J. Barwell

发表

Structure–activity relationships for α‐calcitonin gene‐related peptide

D. Hay, D. Poyner, D. Rathbone, 2013, British journal of pharmacology.

Structure–activity relationships of the N-terminus of calcitonin gene-related peptide: key roles of alanine-5 and threonine-6 in receptor activation

M. Brimble, D. Hay, D. Poyner, 2013, British journal of pharmacology.

The activation of the CGRP receptor.

C. Reynolds, M. Wheatley, D. Poyner, 2013, Biochemical Society transactions.

RAMPs and CGRP receptors.

D. Hay, J. Simms, D. Poyner, 2012, Advances in experimental medicine and biology.

Non-peptidic antagonists of the CGRP receptor, BIBN4096BS and MK-0974, interact with the calcitonin receptor-like receptor via methionine-42 and RAMP1 via tryptophan-74

M. Wigglesworth, D. Donnelly, D. Poyner, 2010, Biochemical and biophysical research communications.

Receptor activity modifying proteins (RAMPs) interact with the VPAC2 receptor and CRF1 receptors and modulate their function

H. Lindmark, M. Kadmiel, D. Poyner, 2013, British journal of pharmacology.

Lifting the lid on GPCRs: the role of extracellular loops

J. Simms, M. Wheatley, D. Poyner, 2011, British journal of pharmacology.

Production, Purification and Characterization of Recombinant, Full-Length Human Claudin-1

C. Betzel, J. McKeating, N. Bonander, 2013, PloS one.

An allosteric role for receptor activity-modifying proteins in defining GPCR pharmacology

P. Sexton, A. Pioszak, D. Hay, 2016, Cell Discovery.

Structural Basis for Receptor Activity-Modifying Protein-Dependent Selective Peptide Recognition by a G Protein-Coupled Receptor

A. Pioszak, M. Brimble, R. Bill, 2015, Molecular cell.

Receptor activity-modifying protein-dependent effects of mutations in the calcitonin receptor-like receptor: implications for adrenomedullin and calcitonin gene-related peptide pharmacology

R. J. Bailey, D. Hay, D. Poyner, 2014, British journal of pharmacology.

Mapping interaction sites within the N-terminus of the calcitonin gene-related peptide receptor; the role of residues 23–60 of the calcitonin receptor-like receptor

D. Donnelly, D. Poyner, J. Barwell, 2010, Peptides.

Receptor Activity-modifying Proteins 2 and 3 Generate Adrenomedullin Receptor Subtypes with Distinct Molecular Properties

Christopher A. Reynolds, Margaret A. Brimble, Alex C. Conner, 2016, The Journal of Biological Chemistry.

Similarity between class A and class B G-protein-coupled receptors exemplified through calcitonin gene-related peptide receptor modelling and mutagenesis studies

Bruck Taddese, Graham J. G. Upton, Christopher A. Reynolds, 2013, Journal of The Royal Society Interface.

Extracellular loops 1 and 3 and their associated transmembrane regions of the calcitonin receptor-like receptor are needed for CGRP receptor function

D. Poyner, A. Conner, J. Barwell, 2011, Biochimica et biophysica acta.

The role of ECL2 in CGRP receptor activation: a combined modelling and experimental approach

C. Reynolds, D. Hay, D. Poyner, 2013, Journal of The Royal Society Interface.

The role of ECL 2 in CGRP receptor activation : a combined modelling and experimental approach

C. Reynolds, D. Hay, D. Poyner, 2013 .

Calcitonin and calcitonin receptor‐like receptors: common themes with family B GPCRs?

J. Archbold, D. Hay, D. Poyner, 2012, British journal of pharmacology.

Ligand binding and activation of the CGRP receptor.

J. Simms, M. Wheatley, D. Poyner, 2007, Biochemical Society transactions.

The use of site-directed mutagenesis to study GPCRs.

M. Wheatley, D. Poyner, A. Conner, 2011, Methods in molecular biology.

The role of the extracellular loops of the CGRP receptor, a family B GPCR.

M. Wheatley, D. Poyner, James Barwell, 2012, Biochemical Society transactions.

Ligand binding and activation of the CGRP receptor.

J. Simms, M. Wheatley, D. Poyner, 2007, Biochemical Society transactions.

An allosteric role for receptor activity-modifying proteins in defining GPCR pharmacology

P. Sexton, A. Pioszak, D. Hay, 2016, Cell Discovery.

Themed Section: Neuropeptides REVIEW Structure–activity relationships for a-calcitonin gene-related peptide

D. Hay, D. Poyner, D. Rathbone, 2013 .