Young Sun Lee

Loss of CHD1 Promotes Heterogeneous Mechanisms of Resistance to AR-Targeted Therapy via Chromatin Dysregulation

C. Mason, S. Lowe, Xiaoling Li, 2020, Cancer cell.

GREB1 amplifies androgen receptor output in human prostate cancer and contributes to antiandrogen resistance

D. Zheng, A. Gopalan, C. Sawyers, 2019, eLife.

Defining the therapeutic selective dependencies for distinct subtypes of PI3K pathway-altered prostate cancers

N. Rosen, A. Hsieh, B. Carver, 2021, Nature Communications.

Tumor Microenvironment-Derived NRG1 Promotes Antiandrogen Resistance in Prostate Cancer

Vianne R. Gao, K. Manova-Todorova, A. Gopalan, 2020, Cancer cell.

Rapid interrogation of cancer cell of origin through CRISPR editing

B. Carver, C. Sawyers, E. de Stanchina, 2021, Proceedings of the National Academy of Sciences.

Aberrant Expression of ERG Promotes Resistance to Combined PI3K and AR Pathway Inhibition through Maintenance of AR Target Genes

H. Hieronymus, A. Gopalan, B. Carver, 2019, Molecular Cancer Therapeutics.

Oncogenic ERG Represses PI3K Signaling through Downregulation of IRS2

H. Hieronymus, N. Rosen, A. Gopalan, 2020, Cancer Research.

ERG-driven prostate cancer emerges from basal-luminal hybrid cells

C. Leslie, E. Stanchina, A. Gopalan, 2023 .