B. Pardo

发表

βOHB Protective Pathways in Aralar-KO Neurons and Brain: An Alternative to Ketogenic Diet

M. Casarejos, Laura Contreras, J. Satrústegui, 2020, The Journal of Neuroscience.

AGC1‐malate aspartate shuttle activity is critical for dopamine handling in the nigrostriatal pathway

Josep Maria Salanova Grau, M. Dierssen, T. Saheki, 2013, Journal of neurochemistry.

Requirement for Aralar and Its Ca2+-binding Sites in Ca2+ Signal Transduction in Mitochondria from INS-1 Clonal β-Cells*

A. Wiederkehr, C. Wollheim, J. Satrústegui, 2009, Journal of Biological Chemistry.

Acute Effects of 1‐Methyl‐4‐Phenyl‐1, 2, 3, 6‐Tetrahydropyridine in a Model of Rat Designated a Poor Metabolizer of Debrisoquine

F. Jiménez-Jiménez, M. Mena, M. Casarejos, 1991, Journal of neurochemistry.

l‐DOPA Inhibits Complex IV of the Electron Transport Chain in Catecholamine‐Rich Human Neuroblastoma NB69 Cells

M. Mena, J. García de Yébenes, B. Pardo, 1995, Journal of neurochemistry.

Levodopa toxicity in foetal rat midbrain neurones in culture: modulation by ascorbic acid

M. Mena, J. D. de Yébenes, C. Paíno, 1993, Neuroreport.

Neurotoxicity of levodopa on catecholamine‐rich neurons

S. Fahn, M. Mena, M. Casarejos, 1992, Movement disorders : official journal of the Movement Disorder Society.

Changes induced by ovariectomy on the acute effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in a model of rat poor metabolizer of debrisoquine.

F. Jiménez-Jiménez, M. Mena, C. Tabernero, 1996, Parkinsonism & related disorders.

De novo Synthesis of Glial Glutamate and Glutamine in Young Mice Requires Aspartate Provided by the Neuronal Mitochondrial Aspartate-Glutamate Carrier Aralar/AGC1

Laura Contreras, J. Satrústegui, B. Pardo, 2013, Front. Endocrinol..

Effective therapeutic strategies in a preclinical mouse model of Charcot–Marie–Tooth disease

J. Hoenicka, M. Murphy, J. Satrústegui, 2021, Human molecular genetics.

Aggregating Brain Cell Cultures as a Model to Study Ischaemia-induced Neurodegeneration.

P. Honegger, B. Pardo, 1999, Toxicology in vitro : an international journal published in association with BIBRA.

Mitochondrial movement in Aralar/Slc25a12/AGC1 deficient cortical neurons

Laura Contreras, J. Satrústegui, B. Pardo, 2019, Neurochemistry International.

A Ca2+-Dependent Mechanism Boosting Glycolysis and OXPHOS by Activating Aralar-Malate-Aspartate Shuttle, upon Neuronal Stimulation

J. Molgó, J. Satrústegui, E. Rial, 2022, The Journal of Neuroscience.

Emergence of Oriented Cell Assemblies Associated with Spike-Timing-Dependent Plasticity

Marco Tomassini, Jan Eriksson, Alessandro E. P. Villa, 2005, ICANN.

Altered Postnatal Development of Cortico—Hippocampal Neuronal Electric Activity in Mice Deficient for the Mitochondrial Aspartate—Glutamate Transporter

T. Saheki, M. Gómez-Galán, J. Satrústegui, 2012, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Muscimol-induced death of GABAergic neurons in rat brain aggregating cell cultures.

P. Honegger, F. Monnet-Tschudi, B. Pardo, 1998, Brain research. Developmental brain research.

Role of aralar, the mitochondrial transporter of aspartate‐glutamate, in brain N‐acetylaspartate formation and Ca2+ signaling in neuronal mitochondria

T. Saheki, Laura Contreras, J. Satrústegui, 2007, Journal of neuroscience research.

Calcium-Regulation of Mitochondrial Respiration Maintains ATP Homeostasis and Requires ARALAR/AGC1-Malate Aspartate Shuttle in Intact Cortical Neurons

T. Saheki, J. Satrústegui, A. del Arco, 2013, The Journal of Neuroscience.

Essential Role of Aralar in the Transduction of Small Ca+ Signals to Neuronal Mitochondria*

T. Saheki, Keiko Kobayashi, M. Iijima, 2006, Journal of Biological Chemistry.

Mitochondrial transporters as novel targets for intracellular calcium signaling.

Beatriz Pardo, J. Satrústegui, Araceli Del Arco, 2007, Physiological reviews.

Citrin and aralar1 are Ca2+‐stimulated aspartate/glutamate transporters in mitochondria

T. Saheki, M. Runswick, Keiko Kobayashi, 2001, The EMBO journal.

Glutamate excitotoxicity and Ca2+-regulation of respiration: Role of the Ca2+ activated mitochondrial transporters (CaMCs).

Laura Contreras, J. Satrústegui, A. del Arco, 2016, Biochimica et biophysica acta.

AGC1 Deficiency: Pathology and Molecular and Cellular Mechanisms of the Disease

Laura Contreras, J. Satrústegui, A. del Arco, 2022, International journal of molecular sciences.

The regulation of neuronal mitochondrial metabolism by calcium

M. Duchen, G. Szabadkai, J. Satrústegui, 2015, The Journal of physiology.

Differentiation of rat striatal embryonic stem cells in vitro: monolayer culture vs. three‐dimensional coculture with differentiated brain cells

P. Honegger, P Honegger, B Pardo, 2000, Journal of neuroscience research.

l-Lactate-Mediated Neuroprotection against Glutamate-Induced Excitotoxicity Requires ARALAR/AGC1

J. Satrústegui, Irene Pérez-Liébana, I. Llorente-Folch, 2016, The Journal of Neuroscience.

Redox Shuttles in the Brain

Laura Contreras, B. Pardo, 2012 .

“A feed-forward Ca2+-dependent mechanism boosting glycolysis and OXPHOS by activating Aralar-malate-aspartate shuttle, upon neuronal stimulation”

J. Molgó, J. Satrústegui, E. Rial, 2021, bioRxiv.

Brain Glutamine Synthesis Requires Neuronal-Born Aspartate as Amino Donor for Glial Glutamate Formation

Miguel Garzón, Keiko Kobayashi, Beatriz Pardo, 2011, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Reduced N-Acetylaspartate Levels in Mice Lacking Aralar, a Brain- and Muscle-type Mitochondrial Aspartate-glutamate Carrier*

T. Saheki, S. Nakagawa, Keiko Kobayashi, 2005, Journal of Biological Chemistry.

Developmental changes in the Ca2+-regulated mitochondrial aspartate-glutamate carrier aralar1 in brain and prominent expression in the spinal cord.

Keiko Kobayashi, Paola Bovolenta, Alberto Martínez-Serrano, 2003, Brain research. Developmental brain research.

Effects of calcium antagonists on the dopamine system.

M. Mena, M. Casarejos, C. Tabernero, 1995, Clinical neuropharmacology.

Generation of mitochondrial reactive oxygen species is controlled by ATPase inhibitory factor 1 and regulates cognition

Marta P Pereira, R. Artuch, M. Murphy, 2021, PLoS biology.

Calcium regulation of mitochondrial carriers.

Laura Contreras, J. Satrústegui, A. del Arco, 2016, Biochimica et biophysica acta.

The Response to Stimulation in Neurons and Astrocytes

Laura Contreras, J. Satrústegui, Irene Pérez-Liébana, 2019, Neurochemical Research.

Enteric glial cells express full-length TrkB and depend on TrkB expression for normal development

J. Cobo, J. Vega, O. García-Suárez, 2009, Neuroscience Letters.

Regulation of neuronal energy metabolism by calcium: Role of MCU and Aralar/malate-aspartate shuttle.

Laura Contreras, J. Satrústegui, A. del Arco, 2023, Biochimica et biophysica acta. Molecular cell research.

ARALAR/AGC1 deficiency, a neurodevelopmental disorder with severe impairment of neuronal mitochondrial respiration, does not produce a primary increase in brain lactate

M. García-Martín, T. Rodrigues, J. Satrústegui, 2017, Journal of neurochemistry.

Ca(2+) regulation of mitochondrial function in neurons.

Laura Contreras, J. Satrústegui, A. del Arco, 2014, Biochimica et biophysica acta.

Toxic effects of L-DOPA on mesencephalic cell cultures: protection with antioxidants

M. Mena, M. Casarejos, J. D. Yébenes, 1995, Brain Research.

Mitochondrial ATP-Mg/Pi Carrier SCaMC-3/Slc25a23 Counteracts PARP-1-Dependent Fall in Mitochondrial ATP Caused by Excitotoxic Insults in Neurons

J. Esteban, J. Satrústegui, A. del Arco, 2015, The Journal of Neuroscience.

Deficiency of the mitochondrial transporter of aspartate/glutamate aralar/AGC1 causes hypomyelination and neuronal defects unrelated to myelin deficits in mouse brain

T. Saheki, J. Satrústegui, A. del Arco, 2011, Journal of neuroscience research.

Alteration of amino acid metabolism in neuronal aggregate cultures exposed to hypoglycaemic conditions

O. Boulat, H. Henry, O. Braissant, 2002, Journal of neurochemistry.

Ascorbic acid protects against levodopa‐induced neurotoxicity on a catecholamine‐rich human neuroblastoma cell line

S. Fahn, M. Mena, J. D. de Yébenes, 1993, Movement disorders : official journal of the Movement Disorder Society.

High sensitivity of immature GABAergic neurons to blockers of voltage-gated calcium channels.

P. Honegger, B. Pardo, 1999, Brain research. Developmental brain research.

Separate Neuronal and Glial Na+,K+-ATPase Isoforms Regulate Glucose Utilization in Response to Membrane Depolarization and Elevated Extracellular Potassium

P. Honegger, P Honegger, B Pardo, 1999, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Selective neurodegeneration induced in rotation-mediated aggregate cell cultures by a transient switch to stationary culture conditions: a potential model to study ischemia-related pathogenic mechanisms

P. Honegger, B. Pardo, 1999, Brain Research.

Stimulus-Driven Unsupervised Synaptic Pruning in Large Neural Networks

Marco Tomassini, Jan Eriksson, Alessandro E. P. Villa, 2005, BVAI.

Calcium regulation of mitochondrial carriers.

Laura Contreras, J. Satrústegui, A. del Arco, 2016, Biochimica et biophysica acta.

Aggregating brain cell cultures: investigation of stroke related brain damage.

P. Honegger, B. Pardo, 2007, ALTEX.