S. Berg

发表

Structural Insights and Biological Effects of Glycogen Synthase Kinase 3-specific Inhibitor AR-A014418*

Sven Hellberg, Stefan Berg, S. Hellberg, 2003, Journal of Biological Chemistry.

Structural Features of Glycosyltransferases Synthesizing Major Bilayer and Nonbilayer-prone Membrane Lipids inAcholeplasma laidlawii and Streptococcus pneumoniae * 210

M. Wikström, M. Edman, Patrik Storm, 2003, The Journal of Biological Chemistry.

Discovery of AZD3839, a potent and selective BACE1 clinical candidate for the treatment of Alzheimer’s Disease*

B. Ploeger, S. Eketjäll, B. Swahn, 2012 .

Evidence for dimeric BACE-mediated APP processing.

U. Lendahl, A. Juréus, K. Kolmodin, 2010, Biochemical and biophysical research communications.

Biotransformation of Two b -Secretase Inhibitors Including Ring Opening and Contraction of a Pyrimidine Ring s

J. Holenz, J. Malmquist, B. Swahn, 2013 .

Identification of amino acids and domains required for catalytic activity of DPPR synthase, a cell wall biosynthetic enzyme of Mycobacterium tuberculosis.

M. Holsters, J. Spencer, M. McNeil, 2008, Microbiology.

Sequence properties of the 1,2-diacylglycerol 3-glucosyltransferase from Acholeplasma laidlawii membranes. Recognition of a large group of lipid glycosyltransferases in eubacteria and archaea.

L. Li, M. Wikström, M. Edman, 2001, The Journal of biological chemistry.

The glycosyltransferases of Mycobacterium tuberculosis - roles in the synthesis of arabinogalactan, lipoarabinomannan, and other glycoconjugates.

P. Brennan, M. Jackson, D. Kaur, 2007, Glycobiology.

Discovery of novel potent and highly selective glycogen synthase kinase-3β (GSK3β) inhibitors for Alzheimer's disease: design, synthesis, and characterization of pyrazines.

Sven Hellberg, Stefan Berg, S. Hellberg, 2012, Journal of medicinal chemistry.

Purification of a phosphatase which hydrolyzes phosphatidic acid, a key intermediate in glucolipid synthesis in Acholeplasma laidlawii A membranes.

S. Berg, A. Wieslander, 1997, Biochimica et biophysica acta.

Biosynthesis of mycobacterial lipoarabinomannan: Role of a branching mannosyltransferase

P. Brennan, B. Gicquel, D. Crick, 2006, Proceedings of the National Academy of Sciences.

Genetic Basis for the Synthesis of the Immunomodulatory Mannose Caps of Lipoarabinomannan in Mycobacterium tuberculosis*

P. Brennan, D. Crick, Premkumar Dinadayala, 2006, Journal of Biological Chemistry.

(R)-(+)-2-[[[3-(Morpholinomethyl)-2H-chromen-8-yl]oxy]methyl] morpholine methanesulfonate: a new selective rat 5-hydroxytryptamine1B receptor antagonist.

L. Larsson, S. Ross, S. Berg, 1998, Journal of medicinal chemistry.

Roles of Conserved Proline and Glycosyltransferase Motifs of EmbC in Biosynthesis of Lipoarabinomannan*

P. Brennan, D. Crick, V. Vissa, 2005, Journal of Biological Chemistry.

GSK-3 Inhibitors for the Treatment of Alzheimer's Disease

R. Bhat, J. Burrows, S. Berg, 2007 .

A zebrafish model of tauopathy allows in vivo imaging of neuronal cell death and drug evaluation.

S. Hellberg, E. Mandelkow, R. Köster, 2009, The Journal of clinical investigation.

Revisiting the peripheral sink hypothesis: inhibiting BACE1 activity in the periphery does not alter β‐amyloid levels in the CNS

U. Lendahl, S. Eketjäll, A. Juréus, 2015, Journal of neurochemistry.

AZD1080, a novel GSK3 inhibitor, rescues synaptic plasticity deficits in rodent brain and exhibits peripheral target engagement in humans

S. Hellberg, R. Bhat, P. Arvidsson, 2013, Journal of neurochemistry.

Biochemical and behavioural effects of isamoltane, a β-adrenoceptor antagonist with affinity for the 5-HT1B receptor of rat brain

L. Larsson, S. Ross, S. Berg, 2004, Naunyn-Schmiedeberg's Archives of Pharmacology.

Population PKPD Modeling of BACE1 Inhibitor-Induced Reduction in Aβ Levels In Vivo and Correlation to In Vitro Potency in Primary Cortical Neurons from Mouse and Guinea Pig

S. Visser, S. Eketjäll, J. Janson, 2014, Pharmaceutical Research.

The Carboxy Terminus of EmbC from Mycobacterium smegmatis Mediates Chain Length Extension of the Arabinan in Lipoarabinomannan*

K. Khoo, J. Spencer, M. McNeil, 2006, Journal of Biological Chemistry.

Aminoimidazoles as BACE-1 inhibitors: the challenge to achieve in vivo brain efficacy.

Britt-Marie Swahn, Margareta Ek, Johan Lindström, 2012, Bioorganic & medicinal chemistry letters.

Functional analysis of a lipid galactosyltransferase synthesizing the major envelope lipid in the Lyme disease spirochete Borrelia burgdorferi.

S. Bergström, S. Berg, P. Comstedt, 2007, FEMS microbiology letters.

Design and synthesis of β-site amyloid precursor protein cleaving enzyme (BACE1) inhibitors with in vivo brain reduction of β-amyloid peptides.

Britt-Marie Swahn, Johan Lindström, Stefan Berg, 2012, Journal of medicinal chemistry.

Synthesis of 3H- and 14C-labeled AR-A000002, a new and selective 5-HT1B/1D ligand

S. Berg, T. Werner, R. Johansson, 2004 .

Combining an amyloid‐beta (Aβ) cleaving enzyme inhibitor with a γ‐secretase modulator results in an additive reduction of Aβ production

R. Cowburn, S. Eketjäll, P. Arvidsson, 2015, The FEBS journal.

Irreversible binding and activity control of the 1,2-diacylglycerol 3-glucosyltransferase from Acholeplasma laidlawii at an anionic lipid bilayer surface.

Patrik Storm, Stefan Berg, Patrik Storm, 2003, Biochemistry.

crystal structure of Glycogen synthase kinase 3 in complexed with inhibitor

S. Hellberg, J. Lucas, J. Ávila, 2004 .

New aminoimidazoles as beta-secretase (BACE-1) inhibitors showing amyloid-beta (A beta ) lowering in brain.

S. Eketjäll, B. Swahn, K. Strömberg, 2012 .