A. Turner

发表

Structure−Activity Relationship of Hydroxamate-Based Inhibitors on the Secretases that Cleave the Amyloid Precursor Protein, Angiotensin Converting Enzyme, CD23, and Pro-Tumor Necrosis Factor-α†

N. Hooper, R. Mayer, A. Faller, 2002 .

Purification and characterization of smooth muscle cell caveolae

N. Hooper, A. Gilman, J. de Gunzburg, 1994, The Journal of cell biology.

Circulating factors and insulin resistance. I. A novel myoinositol 1,2-cyclic phosphate phosphoglycan insulin antagonist from human plasma is elevated in noninsulin-dependent diabetes mellitus.

N. Hooper, J. Larner, A. Turner, 1995, The Journal of clinical endocrinology and metabolism.

The role of proteolysis in Alzheimer's disease.

N. Hooper, E. Parkin, A. Trew, 2000, Advances in experimental medicine and biology.

Differential effects of glycosphingolipids on the detergent-insolubility of the glycosylphosphatidylinositol-anchored membrane dipeptidase.

N. Hooper, E. Parkin, A. Turner, 2001, The Biochemical journal.

The Amyloid Precursor Protein Is Not Enriched in Caveolae‐Like, Detergent‐Insoluble Membrane Microdomains

N. Hooper, I. Hussain, A. Turner, 1997, Journal of neurochemistry.

Isolation and characterisation of a melon cDNA clone encoding phytoene synthase

D. Grierson, Jane E. Taylor, A. Turner, 1995, Plant Molecular Biology.

Transferrin Fusion Technology: A Novel Approach to Prolonging Biological Half-Life of Insulinotropic Peptides

Jie Zhou, M. Mattson, N. Greig, 2010, Journal of Pharmacology and Experimental Therapeutics.

Inhibition and metal ion activation of pig kidney aminopeptidase P. Dependence on nature of substrate.

N. Hooper, A. Turner, G. S. Lloyd, 1996, Biochemical pharmacology.

Inhibition of α-Secretase by Zinc Metalloproteinase Inhibitors.

N. Hooper, A. Turner, S. Parvathy, 2000, Methods in molecular medicine.

A Point Mutation in the Juxtamembrane Stalk of Human Angiotensin I-converting Enzyme Invokes the Action of a Distinct Secretase*

N. Hooper, E. Sturrock, R. Jacob, 2001, The Journal of Biological Chemistry.

The search for alpha-secretase and its potential as a therapeutic approach to Alzheimer s disease.

N. Hooper, A. Turner, 2002, Current medicinal chemistry.

Comparative study of three PCR assays with antigenaemia and serology for the diagnosis of HCMV infection in thoracic transplant recipients

J. Egan, A. Fox, N. Yonan, 1996, Journal of medical virology.

The Regulation of Carbohydrate Metabolism

A. Turner, D. Turner, 1975 .

Isolation of two differentially glycosylated forms of peptidyl-dipeptidase A (angiotensin converting enzyme) from pig brain: a re-evaluation of their role in neuropeptide metabolism.

N. Hooper, A. Turner, 1987, The Biochemical journal.

The renal membrane dipeptidase (dehydropeptidase I) inhibitor, cilastatin, inhibits the bacterial metallo-beta-lactamase enzyme CphA

N. Hooper, G. Amicosante, S. Keynan, 1995, Antimicrobial agents and chemotherapy.

Catabolism of gastrin releasing peptide and substance P by gastric membrane-bound peptidases

N. Bunnett, M. Orloff, J. Reeve, 1985, Peptides.

Characterization of the glycosyl-phosphatidylinositol-anchored human renal dipeptidase reveals that it is more extensively glycosylated than the pig enzyme.

N. Hooper, J. Keen, A. Turner, 1990, The Biochemical journal.

Lipid modification of proteins : a practical approach

N. Hooper, A. Turner, 1992 .

Membrane protein secretases.

N. Hooper, E. Karran, A. Turner, 1997, The Biochemical journal.

A comparison of the zinc contents and substrate specificities of the endothelial and testicular forms of porcine angiotensin converting enzyme and the preparation of isoenzyme-specific antisera.

N. Hooper, K. Barnes, A. Turner, 1992, The Biochemical journal.

The metabolism of neuropeptides. Neurokinin A (substance K) is a substrate for endopeptidase-24.11 but not for peptidyl dipeptidase A (angiotensin-converting enzyme).

N. Hooper, A. Turner, A. Kenny, 1985, The Biochemical journal.

Isolation of a ripening and wound-induced cDNA from Cucumis melo L. encoding a protein with homology to the ethylene-forming enzyme.

J. Pech, P. Rougé, D. Grierson, 1993, European journal of biochemistry.

A role for calcium and annexins in the formation of caveolae.

N. Hooper, E. Parkin, A. Turner, 1996, Biochemical Society transactions.

Molecular forms of angiotensin-converting enzyme in brain microvessels.

N. Hooper, A. Turner, A. Kenny, 1990, Biochemical Society transactions.

The metabolism of neuropeptides

A. Turner, A. Kenny, R., 2005 .

Cleavage of Alzheimer's amyloid precursor protein by alpha-secretase occurs at the surface of neuronal cells.

N. Hooper, E. Karran, I. Hussain, 1999, Biochemistry.

Alzheimer's amyloid precursor protein alpha-secretase is inhibited by hydroxamic acid-based zinc metalloprotease inhibitors: similarities to the angiotensin converting enzyme secretase.

N. Hooper, E. Karran, I. Hussain, 1998, Biochemistry.

Inhibition by converting enzyme inhibitors of pig kidney aminopeptidase P.

N. Hooper, A. Turner, S. Oppong, 1992, Hypertension.

Cloning, expression, and characterization of human cytosolic aminopeptidase P: a single manganese(II)-dependent enzyme.

N. Hooper, G. Cottrell, A. Turner, 2000, Biochemistry.

Membrane-associated zinc peptidase families: comparing ACE and ACE2

A J Turner, Jodie L. Guy, N. Hooper, 2004, Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics.

Amyloid precursor protein, although partially detergent-insoluble in mouse cerebral cortex, behaves as an atypical lipid raft protein.

N. Hooper, E. Parkin, A. Turner, 1999, The Biochemical journal.

Angiotensin-converting enzyme secretase is inhibited by zinc metalloprotease inhibitors and requires its substrate to be inserted in a lipid bilayer.

N. Hooper, E. Karran, A. Turner, 1997, The Biochemical journal.

The amyloid precursor protein (APP) and the angiotensin converting enzyme (ACE) secretase are inhibited by hydroxamic acid-based inhibitors.

N. Hooper, E. Karran, A. Turner, 1998, Biochemical Society transactions.

Isolation and characterization of two distinct low-density, Triton-insoluble, complexes from porcine lung membranes.

N. Hooper, E. Parkin, A. Turner, 1996, The Biochemical journal.

Identification by site-directed mutagenesis of three essential histidine residues in membrane dipeptidase, a novel mammalian zinc peptidase.

N. Hooper, S. Keynan, A. Turner, 1997, The Biochemical journal.

Site-directed mutagenesis of conserved cysteine residues in porcine membrane dipeptidase. Cys 361 alone is involved in disulfide-linked dimerization.

N. Hooper, S. Keynan, A. Turner, 1996, Biochemistry.

Function and regulation of expression of pulmonary surfactant-associated proteins.

N. Hooper, A. Wittinghofer, J. Whitsett, 1991, The Biochemical journal.

Structural determination of the glycolipid anchors of human and porcine membrane dipeptidases.

M. Ferguson, N. Hooper, I. Brewis, 1993, Biochemical Society transactions.

Targeting proteins to mitochondria: a current overview.

I. Holen, J. Uitto, D. Cooper, 1992, The Biochemical journal.