E. Loža

发表

Synthesis and evaluation of (E)-2-(5-phenylpent-2-en-4-ynamido)cyclohex-1-ene-1-carboxylate derivatives as HCA2 receptor agonists.

R. Petrovska, J. Klovins, G. Duburs, 2017, Bioorganic & medicinal chemistry.

Synthesis and evaluation of (E)-2-(acrylamido)cyclohex-1-enecarboxylic acid derivatives as HCA1, HCA2, and HCA3 receptor agonists.

R. Petrovska, J. Klovins, G. Duburs, 2014, Bioorganic & medicinal chemistry.

Synthesis of 2-substituted oxazoloquinazolinones

O. Bobiļeva, E. Loža, 2018, Chemistry of Heterocyclic Compounds.

Novel sulfonamide derivatives as inhibitors of histone deacetylase

P. Finn, Nagma Khan, N. Law, 2005 .

Suppression of intestinal microbiota-dependent production of pro-atherogenic trimethylamine N-oxide by shifting L-carnitine microbial degradation.

J. Liepiņš, E. Liepinsh, S. Grinberga, 2014, Life sciences.

Inhibition of L‐carnitine biosynthesis and transport by methyl‐γ‐butyrobetaine decreases fatty acid oxidation and protects against myocardial infarction

E. Liepinsh, R. Vilskersts, S. Grinberga, 2015, British journal of pharmacology.

Composes d'acide carbamique comprenant un chainon de piperazine tels que les inhibiteurs hdac

P. Finn, I. Kalvinsh, C. Watkins, 2003 .

Acute and long‐term administration of palmitoylcarnitine induces muscle‐specific insulin resistance in mice

E. Liepinsh, R. Vilskersts, S. Grinberga, 2017, BioFactors.

Binding versus Enzymatic Processing of ε-Trimethyllysine Dioxygenase Substrate Analogues

P. Arsenyan, E. Liepinsh, A. Grandane, 2022, ACS Medicinal Chemistry Letters.

Structure-activity relationship studies on the inhibition of the bacterial translation of novel Odilorhabdins analogues.

V. Ryabova, K. Yadav, D. Hughes, 2020, Bioorganic & medicinal chemistry.

Targeting carnitine biosynthesis: discovery of new inhibitors against γ-butyrobetaine hydroxylase.

A. Kazaks, K. Tārs, E. Liepinsh, 2014, Journal of medicinal chemistry.

Nicotinamide phosphoribosyltransferase inhibitors, design, preparation, and structure-activity relationship.

M. Sehested, S. Nielsen, W. Kiess, 2013, Journal of medicinal chemistry.

Stereochemical aspects of catalytic hydrogenation of 2,3-di- and 2,3,4-tri-substituted 2-cyclopentene-1-ones and reactivity of the resulting cyclopentanones

E. Loža, I. Turovskis, D. Loļa, 1988 .

Aziridine-2-carboxylic acid derivatives and its open-ring isomers as a novel PDIA1 inhibitors

I. Domracheva, E. Loža, V. Andrianov, 2021, Chemistry of Heterocyclic Compounds.

Identification of BBOX1 as a Therapeutic Target in Triple-Negative Breast Cancer.

Laura E. Herring, C. Fan, C. Perou, 2020, Cancer discovery.

Selective inhibition of OCTN2 is more effective than inhibition of gamma-butyrobetaine dioxygenase to decrease the availability of l-carnitine and to reduce myocardial infarct size.

E. Liepinsh, R. Vilskersts, S. Grinberga, 2014, Pharmacological research.

Inhibitors of human histone deacetylase with potent activity against the African trypanosome Trypanosoma brucei

D. Horn, F. Björkling, M. Taylor, 2012, Bioorganic & medicinal chemistry letters.

Synthesis and antitumor effect in vitro and in vivo of substituted 1,3-dihydroindole-2-ones.

M. Sehested, S. Nielsen, P. B. Jensen, 2010, Journal of medicinal chemistry.

The Discovery and Development of Belinostat

P. Finn, E. Loža, E. Carstensen, 2016 .

LC-MS/MS assay for the quantitation of the HDAC inhibitor belinostat and five major metabolites in human plasma.

H. Tawbi, E. Chu, S. Kummar, 2013, Journal of pharmaceutical and biomedical analysis.

Novel amide derivatives as inhibitors of histone deacetylase: design, synthesis and SAR.

Ivars Kalvinsh, Anthony Tumber, Nagma Khan, 2009, European journal of medicinal chemistry.

Enantiomeric enrichment of partially resolved 4-hydroxy-2-carboxymethylcyclopentanone de derivatives by achiral phase chromatography

E. Loža, A. Ķemme, D. Loļa, 1995 .

Synthesis of 2-quinolinecarboxamide derivatives as potential HDAC inhibitors

O. Bobiļeva, E. Loža, O. Habarova, 2011 .

Synthesis of 2‐Quinolinecarboxamide Derivatives as Potential HDAC Inhibitors.

O. Bobiļeva, E. Loža, O. Habarova, 2012 .