D. Larsen

发表

R. J. Lins, R. J. Stoodley, D. Larsen, 2001 .

Physicochemical and biological characterization of synthetic phosphatidylinositol dimannosides and analogues.

T. Rades, S. Hook, M. Hubert, 2013, Molecular pharmaceutics.

Soluble CD36 Ectodomain Binds Negatively Charged Diacylglycerol Ligands and Acts as a Co-Receptor for TLR2

R. Dwek, I. Wilson, B. Beutler, 2009, PloS one.

Oligosaccharides related to xyloglucan: Synthesis and X-ray crystal structure of methyl 2-O-(α-l-fucopyranosyl)-β-d-galactopyranoside

J. Simpson, L. Melton, D. Larsen, 1996 .

A synthetic analogue of phosphatidylinositol mannoside is an efficient adjuvant

M. Denis, G. Painter, W. Severn, 2009, Immunopharmacology and immunotoxicology.

Sweet Poisons: Synthetic Strategies towards Tutin Glycosides

Duong Nhu, Bill C. Hawkins, D. Larsen, 2017 .

Probing the Structure-Activity Relationship of the Natural Antifouling Agent Polygodial against both Micro- and Macrofoulers by Semisynthetic Modification.

H. Pavia, C. Hellio, J. Svenson, 2017, Journal of natural products.

A mitochondria-targeted derivative of ascorbate: MitoC

J. Trnka, Robin A. J. Smith, Ellen L. Robb, 2015, Free radical biology & medicine.

Using exomarkers to assess mitochondrial reactive species in vivo.

Edward T Chouchani, H. M. Cochemé, Robin A. J. Smith, 2014, Biochimica et biophysica acta.

Isolation, characterisation, and NMR study of xyloglucan from enzymatically depectinised and non-depectinised apple pomace

L. Melton, D. Larsen, D. Brasch, 1999 .

A mitochondria-targeted mass spectrometry probe to detect glyoxals: implications for diabetes☆

Robin A. J. Smith, A. Logan, Sebastian Rogatti, 2014, Free radical biology & medicine.

Dicopper(II) complexes of a new pyrazolate-containing Schiff-base macrocycle and related acyclic ligand.

S. Brooker, K. Murray, B. Moubaraki, 2007, Dalton transactions.

Oligosaccharides related to xyloglucan: synthesis and X-ray crystal structure of methyl α-l-fucopyranosyl-(1→2)-β-d-galactopyranosyl-(1→2)-α-d-xylopyranoside and the synthesis of methyl α-l-fucopyranosyl-(1→2)-β-d-galactopyranosyl-(1→2)-β-d-xylopyranoside

J. Simpson, L. Melton, D. Larsen, 2000 .

Norborn-2-en-7-ones as physiologically-triggered carbon monoxide-releasing prodrugs† †Electronic supplementary information (ESI) available: Experimental details for the synthesis of compounds, supporting figures and schemes, and NMR spectra. See DOI: 10.1039/c7sc01647f Click here for additional data

M. Brimble, N. J. Stanley, D. Larsen, 2017, Chemical science.

Studies towards Non‐toxic, Water Soluble, Vasoactive Norbornene Organic Carbon Monoxide Releasing Molecules

D. Larsen, I. Sammut, J. C. Harrison, 2020 .

Chemical synthesis and immunosuppressive activity of dipalmitoyl phosphatidylinositol hexamannoside.

W. Martin, J. Harper, B. Compton, 2011, The Journal of organic chemistry.

Alkylations of N(4)-(4-pyridyl)-3,5-di(2-pyridyl)-1,2,4-triazole: first observation of room-temperature rearrangement of an N(4)-substituted triazole to the N(1) analogue.

Jonathan A. Kitchen, S. Brooker, D. Larsen, 2010, Chemistry, an Asian journal.

Physical characterization of synthetic phosphatidylinositol dimannosides and analogues in binary systems with phosphatidylcholine.

T. Rades, S. Hook, M. Hubert, 2014, Molecular pharmaceutics.

Synthesis and Activity of 6″-Deoxy-6″-thio-α-GalCer and Peptide Conjugates.

I. Hermans, B. Compton, G. Painter, 2015, Organic letters.

Phosphatidylinositol mannosides: synthesis and adjuvant properties of phosphatidylinositol di- and tetramannosides.

M. Denis, G. Painter, D. Larsen, 2006, Bioorganic & medicinal chemistry.

A family of 13 tetranuclear zinc(II)-lanthanide(III) complexes of a [3+3] Schiff-base macrocycle derived from 1,4-diformyl-2,3-dihydroxybenzene.

A. Powell, S. Faulkner, S. Brooker, 2011, Dalton transactions.

A PIM₂ analogue suppresses allergic airway disease.

J. Harper, G. Painter, D. Larsen, 2011, Bioorganic & medicinal chemistry.

Synthesis and Toll-like receptor 4 (TLR4) activity of phosphatidylinositol dimannoside analogues.

I. Wilson, W. Martin, J. Harper, 2011, Journal of medicinal chemistry.

Asymmetric Diels–Alder reactions. Part 5. Influence of sugar substituents upon the diastereofacial reactivity of (E-)3-(t-butyldimethylsiloxy)-1-(D-glucopyranosyloxy)buta-1,3-dienes

R. Pritchard, R. J. Stoodley, D. Larsen, 1990 .

Asymmetric Diels–Alder reactions. Part 4. Influence of anomeric configuration and 2′- and 6′-O-benzyl substitution on the diastereofacial reactivity of (E)-3-(t-butyldimethylsiloxy)-1-(2′,3′,4′,6′-tetra-O-acetyl-β-D-glucopyranosyloxy)-buta-1,3-diene

R. J. Stoodley, D. Larsen, 1990 .

Resolution of orthogonally protected myo-inositols with novozym 435 providing an enantioconvergent pathway to Ac2PIM1.

B. Compton, G. Painter, D. Larsen, 2014, The Journal of organic chemistry.

Self-Assembly of Cyclohelicate [M3 L3 ] Triangles Over [M4 L4 ] Squares, Despite Near-Linear Bis-terdentate L and Octahedral M.

A. Garden, S. Brooker, G. Hanan, 2017, Chemistry.

Carbazole-based N4-donor Schiff base macrocycles: obtained metal free and as Cu(ii) and Ni(ii) complexes.

S. Brooker, S. Cameron, D. Larsen, 2017, Dalton transactions.

Acridine-based ligands from cobalt(II) mediated rearrangement of diphenylamine-based starting materials

S. Brooker, D. Larsen, Rajni K. Wilson, 2016 .

Synthesis of orthogonally protected d-olivoside, 1,3-di-O-acetyl-4-O-benzyl-2,6-dideoxy-d-arabinopyranose, as a C-glycosyl donor

J. Simpson, H. Osman, D. Larsen, 2009 .

Phenyl 2,3-O-isopropylidene-1-thio-α-d-rhamnopyranoside

Jim Simpson, Hasnah Osman, Lyall R. Hanton, 2007, Acta crystallographica. Section E, Structure reports online.

5-Bromo-norborn-2-en-7-one derivatives as a carbon monoxide source for palladium catalyzed carbonylation reactions

D. Larsen, China M Payne, Kyu-Il Cho, 2019, RSC advances.

Synthesis and anion binding behaviour of diamide derivatives of pyrrole-2,5-diacetic acid

Philip A. Gale, S. Brooker, D. Larsen, 2004 .

A stereoselective approach to the angucyclinone antibiotics : a total synthesis of the C-1 epimer of (±)-rubiginone B1

D. Larsen, Michael D. Ośhea, 1993 .

Syntheses, structures and tautomers of 2,5-disubstituted pyrroles

S. Brooker, D. Larsen, Rongqing Li, 2003 .

Synthesis of Acyloxy‐Semicyclic Dienes Using an Enyne Metathesis/Ring Closing Metathesis Approach

N. T. Lucas, D. Larsen, Lindon W K Moodie, 2015 .

A Ring‐Closing Enyne Metathesis Approach to Functionalized Semicyclic Dienes: The Total Synthesis of (–)‐Tetrangomycin

D. Larsen, Lindon W K Moodie, 2014 .

Synthetic approaches to the angucycline antibiotics: the total syntheses of (±)-rubiginone B1 and B2, (±)-emycin A, and related analogues

D. Larsen, M. O'shea, 1995 .

Experiments directed towards the synthesis of anthracyclinones. VIII. Functionalization of hydroxyanthraquinones by reductive Claisen rearrangements

R. C. Cambie, D. Larsen, Z. Huang, 1984 .

A stereoselective approach to the angucyclinone antibiotics: A total synthesis of (±)-urdamycinone B

H. Osman, D. Larsen, A. Muralikrishna, 2015 .

Remote stereochemical control in asymmetric Diels–Alder reactions: synthesis of the angucycline antibiotics, (−)-tetrangomycin and MM 47755

J. Simpson, D. Larsen, John S. Landells, 2003 .

Total syntheses of the angucyclinone antibiotics (+)-emycin A and (+)-ochromycinone

S. Brooker, D. Larsen, M. O'shea, 1996 .

An enantioselective synthesis of (+)-bostrycin leading to a revision of the absolute configuration of its natural antipode

R. J. Stoodley, D. Larsen, 1990 .

A hexanuclear iron(III) complex of a hexadentate fully conjugated diimine ligand derived from 1,4-diformyl-2,3-dihydroxybenzene

S. Brooker, H. L. C. Feltham, D. Larsen, 2009 .

A Stereoselective Synthesis of 2,6-Dideoxy-6,6,6-trifluoro-arabino-hexoses via an Asymmetric Diels–Alder Strategy

L. Hanton, D. Larsen, C. Hayman, 1999 .

A Facile Synthesis of 2,6-Dideoxy 6,6,6-Trifluorinated Carbohydrate Analogues

S. Brooker, D. Larsen, C. Hayman, 1998 .

Unusual allylic acetoxylations of silyl enol ethers with lead(IV) acetate

R. J. Stoodley, D. Larsen, F. Tomé, 1993 .

Asymmetric Diels–Alder reactions. Part 3. Influence of butadiene structure upon the diastereofacial reactivity of (E)-1-(2′,3′,4′,6′-tetra-O-acetyl-β-D-glucopyranosyloxy)buta-1,3-dienes

R. J. Stoodley, D. Larsen, 1989 .

Synthesis of water soluble O-glycosides of N-(hydroxyalkyl)aminomethylferrocenes

B. Robinson, J. Simpson, D. Larsen, 2000 .

The dimethoxyphenylbenzyl protecting group: an alternative to the p-methoxybenzyl group for protection of carbohydrates.

G. Painter, D. Larsen, Gregory M. Rankin, 2013, The Journal of organic chemistry.

Synthesis and mass spectral characterization of mycobacterial phosphatidylinositol and its dimannosides.

B. Compton, G. Painter, D. Larsen, 2012, The Journal of organic chemistry.

Synthesis and structure of phosphatidylinositol dimannoside.

M. Denis, G. Painter, D. Larsen, 2007, The Journal of organic chemistry.

Total synthesis of (+)-hatomarubigin B.

S. Brooker, D. Larsen, G. Caygill, 2001, The Journal of organic chemistry.

Cobalt and Silver Complexes of Terdentate Pyrazine‐Based Amide Ligands and Assembly of Monocobalt Building Blocks through a Silver Connector

S. Brooker, D. Larsen, Ryan M. Hellyer, 2009 .

Potential Ambergris Odorants From Abietic Acid

R. Franich, R. C. Cambie, D. Larsen, 1990 .

Role of Phosphatidylinositol Mannosides in the Interaction between Mycobacteria and DC-SIGN

G. Besra, B. Appelmelk, J. Geurtsen, 2009, Infection and Immunity.

Experiments Directed Towards the Synthesis of Anthracyclinones.

C. Rickard, R. C. Cambie, D. Larsen, 1986 .

Experiments Directed Towards the Synthesis of Anthracyclinones. XVI. Tin(IV)- and Titanium(IV)-Mediated Cyclizations of ortho-Allyl-Substituted Homochiral Hydroxyanthraquinone Dioxolans

R. C. Cambie, S. Holroyd, D. Larsen, 1992 .

Diazomethyl ketone substrate derivatives as active-site-directed inhibitors of thiol proteases. Papain.

E. Shaw, H. Watanabe, D. Larsen, 1977, Biochemistry.

Mannosylation of Virus-Like Particles Enhances Internalization by Antigen Presenting Cells

V. Ward, M. Baird, S. Young, 2014, PloS one.

Phosphatidylinositol mannosides: synthesis and suppression of allergic airway disease.

J. Harper, G. Painter, D. Larsen, 2006, Bioorganic & medicinal chemistry.

Soluble human TLR2 ectodomain binds diacylglycerol from microbial lipopeptides and glycolipids

R. Dwek, I. Wilson, M. Wormald, 2015, Innate immunity.

Role of phosphatidylinositol mannosides in the interaction between mycobacteria 1 and DC-SIGN 2 3

B. Appelmelk, J. Geurtsen, N. N. Driessen, 2009 .

Synthetic preparation and immunological evaluation of β-mannosylceramide and related N-acyl analogues.

J. Berzofsky, B. Compton, G. Painter, 2020, Organic & biomolecular chemistry.

Phosphatidylinositol mannoside ether analogues: syntheses and interleukin-12-inducing properties.

M. Denis, G. Painter, Andreas Härer, 2007, The Journal of organic chemistry.

Phosphatidylinositol Mannosides are Efficient Mucosal Adjuvants

M. Denis, G. Painter, A. L. La Flamme, 2008, Immunological investigations.

NKT cell-dependent glycolipid–peptide vaccines with potent anti-tumour activity† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c4sc03599b Click here for additional data file. Click here for additional data file.

M. Brimble, I. Hermans, O. Gasser, 2015, Chemical science.

Major change in regiospecificity for the exo-1,3-β-glucanase from Candida albicans following its conversion to a glycosynthase.

Y. Nakatani, D. Larsen, S. Cutfield, 2014, Biochemistry.

R. J. Lins, R. J. Stoodley, D. Larsen, 2004, Organic & biomolecular chemistry.

The synthesis of pseudo-sugar disaccharides: A diels—alder approach to monocarba-disaccharides

R. J. Stoodley, D. Larsen, Nicholas S. Trotter, 1993 .

A self-adjuvanting vaccine induces cytotoxic T lymphocytes that suppress allergy.

D. Knight, I. Hermans, F. Ronchese, 2014, Nature chemical biology.

Synthetic approaches to the angucycline antibiotics: Synthesis of the C-glycosidic CD ring system

D. Larsen, Fleur L. Andrews, 1994 .

Synthetic Approaches to the Angucycline Antibiotics: A Concise Entry to the Ring System of PD 116740 and TAN 1085

D. Larsen, M. O'shea, 1996 .

Chemical Synthesis of the PAX Protein Inhibitor EG1 and Its Ability to Slow the Growth of Human Colorectal Carcinoma Cells

M. Eccles, J. Ward, C. Stayner, 2021, Frontiers in Oncology.

Adjuvanticity of a Synthetic Phosphatidylinositol Dimannoside to a SubvirionInfluenza Vaccine in an Influenza Mouse Model

A. Heiser, B. Compton, G. Painter, 2015 .

Reductive claisen rearrangements of anthraquinone allyl ethers

H. Gregory McDonald, P. Craw, R. C. Cambie, 1983 .

Synthetic Approaches to the Angucycline Antibiotics. A Route to C-Glycosidic Benz[a]anthraquinones

D. Larsen, L. Larsen, Fleur L. Andrews, 2000 .

Synthetic Approaches to the Angucycline Antibiotics. A Route to C-Glycosidic Benz[a]anthraquinones.

D. Larsen, L. Larsen, Fleur L. Andrews, 2000 .

Functionalisation of Virus-Like Particles Enhances Antitumour Immune Responses

V. Young, V. Ward, M. Baird, 2019, Journal of immunology research.

2-O-β-d-Glucopyranosyl l-Ascorbic Acid, a Stable Form of Vitamin C, Is Widespread in Crop Plants.

T. McGhie, W. Laing, D. Larsen, 2021, Journal of Agricultural and Food Chemistry.

Discovery of a stable vitamin C glycoside in crab apples (Malus sylvestris).

R. Schaffer, R. Espley, T. McGhie, 2020, Phytochemistry.

Quantitative Analysis of Beer Aromatic Alcohols Using Stable Isotope Dilution Assay1

G. Lissens, F. Delvaux, J. Dufour, 2002 .

The kinetics and mechanisms of additions to olefinic substances. Part 16. Addition of halogens to 1,4-benzoquinone and to 1,4-napthoquinone, and dehydrohalogenation of the resulting adducts

D. Larsen, P. Mare, R. C. Atkinson, 1983 .

A convenient intermediate for 4-demethoxyanthracyclinone synthesis

H. Gregory McDonald, R. C. Cambie, D. Larsen, 1983 .

rac-Hatomarubigin C

D. A. McMorran, H. Osman, D. Larsen, 2006 .

A stereoselective approach to the angucyclinone antibiotics: A total synthesis of (±)-rubiginone B1.

D. Larsen, M. O'shea, 1993 .

Synthetic Approaches to the Angucycline Antibiotics: A Synthesis of (±)-Hatomarubigin B and C.

D. Larsen, G. Caygill, Brett S. McFarlane, 1997 .

A Stereoselective Approach to the Angucyclinone Antibiotics: A Total Synthesis of (.+‐.)‐Rubiginone B1.

D. Larsen, M. O'shea, 1993 .

MIS416 as a siRNA Delivery System with the Ability to Target Antigen-Presenting Cells

M. Eccles, G. Webster, S. Young, 2018, Nucleic acid therapeutics.

Regio- and stereo-selective bromoalkoxylations of carbonyl compounds: a route to stereopure α-bromo-α-dioxymethyl carbonyl compounds

R. J. Stoodley, D. Larsen, A. Schofield, 1995 .

Bridging Small Molecules to Modified Bacterial Microparticles Using a Disulphide Linkage: MIS416 as a Cargo Delivery System

M. Eccles, G. Webster, S. Young, 2015, PloS one.