Jinxin Xu

发表

DDX24 Mutations Associated With Malformations of Major Vessels to the Viscera

Y. Liang, Bin Zhou, H. Shan, 2019, Hepatology.

Multiscale characterization reveals oligomerization dependent phase separation of primer-independent RNA polymerase nsp8 from SARS-CoV-2

R. Chen, Yan Bin Dong, Changli Ma, 2021, Communications Biology.

Ligand binding and heterodimerization with retinoid X receptor α (RXRα) induce farnesoid X receptor (FXR) conformational changes affecting coactivator binding

Jinsong Liu, Jinxin Xu, Na Wang, 2018, The Journal of Biological Chemistry.

Biochemical and Structural Insights into the Aminotransferase CrmG in Caerulomycin Biosynthesis.

Weiming Zhu, Yiguang Zhu, Qingbo Zhang, 2016, ACS chemical biology.

SNX16 Regulates the Recycling of E-Cadherin through a Unique Mechanism of Coordinated Membrane and Cargo Binding.

D. Pei, Yongli Shan, Xiaodong Shu, 2017, Structure.

Discovery, optimization and evaluation of 1-(indolin-1-yl)ethan-1-ones as novel selective TRIM24/BRPF1 bromodomain inhibitors.

Yan Zhang, Yong Xu, Qiu-ping Xiang, 2022, European journal of medicinal chemistry.

Structure of Sorting Nexin 11 (SNX11) Reveals a Novel Extended Phox Homology (PX) Domain Critical for Inhibition of SNX10-induced Vacuolation*

Bin Wu, D. Pei, Tingting Xu, 2013, The Journal of Biological Chemistry.

Structural studies reveal flexible roof of active site responsible for ω-transaminase CrmG overcoming by-product inhibition

Ruibo Wu, Weiming Zhu, Yiguang Zhu, 2020, Communications Biology.

Structural studies reveal unique non-canonical regulators of G protein signaling homology (RH) domains in sorting nexins.

R. Chen, Jinsong Liu, Jinxin Xu, 2022, Journal of molecular biology.

Design, synthesis, discovery and SAR of the fused tricyclic derivatives of indoline and imidazolidinone against DENV replication and infection.

Yong-tang Zheng, Rong-Hua Luo, Guo-Chun Zhou, 2022, Bioorganic chemistry.

Residue Asn277 Affects the Stability and Substrate Specificity of the SMG1 Lipase from Malassezia globosa

Pengfei Zhou, Dongming Lan, Yonghua Wang, 2015, International journal of molecular sciences.

Crystal structure of a mono- and diacylglycerol lipase from Malassezia globosa reveals a novel lid conformation and insights into the substrate specificity.

Yonghua Wang, Shulin Hou, Tingting Xu, 2012, Journal of structural biology.

Discovery and Characterization of XY101, a Potent, Selective, and Orally Bioavailable RORγ Inverse Agonist for Treatment of Castration-Resistant Prostate Cancer.

Yan Zhang, Yong Xu, Donghai Wu, 2019, Journal of medicinal chemistry.

Structure of human SNX10 reveals insights into its role in human autosomal recessive osteopetrosis

Qi Wang, D. Pei, Tingting Xu, 2014, Proteins.

Structural insights into the binding mechanism of IDO1 with hydroxylamidine based inhibitor INCB14943.

Tingting Xu, Ke Ding, Jinsong Liu, 2017, Biochemical and biophysical research communications.

Inhibition mechanism and antiviral activity of an α-ketoamide based SARS-CoV-2 main protease inhibitor

X. Xiong, Zi-feng Yang, Tianyu Zhang, 2023, bioRxiv.

Structural studies reveal flexible roof of active site responsible for ω-transaminase CrmG overcoming by-product inhibition

Ruibo Wu, Weiming Zhu, Yiguang Zhu, 2020, Communications Biology.

Ligand binding and heterodimerization with retinoid X receptor alpha (RXR alpha ) induce farnesoid X receptor (FXR) conformational changes affecting co-activator binding.

Jinsong Liu, Jinxin Xu, Na Wang, 2018 .

Molecular Basis for PI(3,5)P2 Recognition by SNX11, a Protein Involved in Lysosomal Degradation and Endosome Homeostasis Regulation.

Bin Wu, Tingting Xu, Xiaodong Shu, 2020, Journal of molecular biology.

Discovery and Characterization of Benzimidazole Derivative XY123 as a Potent, Selective, and Orally Available RORγ Inverse Agonist.

Yan Zhang, Yong Xu, Donghai Wu, 2021, Journal of medicinal chemistry.

Structural basis for functional selectivity and ligand recognition revealed by crystal structures of human secreted phospholipase A2 group IIE

Shulin Hou, Tingting Xu, Ling Chen, 2017, Scientific Reports.

Residue Asn21 acts as a switch for calcium binding to modulate the enzymatic activity of human phospholipase A2 group IIE.

Jun Xie, Shulin Hou, Junping Bai, 2020, Biochimie.

Malassezia globosa MgMDL2 lipase: Crystal structure and rational modification of substrate specificity.

Jinsong Liu, G. Dubin, Dongming Lan, 2017, Biochemical and biophysical research communications.

Structure of the PX domain of SNX25 reveals a novel phospholipid recognition model by dimerization in the PX domain

Tingting Xu, Zhijun Yu, Minhao Wu, 2017, FEBS letters.

Structure of product‐bound SMG1 lipase: active site gating implications

U. Bornscheuer, Dongming Lan, Yonghua Wang, 2015, The FEBS journal.

Crystal structure of human FXR/RXR-LBD heterodimer bound to HNC180 and 9cRA and SRC1

Jinsong Liu, Jinxin Xu, Na Wang, 2018 .

Preclinical evaluation of the SARS-CoV-2 Mpro inhibitor RAY1216 shows improved pharmacokinetics compared with nirmatrelvir

Ji-zheng Chen, Chaofeng Long, Haiming Jiang, 2024, Nature microbiology.