J. Abelson

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Point mutations in yeast U6 snRNA can specifically block the first or second step of pre-mRNA splicing in vitro

P. Fabrizio, J. Abelson, 2004, Molecular Biology Reports.

tRNA leucine identity and recognition sets.

J. Abelson, G. Tocchini-Valentini, M. Saks, 2000, Journal of molecular biology.

The yeast RNA gene products are essential for mRNA splicing in vitro

R. Lin, A. Lustig, J. Abelson, 1986, Cell.

PRP5: a helicase-like protein required for mRNA splicing in yeast.

J. Abelson, G. Dalbadie-McFarland, John Abelson, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Domains of yeast U4 spliceosomal RNA required for PRP4 protein binding, snRNP-snRNP interactions, and pre-mRNA splicing in vivo.

C. Guthrie, R. Bordonné, J. Banroques, 1990, Genes & development.

Mutations in conserved intron sequences affect multiple steps in the yeast splicing pathway, particularly assembly of the spliceosome.

C. Guthrie, J. Tamm, R. Parker, 1986, The EMBO journal.

Mutant tyrosine tRNA of altered amino acid specificity

H. Ozeki, Y. Shimura, J. Abelson, 1972, FEBS letters.

Substrate recognition and splice site determination in yeast tRNA splicing

V. M. Reyes, J. Abelson, 1988, Cell.

The subnuclear localization of tRNA ligase in yeast

M. W. Clark, J. Abelson, John Abelson, 1987, The Journal of cell biology.

Yeast tRNA ligase mutants are nonviable and accumulate tRNA splicing intermediates.

E. Phizicky, K. Nehrke, J. Abelson, 1992, The Journal of biological chemistry.

Mutations in the lactose operon caused by bacteriophage Mu.

R. Roberts, J. Abelson, E. Daniell, 1972, Journal of molecular biology.

Single Molecule Cluster Analysis dissects splicing pathway conformational dynamics

A. Laederach, Joshua S. Martin, N. Walter, 2015, Nature Methods.

A U5 small nuclear ribonucleoprotein particle protein involved only in the second step of pre-mRNA splicing in Saccharomyces cerevisiae

D. Horowitz, J. Abelson, 1993, Molecular and cellular biology.

PRP19: a novel spliceosomal component

T. Tsao, S. Cheng, W. Tarn, 1993, Molecular and cellular biology.

PRP18, a Protein Required fortheSecondReaction inPre-mRNASplicing

J. Abelson, U. Vijayraghavan, 1990 .

The anatomy of the T5 bacteriophage DNA molecule

C. A. Thomas, J. Abelson, 1966 .

The cloning of a T4 transfer RNA gene cluster.

J. Abelson, L. Gossens, K. Fukada, 1980, Journal of molecular biology.

Single Molecule Cluster Analysis Identifies Signature Dynamic Conformations along the Splicing Pathway

A. Laederach, Joshua S. Martin, N. Walter, 2016 .

Highly purified transfer RNA splicing endonuclease from Saccharomyces cerevisiae.

P. R. Green, J. Abelson, 1990, Methods in enzymology.

Novel activity of a yeast ligase deletion polypeptide. Evidence for GTP-dependent tRNA splicing.

C. Greer, S. Westaway, B. Apostol, 1993, The Journal of biological chemistry.

A restriction map of the T4 transfer RNA gene cluster.

J. Abelson, A. Otsuka, K. Fukada, 1980, Journal of molecular biology.

Bacteriophage T4 tRNA Leu .

J. Abelson, T. Pinkerton, G. Paddock, 1972, Nature: New biology.

The nucleotide sequences of tyrosine transfer RNAs of Escherichia coli.

H. Goodman, J. Smith, A. Landy, 1970, European journal of biochemistry.

Mutant tyrosine transfer ribonucleic acids

S. Brenner, L. Barnett, M. Gefter, 1969, Journal of molecular biology.

Mutant tyrosine transfer ribonucleic acids.

S. Brenner, L. Barnett, M. Gefter, 1970, FEBS letters.

Cloning of the Vibrio harveyi luciferase genes: use of a synthetic oligonucleotide probe.

M. Simon, K. Nealson, R. Ogden, 1983, Proceedings of the National Academy of Sciences of the United States of America.

Lac messenger RNA in lac Z gene mutants of Escherichia coli caused by insertion of bacteriophage Mu.

J. Abelson, E. Daniell, 1973, Journal of molecular biology.

RNA ligase in bacteria: Formation of a 2′,5′ linkage by an E. coli extract

C. Greer, B. Javor, J. Abelson, 1983, Cell.

Probing the Role of an Active Site Aspartic Acid in Dihydrofolate Reductase

S. Hecht, G. Komatsoulis, H. An, 1997 .

A synthetic substrate for tRNA splicing.

V. M. Reyes, J. Abelson, 1987, Analytical biochemistry.

Mutational analysis of the coordinate expression of the yeast tRNAArg-tRNAAsp gene tandem

V. M. Reyes, A. Newman, J. Abelson, 1986, Molecular and cellular biology.

Characterization of the inhomogeneous DNA in virions of bacteriophage Mu by DNA reannealing kinetics

D. Kohne, J. Abelson, E. Daniell, 1975, Journal of virology.

Bacteriophage Mu integration: on the orientation of the prophage.

J. Abelson, W. Boram, 1973, Virology.

Bacteriophage Mu integration: on the mechanism of Mu-induced mutations.

J. Abelson, W. Boram, 1971, Journal of molecular biology.

Specific hybridization of tyrosine transfer ribonucleic acids with DNA from a transducing bacteriophage phi-80 carrying the amber suppressor gene su 3.

H. Goodman, J. Smith, A. Landy, 1967, Journal of molecular biology.

The Saccharomyces cerevisiae PRP21 gene product is an integral component of the prespliceosome.

J. Abelson, J. Arenas, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Cloning of Beneckea genes in Escherichia coli

J. Abelson, A. Sarabhai, H. Lamfrom, 1978, Journal of bacteriology.

Summary of the genetic mapping of prophage Mu.

P. van de Putte, A. Toussaint, C. Wijffelman, 1973, Virology.

Mu-1 bacteriophage DNA.

J. Abelson, F. Torti, C. Barksdale, 1970, Virology.

Transcription in vitro of an isolated fragment of bacteriophage T4 genome.

A. Goldfarb, J. Abelson, J. Broida, 1982, Journal of molecular biology.

Requirement of the RNA helicase-like protein PRP22 for release of messenger RNA from spliceosomes

J. Abelson, M. Company, J. Arenas, 1991, Nature.

Binding interactions between yeast tRNA ligase and a precursor transfer ribonucleic acid containing two photoreactive uridine analogues.

N. Tanner, M. Hanna, J. Abelson, 1988, Biochemistry.

Duplicate genes for tyrosine transfer RNA in Escherichia coli.

S. Brenner, M. Gefter, J. Smith, 1970, Journal of molecular biology.

Amber Suppression: a Nucleotide Change in the Anticodon of a Tyrosine Transfer RNA

H. Goodman, S. Brenner, J. Smith, 1968, Nature.

Domain structure in yeast tRNA ligase.

D. Teplow, Terry D. Lee, T. Lee, 1990, Biochemistry.

Lariat structures are in vivo intermediates in yeast pre-mRNA splicing

H. Domdey, R. Lin, E. Brody, 1984, Cell.

SSB-1 of the yeast Saccharomyces cerevisiae is a nucleolar-specific, silver-binding protein that is associated with the snR10 and snR11 small nuclear RNAs

M. W. Clark, J. Abelson, J. Campbell, 1990, The Journal of cell biology.

The transfer RNA identity problem: a search for rules.

J R Sampson, M E Saks, J N Abelson, 1994, Science.

Changing the identity of a transfer RNA

R. Ogden, J. Normanly, J. Abelson, 1986, Nature.

Site-specific crosslinks of yeast U6 snRNA to the pre-mRNA near the 5' splice site.

J. Abelson, C. Kim, 1996, RNA.

Site-specific deoxynucleotide substitutions in yeast U 6 snRNA block splicing of pre-mRNA in vitro process of spliceosome

J. Abelson, T. Marciniec, Chang Hee Kim, 2013 .

The 5' and 3' domains of yeast U6 snRNA: Lsm proteins facilitate binding of Prp24 protein to the U6 telestem region.

S. Stevens, J. Abelson, D. E. Ryan, 2002, RNA.

The 5 9 and 3 9 domains of yeast U 6 snRNA : Lsm proteins facilitate binding of Prp 24 protein to the U 6 telestem region

S. Stevens, J. Abelson, D. E. Ryan, 2002 .

Site‐specific deoxynucleotide substitutions in yeast U6 snRNA block splicing of pre‐mRNA in vitro

J. Abelson, T. Marciniec, Chang Hee Kim, 1997, The EMBO journal.

Nucleotide sequence determination of bacteriophage T4 species I ribonucleic acid.

J. Abelson, G. Paddock, 1975, The Journal of biological chemistry.

Bacteriophage T4 transfer RNA. II. Mutants of T4 defective in the formation of functional suppressor transfer RNA.

J. H. Wilson, J. Abelson, 1972, Journal of molecular biology.

Bacteriophage T4 transfer RNA. 3. Clustering of the genes for the T4 transfer RNA's.

J. H. Wilson, J. Abelson, J. S. Kim, 1972, Journal of molecular biology.

Evidence for a base-pairing interaction between U6 small nuclear RNA and 5' splice site during the splicing reaction in yeast.

H. Sawa, J. Abelson, H. Sawa, 1992, Proceedings of the National Academy of Sciences of the United States of America.

The Yeast tRNA Splicing Endonuclease: A Tetrameric Enzyme with Two Active Site Subunits Homologous to the Archaeal tRNA Endonucleases

R. Rauhut, C. Ho, S. Stevens, 1997, Cell.

Composition and functional characterization of the yeast spliceosomal penta-snRNP.

Roger E. Moore, M. K. Young, Terry D. Lee, 2002, Molecular cell.

Characterization of U4 and U6 interactions with the 5' splice site using a S. cerevisiae in vitro trans-splicing system.

J. Abelson, T. L. Johnson, 2001, Genes & development.

An early hierarchic role of U1 small nuclear ribonucleoprotein in spliceosome assembly.

J. Abelson, S. Ruby, J. Abelson, 1988, Science.

Spliceosome assembly in yeast.

S. Cheng, J. Abelson, Soo-Chen Cheng, 1987, Genes & development.

Yeast mRNA splicing in vitro.

R. Lin, S. Cheng, A. Newman, 1985, The Journal of biological chemistry.

Pre-mRNA splicing in yeast.

S. Ruby, J. Abelson, 1991, Trends in genetics : TIG.

Two domains of yeast U6 small nuclear RNA required for both steps of nuclear precursor messenger RNA splicing

P. Fabrizio, J. Abelson, 1990, Science.

In vitro assembly of yeast U6 snRNP: a functional assay.

D. S. McPheeters, P. Fabrizio, J. Abelson, 1989, Genes & development.

Isolation and characterization of pre-mRNA splicing mutants of Saccharomyces cerevisiae.

M. Company, J. Abelson, U. Vijayraghavan, 1989, Genes & development.

Splicing of yeast nuclear pre-mRNA in vitro requires a functional 40S spliceosome and several extrinsic factors.

R. Lin, A. Lustig, J. Abelson, 1987, Genes & development.

spliceosome and several extrinsic factors

R. Lin, A. Lustig, J. Abelson, 1987 .

8 – Messenger RNA Splicing in Yeast

R. Lin, A. Lustig, J. Abelson, 1987 .

Molecular consequences of specific intron mutations on yeast mRNA splicing in vivo and in vitro

A. Newman, J. Abelson, Soo-Chen Cheng, 1985, Cell.

RNA splicing: rearrangement of RNA sequences in the expression of split genes

C. Greer, J. Abelson, 1984 .

In vitro reconstitution of functional yeast U2 snRNPs.

D. S. McPheeters, P. Fabrizio, J. Abelson, 1989, Genes & development.

The "spliceosome": yeast pre-messenger RNA associates with a 40S complex in a splicing-dependent reaction.

E. Brody, J. Abelson, 1985, Science.

Preparation and fractionation of yeast splicing extract.

R. Lin, S. Cheng, A. Newman, 1990, Methods in enzymology.

PRP4: a protein of the yeast U4/U6 small nuclear ribonucleoprotein particle

J. Banroques, J. Abelson, 1989, Molecular and cellular biology.

Mutational analysis of the yeast U2 snRNA suggests a structural similarity to the catalytic core of group I introns

D. S. McPheeters, J. Abelson, 1992, Cell.

Purification of the yeast U4/U6.U5 small nuclear ribonucleoprotein particle and identification of its proteins.

S. Stevens, J Abelson, S W Stevens, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Stages in the second reaction of pre-mRNA splicing: the final step is ATP independent.

D. Horowitz, J. Abelson, 1993, Genes & development.

PRP18, a protein required for the second reaction in pre-mRNA splicing

J. Abelson, U. Vijayraghavan, 1990, Molecular and cellular biology.

Yeast pre-mRNA Splicing Mutants

J. Abelson, U. Vijayraghavan, 1989 .

Fractionation and characterization of a yeast mRNA splicing extract.

S. Cheng, J. Abelson, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Crystal structure of a DEAD box protein from the hyperthermophile Methanococcus jannaschii.

Haiyang Li, R. M. Story, J. Abelson, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Directed mutagenesis of dihydrofolate reductase.

J. Kraut, R. Ogden, J. E. Villafranca, 1983, Science.

Transfer RNA synthesis in vitro.

D. Nierlich, J. Abelson, A. Sarabhai, 1973, Proceedings of the National Academy of Sciences of the United States of America.

Sequence of a RNA templated by the 3'-OH RNA terminus of defective interfering particles of vesicular stomatitis virus.

J. Holland, B. Semler, J. Abelson, 1978, Proceedings of the National Academy of Sciences of the United States of America.

The DEAH‐box protein PRP22 is an ATPase that mediates ATP‐dependent mRNA release from the spliceosome and unwinds RNA duplexes

A. Pyle, E. Jankowsky, J. Abelson, 1998, The EMBO journal.

Prp43: An RNA helicase-like factor involved in spliceosome disassembly.

J. Abelson, J. Arenas, 1997, Proceedings of the National Academy of Sciences of the United States of America.

New tertiary constraints between the RNA components of active yeast spliceosomes: a photo-crosslinking study.

J. Murray, P. Stockley, C. Adams, 2004, RNA.

tRNA gene transcription in yeast: Effects of specified base substitutions in the intragenic promoter

R. Ogden, A. Newman, J. Abelson, 1983, Cell.

Crystal structure and evolution of a transfer RNA splicing enzyme.

C. Trotta, J Abelson, C R Trotta, 1998, Science.

The conserved central domain of yeast U6 snRNA: importance of U2-U6 helix Ia in spliceosome assembly.

J. Abelson, D. E. Ryan, 2002, RNA.

Isolation of a temperature-sensitive mutant with an altered tRNA nucleotidyltransferase and cloning of the gene encoding tRNA nucleotidyltransferase in the yeast Saccharomyces cerevisiae.

J. Y. Chen, N. Martin, M. Aebi, 1990, The Journal of biological chemistry.

18S rRNA processing requires the RNA helicase-like protein Rrp3.

J. Abelson, C. O'Day, F. Chavanikamannil, 1996, Nucleic acids research.

Conformational dynamics of single pre-mRNA molecules during in vitro splicing

C. Guthrie, N. Walter, M. Ditzler, 2010, Nature Structural &Molecular Biology.

Biased Brownian ratcheting leads to pre-mRNA remodeling and capture prior to first-step splicing

C. Guthrie, N. Walter, M. Blanco, 2013, Nature Structural &Molecular Biology.

Yeast pre-mRNA splicing: methods, mechanisms, and machinery.

S. Stevens, J. Abelson, 2002, Methods in enzymology.

ATP requirement for Prp5p function is determined by Cus2p and the structure of U2 small nuclear RNA

M. Ares, G. Voeltz, J. Abelson, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Evolution of a transfer RNA gene through a point mutation in the anticodon.

J Abelson, J R Sampson, M E Saks, 1998, Science.

tRNA Splicing*

Hong Li, C. Trotta, J Abelson, 1998, The Journal of Biological Chemistry.

In vitro construction of bacteriophage lambda and plasmid DNA molecules containing DNA fragments from bacteriophage T4.

J. Velten, J. Abelson, K. Fukada, 1976, Gene.

Electron microscopic identification of the yeast spliceosome.

M. W. Clark, S. Goelz, J. Abelson, 1988, The EMBO journal.

Genetic MappingoftheInversion LoopinBacteriophage Mu DNA

J. Abelson, E. Daniell, 1973 .

Heteroduplex structures of bacteriophage Mu DNA.

N. Davidson, J. Abelson, E. Daniell, 1973, Virology.

Biochemical and genetic analyses of the U5, U6, and U4/U6 x U5 small nuclear ribonucleoproteins from Saccharomyces cerevisiae.

T D Lee, M. K. Young, Terry D. Lee, 2001, RNA.

Yeast tRNA-splicing endonuclease is a heterotrimeric enzyme.

R. Rauhut, P. R. Green, J. Abelson, 1990, The Journal of biological chemistry.

In Vitro Studies of the Prp9·Prp11·Prp21 Complex Indicate a Pathway for U2 Small Nuclear Ribonucleoprotein Activation*

J. Abelson, D. Wiest, C. O'Day, 1996, The Journal of Biological Chemistry.

The Saccharomyces cerevisiae Prp5 Protein Has RNA-dependent ATPase Activity with Specificity for U2 Small Nuclear RNA*

J. Abelson, G. Dalbadie-McFarland, C. O'Day, 1996, The Journal of Biological Chemistry.

Specificity of Prp24 binding to RNA: a role for Prp24 in the dynamic interaction of U4 and U6 snRNAs.

A. Ghetti, J. Abelson, M. Company, 1995, RNA.

A yeast mutant, PRP20, altered in mRNA metabolism and maintenance of the nuclear structure, is defective in a gene homologous to the human gene RCC1 which is involved in the control of chromosome condensation

M. Aebi, M. W. Clark, J. Abelson, 1990, Molecular and General Genetics MGG.

Saccharomyces cerevisiae tRNA ligase. Purification of the protein and isolation of the structural gene.

E. Phizicky, E M Phizicky, R C Schwartz, 1986, The Journal of biological chemistry.

Studies on amber suppressor tRNA.

H. Goodman, S. Brenner, J. Smith, 1966, Cold Spring Harbor symposia on quantitative biology.

Preparation of fluorescent pre-mRNA substrates for an smFRET study of pre-mRNA splicing in yeast.

C. Guthrie, Haralambos Hadjivassiliou, J. Abelson, 2010, Methods in enzymology.

Splicing of tRNA Precursors

S. Westaway, J. Abelson, 1995 .

In vitro trans-splicing in Saccharomyces cerevisiae.

A. Ghetti, J. Abelson, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Bacteriophage T4 tRNAs: structure, genetics, and biosynthesis.

D. Nierlich, J. Abelson, T. Pinkerton, 1975, Brookhaven symposia in biology.

Thiophosphates in yeast U6 snRNA specifically affect pre-mRNA splicing in vitro.

P. Fabrizio, J. Abelson, John R. Abelson, 1992, Nucleic acids research.

Genetic mapping of the inversion loop in bacteriophage Mu DNA.

J. Abelson, E. Daniell, W. Boram, 1973, Proceedings of the National Academy of Sciences of the United States of America.

Nucleotide sequence of an arginine transfer ribonucleic acid from bacteriophage T4.

J. Seidman, W. McClain, G. Mazzara, 1977, The Journal of biological chemistry.

Nicotinic receptor binding site probed with unnatural amino acid incorporation in intact cells.

N. Davidson, S. Silverman, W. Zhong, 1995, Science.

An essential 45 kDa yeast transmembrane protein reacts with anti-nuclear pore antibodies: purification of the protein, immunolocalization and cloning of the gene.

R. Aebersold, R. Rauhut, M. Aebi, 1991, European journal of cell biology.

The generation and analysis of clones containing bacteriophage T4 DNA fragments.

J. Velten, J. Abelson, 1980, Journal of Molecular Biology.

DNA sequence of a T4 transfer RNA gene cluster.

J. Abelson, K. Fukada, 1980, Journal of molecular biology.

Nucleotide sequence determination of bacteriophage T4 leucine transfer ribonucleic acid.

J. Abelson, T. Pinkerton, G. Paddock, 1973, The Journal of biological chemistry.

Deletion analysis of a multifunctional yeast tRNA ligase polypeptide. Identification of essential and dispensable functional domains.

C. Greer, S. Westaway, B. Apostol, 1991, Journal of Biological Chemistry.

Affinity chromatography with biotinylated RNAs.

S. Goelz, Z. Hostomský, S. Ruby, 1990, Methods in enzymology.

An Engineered Tetrahymena tRNAGln for in Vivo Incorporation of Unnatural Amino Acids into Proteins by Nonsense Suppression*

H. Lester, F. Du, J. Sampson, 1996, The Journal of Biological Chemistry.

Construction of two Escherichia coli amber suppressor genes : tRNACUA and tRNACUA ( gene synthesis / amino acid substitution / nonsense suppression

J. Normanly, J. Abelson, JEAN-MICHEL MASSONt, 2022 .

The 2′-5′ RNA Ligase of Escherichia coli

J. Abelson, E. Arn, 1996, The Journal of Biological Chemistry.

Recognition of tRNA(Cys) by Escherichia coli cysteinyl-tRNA synthetase.

G. Komatsoulis, J. Abelson, 1993, Biochemistry.

Yeast tRNA-splicing endonuclease cleaves precursor tRNA in a random pathway.

J. Abelson, F. Miao, 1993, The Journal of biological chemistry.

In vitro synthesis of end-mature, intron-containing transfer RNAs.

V. M. Reyes, J. Abelson, 1989, Methods in enzymology.

Structure and function of the yeast tRNA ligase gene.

E. Phizicky, S. Westaway, J. Abelson, 1988, The Journal of biological chemistry.

Nucleotide sequence of ORF2: an open reading frame upstream of the tRNA ligase gene.

S. Westaway, G. Komatsoulis, J. Abelson, 1987, Nucleic Acids Research.

Purification of yeast transfer RNA ligase.

E. Phizicky, C. Greer, J. Abelson, 1990, Methods in Enzymology.

Genetic regulation: the Lac control region.

W. Reznikoff, J. Abelson, R. C. Dickson, 1975, Science.

Construction of Escherichia coli amber suppressor tRNA genes. II. Synthesis of additional tRNA genes and improvement of suppressor efficiency.

J. Miller, J. Masson, J. Abelson, 1990, Journal of molecular biology.

Crystal structure of a dimeric archaeal splicing endonuclease.

J Abelson, H Li, J. Abelson, 2000, Journal of molecular biology.

Eight base changes are sufficient to convert a leucine-inserting tRNA into a serine-inserting tRNA.

J. Abelson, J. Normanly, T. Ollick, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Cell-Free Circularization of Viroid Progeny RNA by an RNA Ligase from Wheat Germ

H. Robertson, C. Peebles, J. Abelson, 1982, Science.

Sequence organization and control of transcription in the bacteriophage T4 tRNA region.

J. Abelson, J. Abelson, Joel Broida, 1985, Journal of molecular biology.

Enzymatic mechanism of an RNA ligase from wheat germ.

C. Greer, J. Abelson, P. Gegenheimer, 1983, The Journal of biological chemistry.

An RNA ligase from wheat germ which participates in transfer RNA splicing in vitro.

H. Gabius, C. Peebles, J. Abelson, 1983, The Journal of biological chemistry.

Cleavage of T4 species I ribonucleic acid by Escherichia coli ribonuclease III.

H. Robertson, J. Abelson, G. Paddock, 1976, Nucleic acids research.

The nucleotide sequence of threonine transfer RNA coded by bacteriophage T4.

C. Guthrie, J. Abelson, H. Yesian, 1978, Nucleic Acids Research.

Conformational dynamics of single pre-mRNA molecules during in vitro splicing

C. Guthrie, N. Walter, M. Ditzler, 2010, Nature Structural &Molecular Biology.