A. Thornhill

Tumour kinome re-wiring governs resistance to palbociclib in oestrogen receptor positive breast cancers, highlighting new therapeutic modalities

M. Dowsett, S. Johnston, A. Ressa, 2020, Oncogene.

EGFR/HER2 inhibitor AEE788 increases ER-mediated transcription in HER2/ER-positive breast cancer cells but functions synergistically with endocrine therapy

M. Dowsett, S. Pancholi, D. Evans, 2010, British Journal of Cancer.

Divergent effects of ornithine decarboxylase inhibition on murine erythropoietic precursor cell proliferation and differentiation.

P. McCann, E. Niskanen, A. Thornhill, 1983, Cancer research.

Targeting tumour re-wiring by triple blockade of mTORC1, epidermal growth factor, and oestrogen receptor signalling pathways in endocrine-resistant breast cancer

M. Dowsett, S. Johnston, E. Schuster, 2018, Breast Cancer Research.

Effectiveness and molecular interactions of the clinically active mTORC1 inhibitor everolimus in combination with tamoxifen or letrozole in vitro and in vivo

M. Dowsett, H. Lane, S. Johnston, 2012, Breast Cancer Research.

Discovery of naturally occurring ESR1 mutations in breast cancer cell lines modelling endocrine resistance

Steffi Oesterreich, Simak Ali, Jason Carroll, 2017, Nature Communications.

Discovery of naturally occurring ESR1 mutations in breast cancer cell lines modelling endocrine resistance

M. Dowsett, Simak Ali, J. Carroll, 2017, Nature Communications.

Targeting tumour re-wiring by triple blockade of mTORC1, epidermal growth factor, and oestrogen receptor signalling pathways in endocrine-resistant breast cancer

M. Dowsett, S. Johnston, E. Schuster, 2018, Breast Cancer Research.