K. Takeshita

发表

Two reaction sites of a spin label, TEMPOL (4-hydroxy-2,2,6,6-tetramethylpiperidine-N-oxyl), with hydroxyl radical.

T. Ozawa, Keita Saito, K. Takeshita, 2003, Journal of pharmaceutical sciences.

Reaction of para-hydroxybenzoic acid esters with singlet oxygen in the presence of glutathione produces glutathione conjugates of hydroquinone, potent inducers of oxidative stress

Kazuo T. Suzuki, I. Nakanishi, Chiho Nishizawa, 2006, Free radical research.

Irradiation of Phenolic Compounds with Ultraviolet Light Causes Release of Hydrated Electrons

K. Takeshita, Shoko Okazaki, 2018 .

Evaluation of photodynamic activity of C60/2-hydroxypropyl-β-cyclodextrin nanoparticles.

K. Motoyama, F. Hirayama, K. Uekama, 2012, Journal of pharmaceutical sciences.

In vivo monitoring of hydroxyl radical generation caused by x-ray irradiation of rats using the spin trapping/EPR technique.

K. Fujii, K. Anzai, T. Ozawa, 2004, Free radical biology & medicine.

In vivo ESR imaging of redox status in mice after X-ray irradiation, measured by acyl-protected hydroxylamine probe, ACP.

K. Anzai, T. Ozawa, Keita Saito, 2020, Free radical biology & medicine.

Pharmacokinetics of lipophilically different 3-substituted 2,2,5,5-tetramethylpyrrolidine-N-oxyl radicals frequently used as redox probes in in vivo magnetic resonance studies.

K. Takeshita, Shoko Okazaki, Y. Hirose, 2016, Free radical biology & medicine.

Redox evaluation in sepsis model mice by the in vivo ESR technique using acyl-protected hydroxylamine.

K. Takeshita, Y. Tachibana, Shoko Okazaki, 2014, Free radical biology & medicine.

Hydroxyl Radical Generation Caused by the Reaction of Singlet Oxygen with a Spin Trap, DMPO, Increases Significantly in the Presence of Biological Reductants

Kazuo T. Suzuki, Chiho Nishizawa, T. Ozawa, 2004, Free radical research.

Surface-deacetylated chitin nanofibers reinforced with a sulfobutyl ether β-cyclodextrin gel loaded with prednisolone as potential therapy for inflammatory bowel disease.

S. Ifuku, F. Hirayama, K. Uekama, 2017, Carbohydrate polymers.

An evaluation of novel biological activity in a crude extract from Hemerocallis fulva L. var. sempervirens M. Hotta

M. Otagiri, H. Moriuchi, K. Yamasaki, 2014, Natural product research.

Differences in pharmacokinetic behaviors of two lipophilic 3‐substituted 2,2,5,5‐tetramethylpyrrolidine‐N‐oxyl radicals, in vivo probes to assess the redox status in the brain using magnetic resonance techniques

M. Tsukamoto, K. Takeshita, Shoko Okazaki, 2020, Magnetic resonance in medicine.

Application of a Compact Magnetic Resonance Imaging System with 1.5 T Permanent Magnets to Visualize Release from and the Disintegration of Capsule Formulations in Vitro and in Vivo.

K. Takeshita, Shoko Okazaki, Kyosuke Shinada, 2017, Biological & pharmaceutical bulletin.

Comparison of stable nitroxide, 3-substituted 2,2,5,5-tetramethylpyrrolidine-N-oxyls, with respect to protection from radiation, prevention of DNA damage, and distribution in mice.

I. Nakanishi, T. Moritake, K. Anzai, 2006, Free radical biology & medicine.

Kinetic study on ESR signal decay of nitroxyl radicals, potent redox probes for in vivo ESR spectroscopy, caused by reactive oxygen species.

K. Anzai, T. Ozawa, Keita Saito, 2002, Biochimica et biophysica acta.

In vivo ESR measurements of free radical reactions in living mice.

H. Utsumi, K. Takeshita, K. Ichikawa, 1995, Toxicology letters.

In vivo ESR measurements of free radical reactions in living mice.

Y. Chung, H. Utsumi, K. Takeshita, 1995, The Journal of toxicological sciences.

Enzymatic reduction-resistant nitroxyl spin probes with spirocyclohexyl rings

K. Sawai, T. Masumizu, K. Takeshita, 2007, Free radical research.

Recent progress in in vivo ESR spectroscopy.

T. Ozawa, K. Takeshita, 2004, Journal of radiation research.

Whole mouse measurement of paramagnetism-loss of nitroxide free radical in lung with a L-band ESR spectrometer.

H. Utsumi, A. Hamada, K. Takeshita, 1993, Biochemistry and molecular biology international.

H. Utsumi, A. Hamada, K. Takeshita, 1999, Free radical biology & medicine.

Hydroxyl radical generation via photoreduction of a simple pyridine N-oxide by an NADH analogue.

K. Ohkubo, S. Fukuzumi, S. Hecht, 2005, Organic & biomolecular chemistry.

Effect of cholesterol on distribution of stable, hydrophobic perchlorotriphenylmethyl triethylester radical incorporated in lecithin liposomal membranes.

K. Takeshita, Shoko Okazaki, Hisao Kansui, 2011, Chemical & pharmaceutical bulletin.

In vivo oxygen radical generation in the skin of the protoporphyria model mouse with visible light exposure: an L-band ESR study.

H. Utsumi, H. Hirata, M. Ono, 2004, The Journal of investigative dermatology.

Relaxation rates for spirocyclohexyl nitroxyl radicals are suitable for interspin distance measurements at temperatures up to about 125 K.

S. Eaton, G. Eaton, M. Mannan, 2009, Chemical communications.

In vivo generation of free radicals in the skin of live mice under ultraviolet light, measured by L-band EPR spectroscopy.

H. Hirata, M. Ono, T. Ozawa, 2006, Free radical biology & medicine.

Singlet Oxygen–mediated Hydroxyl Radical Production in the Presence of Phenols: Whether DMPO–·OH Formation Really Indicates Production of ·OH?¶

T. Ozawa, M. Kawaguchi, K. Takeshita, 2003 .

Singlet Oxygen–mediated Hydroxyl Radical Production in the Presence of Phenols: Whether DMPO–·OH Formation Really Indicates Production of ·OH? ¶

T. Ozawa, M. Kawaguchi, K. Takeshita, 2003, Photochemistry and photobiology.

Characterization of Transgenic Tobacco with an Increased α-Linolenic Acid Level

H. Utsumi, K. Iba, H. Kodama, 1998 .

Assessment of ESR-CT imaging by comparison with autoradiography for the distribution of a blood-brain-barrier permeable spin probe, MC-PROXYL, to rodent brain.

Sentaro Takahashi, Masaichi-chang-il Lee, T. Masumizu, 2003, Magnetic resonance imaging.

ESR measurement of radical clearance in lung of whole mouse.

H. Utsumi, A. Hamada, K. Takeshita, 1991, Biochemical and biophysical research communications.

The preparation and validation of chitosan tablets that rapidly disperse and disintegrate as an oral adsorbent in the treatment of lifestyle-related diseases.

F. Hirayama, M. Otagiri, M. Anraku, 2021, Carbohydrate polymers.

Pharmacokinetic study of acyl-protected hydroxylamine probe, 1-acetoxy-3-carbamoyl-2,2,5,5-tetramethylpyrrolidine, for in vivo measurements of reactive oxygen species.

K. Anzai, T. Ozawa, Keita Saito, 2004, Free radical biology & medicine.

Heterogeneity of regional redox status and relation of the redox status to oxygenation in a tumor model, evaluated using electron paramagnetic resonance imaging.

P. Kuppusamy, M. Krishna, M. Ono, 2010, Cancer research.

Protective effects of 2-aminoethylthiosulfuric acid and structurally analogous organosulfur compounds against ionizing radiation

T. Ozawa, K. Takeshita, M. Ueno, 2023, Journal of clinical biochemistry and nutrition.

In vivo EPR measurement of radical reaction in whole mice--influence of inspired oxygen and ischemia-reperfusion injury on nitroxide reduction.

H. Utsumi, A. Hamada, H Utsumi, 1993, Free radical research communications.

Noninvasive detection of hydroxyl radical generation in lung by diesel exhaust particles.

H. Utsumi, K. Takeshita, J. Y. Han, 2001, Free radical biology & medicine.

Dynamic properties of the haptenic site of lipid haptens in phosphatidylcholine membranes. Their relation to the phase transition of the host lattice.

H. Utsumi, A. Hamada, K. Takeshita, 1987, Biophysical journal.

Polymeric micelles of zinc protoporphyrin for tumor targeted delivery based on EPR effect and singlet oxygen generation

H. Maeda, K. Greish, A. Iyer, 2007, Journal of drug targeting.

Scandium ion-accelerated scavenging reaction of cumylperoxyl radical by a cyclic nitroxyl radical via electron transfer

K. Ohkubo, S. Fukuzumi, H. Kanazawa, 2007 .

Singlet oxygen-dependent hydroxyl radical formation during uroporphyrin-mediated photosensitization in the presence of NADPH.

T. Ozawa, K. Takeshita, M. Mizuno, 2000, Antioxidants & redox signaling.

Small-volume extrusion apparatus for preparation of large, unilamellar vesicles.

R. Macdonald, R. Macdonald, B. Menco, 1991, Biochimica et biophysica acta.

Nitroxyl radicals remarkably enhanced the superoxide anion radical-induced chemiluminescence of Cypridina luciferin analogues.

K. Takeshita, Shoko Okazaki, Akiko Itoda, 2013, Analytical chemistry.

Recent progress in in vivo ESR spectroscopy.

T. Ozawa, K. Takeshita, 2004, Journal of radiation research.

Radical reactions induced by ketoprofen in phospholipid membranes under ultraviolet light irradiation.

K. Takeshita, Shoko Okazaki, A. Hirata, 2020, Journal of photochemistry and photobiology. B, Biology.