Martin C. Cherrier

发表

3-Nitro-4-amino benzoic acids and 6-amino nicotinic acids are highly selective agonists of GPR109b.

D. Connolly, S. Tamura, C. Sage, 2007, Bioorganic & medicinal chemistry letters.

Fluorinated pyrazole acids are agonists of the high affinity niacin receptor GPR109a.

D. Connolly, S. Tamura, Vu P Hong, 2007, Bioorganic & medicinal chemistry letters.

Agonist lead identification for the high affinity niacin receptor GPR109a.

Brian M. Smith, D. Connolly, S. Tamura, 2007, Bioorganic & medicinal chemistry letters.

3-(1H-tetrazol-5-yl)-1,4,5,6-tetrahydro-cyclopentapyrazole (MK-0354): a partial agonist of the nicotinic acid receptor, G-protein coupled receptor 109a, with antilipolytic but no vasodilatory activity in mice.

D. Connolly, S. Tamura, C. Sage, 2008, Journal of medicinal chemistry.

(1aR,5aR)1a,3,5,5a-Tetrahydro-1H-2,3-diaza-cyclopropa[a]pentalene-4-carboxylic acid (MK-1903): a potent GPR109a agonist that lowers free fatty acids in humans.

D. Connolly, J. Knudsen, C. Sage, 2012, Journal of medicinal chemistry.

Potent tricyclic pyrazole tetrazole agonists of the nicotinic acid receptor (GPR109a).

J. Knudsen, C. Sage, E. Carballo-Jane, 2010, Bioorganic & medicinal chemistry letters.

1-Alkyl-benzotriazole-5-carboxylic acids are highly selective agonists of the human orphan G-protein-coupled receptor GPR109b.

D. Connolly, S. Tamura, C. Sage, 2006, Journal of medicinal chemistry.

Identification of fused bicyclic heterocycles as potent and selective 5-HT(2A) receptor antagonists for the treatment of insomnia.

K. Whelan, A. Grottick, Konrad Feichtinger, 2012, Bioorganic & medicinal chemistry letters.

Synthesis and in vivo evaluation of phenethylpiperazine amides: selective 5-hydroxytryptamine(2A) receptor antagonists for the treatment of insomnia.

P. Dosa, K. Whelan, A. Grottick, 2010, Journal of medicinal chemistry.