.

Diffuse pulmonary infiltrates in hypogammaglobulinemia.

L. Borish, J. Matz, J. Routes, 1992, Annals of allergy.

Oral Amoxicillin Challenges in Low-Risk Children During a Pediatric Emergency Department Visit.

L. Pezzin, E. Phillips, D. Brousseau, 2020, The journal of allergy and clinical immunology. In practice.

Severe Combined Immune Deficiency: Newborn Screening

J. Verbsky, J. Routes, 2016 .

Screening newborns for primary T-cell immunodeficiencies: consensus and controversy

J. Verbsky, J. Routes, Deborah J. Accetta Pedersen, 2011, Expert review of clinical immunology.

The Use of Salmonella Typhim Vaccine to Diagnose Antibody Deficiency

J. Verbsky, S. Gauld, J. Routes, 2017, Journal of Clinical Immunology.

Newborn Screening for Severe Combined Immunodeficiency; The Wisconsin Experience (2008–2011)

W. Grossman, J. Verbsky, Sreelatha T. Reddy, 2012, Journal of Clinical Immunology.

A Practical Approach to Newborn Screening for Severe Combined Immunodeficiency Using the T Cell Receptor Excision Circle Assay

J. Verbsky, M. Thakar, J. Routes, 2017, Front. Immunol..

H. Ochs, B. Grimbacher, A. Filipovich, 2016, Journal of Clinical Immunology.

Dysregulated Lymphocyte Antigen Receptor Signaling in Common Variable Immunodeficiency with Granulomatous Lymphocytic Interstitial Lung Disease

Ryan M. Baxter, J. Verbsky, D. S. Kong, 2023, Journal of Clinical Immunology.

The Use of Salmonella Typhim Vaccine to Diagnose Antibody Deficiency

J. Verbsky, S. Gauld, J. Routes, 2017, Journal of Clinical Immunology.

Inhibition of IFN-stimulated gene expression and IFN induction of cytolytic resistance to natural killer cell lysis correlate with E1A-p300 binding.

H. Li, S. Bayley, D. Klemm, 1996, Journal of immunology.

E1A oncogene induced sensitization to NK cell induced apoptosis requires PIDD and Caspase-2

J. Radke, J. Routes, J. Cook, 2019, Cell Death Discovery.

PIDD-dependent activation of caspase-2-mediated mitochondrial injury in E1A-induced cellular sensitivity to macrophage nitric oxide-induced apoptosis

J. Radke, J. Routes, Iris Figueroa, 2018, Cell Death Discovery.

E1A Oncogene Enhancement of Caspase-2-Mediated Mitochondrial Injury Sensitizes Cells to Macrophage Nitric Oxide-Induced Apoptosis1

Z. Siddiqui, Tanya A. Miura, J. Radke, 2008, The Journal of Immunology.

Oxide-Induced Apoptosis Sensitizes Cells to Macrophage Nitric Caspase-2-Mediated Mitochondrial Injury

Z. Siddiqui, Tanya A. Miura, J. Radke, 2008 .

Faculty Opinions recommendation of Revisiting human IL-12Rβ1 deficiency: a survey of 141 patients from 30 countries.

J. Verbsky, J. Routes, 2011 .

The interaction of adenovirus E1A with p300 family members modulates cellular gene expression to reduce tumorigenicity

T. Potter, Tanya A. Miura, J. Routes, 2007, Journal of cellular biochemistry.

Adenovirus persistence in man. Defective E1A gene product targeting of infected cells for elimination by natural killer cells.

J. Routes, J. Cook, 1989, Journal of immunology.

Newborn Screening for Severe Combined Immunodeficiency

J. Verbsky, D. Randolph, J. Routes, 2013 .

Measuring the effect of newborn screening on survival after haematopoietic cell transplantation for severe combined immunodeficiency: a 36-year longitudinal study from the Primary Immune Deficiency Treatment Consortium

L. Notarangelo, J. Puck, T. Torgerson, 2023, The Lancet.

Newborn screening for T-cell deficiency

J. Verbsky, J. Routes, N. Chase, 2010, Current opinion in allergy and clinical immunology.

Newborn Screening for Severe Combined Immunodeficiency

J. Verbsky, J. Routes, 2018, Current Allergy and Asthma Reports.

Pulmonary disease associated with common variable immunodeficiency

K. Brown, J. Routes, C. Bates, 2002 .

Role of Natural Killer (NK) Cells in Immunity to Adenoviruses

J. Routes, 1999 .

Primary Immune Deficiency Treatment Consortium (PIDTC) report.

M. van der Burg, L. Notarangelo, H. Bobby Gaspar, 2014, The Journal of allergy and clinical immunology.

Abnormal T-Cell Receptor Excision Circle Newborn Screen: What Next?

J. Routes, B. Prince, 2018, The journal of allergy and clinical immunology. In practice.

Inflammatory Signals Direct Expression of Human IL12RB1 into Multiple Distinct Isoforms

Halli E. Miller, J. Waukau, J. Routes, 2012, The Journal of Immunology.

Salmonella Cervical Lymphadenitis in an Immunocompetent Child Exposed to a Snake at an Educational Exhibit: A Case Report

S. Kehl, P. Havens, P. Lye, 2012 .

Impaired Response to Polysaccharide Vaccine in Selective IgE Deficiency

J. Verbsky, M. Lawrence, L. Borish, 2023, Journal of Clinical Immunology.

Possible role of human herpesvirus 8 in the lymphoproliferative disorders in common variable immunodeficiency

K. Brown, W. Wheat, C. Cool, 2005, Journal of Experimental Medicine.

X-linked Hyper IgM Syndrome Presenting as Pulmonary Alveolar Proteinosis

H. Ochs, T. Torgerson, J. Verbsky, 2016, Journal of Clinical Immunology.