Changchang Liu

Exploring the understudied human kinome for research and therapeutic opportunities

Benjamin M. Gyori, John A. Bachman, Matthew E. Berginski, 2020, bioRxiv.

Molecular-docking-guided design and synthesis of new IAA-tacrine hybrids as multifunctional AChE/BChE inhibitors.

Zhi-Qiang Cheng, Luis Alexandre Muehlmann, Cheng-Shi Jiang, 2019, Bioorganic chemistry.

Multiomics Profiling Establishes the Polypharmacology of FDA-Approved CDK4/6 Inhibitors and the Potential for Differential Clinical Activity.

Sarah A. Boswell, P. Sorger, R. Everley, 2019, Cell chemical biology.

The Dark Kinase Knowledgebase: an online compendium of knowledge and experimental results of understudied kinases

Peter K. Sorger, Nienke Moret, Dennis Goldfarb, 2020, Nucleic Acids Res..

Multi-Omics Profiling Establishes the Polypharmacology of FDA Approved CSK4/6 Inhibitors and Its Impact on Drug Response

Sarah A. Boswell, P. Sorger, R. Everley, 2018 .

Design and synthesis of pregnenolone/2-cyanoacryloyl conjugates with dual NF-κB inhibitory and anti-proliferative activities.

Yuying Zhang, Hua Zhang, K. Zhu, 2017, Bioorganic & medicinal chemistry letters.

A Hybrid Structure-Based Machine Learning Approach for Predicting Kinase Inhibition by Small Molecules

Peter S. Kutchukian, P. Sorger, Mohammed AlQuraishi, 2023, J. Chem. Inf. Model..

Multi-omics profiling establishes the polypharmacology of FDA Approved CDK4/6 inhibitors and its impact on drug response

Sarah A. Boswell, P. Sorger, R. Everley, 2017, bioRxiv.