A. Ferenbach

发表

Targeting a critical step in fungal hexosamine biosynthesis

D. V. van Aalten, D. Robinson, O. Raimi, 2020, The Journal of Biological Chemistry.

Genetic validation of Aspergillus fumigatus phosphoglucomutase as a viable therapeutic target in invasive aspergillosis

D. V. van Aalten, O. Raimi, W. Fang, 2022, The Journal of biological chemistry.

Catalytic deficiency of O-GlcNAc transferase leads to X-linked intellectual disability

D. V. van Aalten, M. Gundogdu, S. Joss, 2019, Proceedings of the National Academy of Sciences.

CRISPR-Cas9-mediated depletion of O-GlcNAc hydrolase and transferase for functional dissection of O-GlcNAcylation in human cells

A. Ferenbach, A. Gorelik, 2020, bioRxiv.

O-GlcNAcase contributes to cognitive function in Drosophila

D. V. van Aalten, A. Schenck, Michaela Fenckova, 2020, The Journal of Biological Chemistry.

Mechanisms of redundancy and specificity of the Aspergillus fumigatus Crh transglycosylases

Bin Wang, D. V. van Aalten, A. Sanz, 2019, Nature Communications.

A mutant O-GlcNAcase enriches Drosophila developmental regulators.

D. V. van Aalten, D. Campbell, R. Gourlay, 2017, Nature chemical biology.

A missense mutation in the catalytic domain of O‐GlcNAc transferase links perturbations in protein O‐GlcNAcylation to X‐linked intellectual disability

S. Pajusalu, K. Õunap, M. Gundogdu, 2019, FEBS letters.

University of Dundee A missense mutation in the catalytic domain of O-GlcNAc transferase links perturbations in protein O-GlcNAcylation to X-linked intellectual disability Pravata,

S. Pajusalu, K. Õunap, M. Gundogdu, 2019 .

Nucleocytoplasmic human O-GlcNAc transferase is sufficient for O-GlcNAcylation of mitochondrial proteins

A. Ferenbach, Riccardo Trapannone, D. Mariappa, 2016, The Biochemical journal.

Functional domains of the Xenopus replication licensing factor Cdt1

J. Blow, Anatoliy Li, M. Brito-Martins, 2005, Nucleic acids research.

Intellectual disability-associated disruption of O-GlcNAc cycling impairs habituation learning in Drosophila

D. V. van Aalten, A. Schenck, Michaela Fenckova, 2022, PLoS genetics.

The Early Metazoan Trichoplax adhaerens Possesses a Functional O-GlcNAc System

Henk W. P. van den Toorn, A. Heck, D. V. van Aalten, 2015, The Journal of Biological Chemistry.

Microsoft Word-taog_v9_all.docx

Henk W. P. van den Toorn, A. Heck, D. V. van Aalten, 2015 .

GacA is essential for Group A S treptococcus and defines a new class of monomeric dTDP‐4‐dehydrorhamnose reductases (RmlD)

Samantha L. van der Beek, D. V. van Aalten, Y. Le Breton, 2015, Molecular microbiology.

O-GlcNAcylation enhances CPS1 catalytic efficiency for ammonia and promotes ureagenesis

N. Brunetti‐Pierri, D. V. van Aalten, E. Richard, 2022, Nature Communications.

The citron homology domain as a scaffold for Rho1 signaling

D. V. van Aalten, Wenfan Wei, S. G. Bartual, 2021, Proceedings of the National Academy of Sciences.

Genetic and structural validation of phosphomannomutase as a cell wall target in Aspergillus fumigatus

D. V. van Aalten, Ling Lu, O. Raimi, 2021, Molecular microbiology.

Catalytic deficiency of O-GlcNAc transferase leads to X-linked intellectual disability

D. V. van Aalten, M. Gundogdu, S. Joss, 2019, Proceedings of the National Academy of Sciences.

Intellectual disability-associated disruption of O-GlcNAcylation impairs neuronal development and cognitive function in Drosophila

D. V. van Aalten, A. Schenck, Michaela Fenckova, 2022, bioRxiv.

Mutations in N-acetylglucosamine (O-GlcNAc) transferase in patients with X-linked intellectual disability

R. Pfundt, D. V. van Aalten, M. Kempers, 2017, The Journal of Biological Chemistry.

A missense mutation in a patient with developmental delay affects the activity and structure of the hexosamine biosynthetic pathway enzyme AGX1

D. V. van Aalten, O. Raimi, A. Ferenbach, 2020, FEBS letters.

Structure of a bacterial putative acetyltransferase defines the fold of the human O-GlcNAcase C-terminal domain

A. W. Schüttelkopf, D. V. van Aalten, I. Navratilova, 2013, Open Biology.

Genetic recoding to dissect the roles of site-specific protein O-GlcNAcylation

D. V. van Aalten, S. G. Bartual, V. Borodkin, 2019, Nature Structural & Molecular Biology.

University of Dundee Mechanisms of redundancy and specificity of the Aspergillus fumigatus Crh

A. Sanz, J. Arroyo, S. G. Bartual, 2019 .

Evidence for a Functional O-Linked N-Acetylglucosamine (O-GlcNAc) System in the Thermophilic Bacterium Thermobaculum terrenum

D. V. van Aalten, A. Lebedev, M. Gundogdu, 2015, The Journal of Biological Chemistry.

Dual functionality of O-GlcNAc transferase is required for Drosophila development

D. V. van Aalten, H. Müller, O. Raimi, 2015, Open Biology.

O-GlcNAc transferase invokes nucleotide sugar pyrophosphate participation in catalysis

A. W. Schüttelkopf, D. V. van Aalten, D. Robinson, 2012, Nature chemical biology.

A mechanism-inspired UDP-N-acetylglucosamine pyrophosphorylase inhibitor

Michael D. Urbaniak, M. Ferguson, D. V. van Aalten, 2020, RSC chemical biology.

An O-GlcNAc transferase pathogenic variant that affects pluripotent stem cell self-renewal

D. V. van Aalten, A. Bayat, M. Stavridis, 2023, bioRxiv.

Effects of hypo-O-GlcNAcylation on Drosophila development

D. V. van Aalten, A. Ferenbach, D. Mariappa, 2018, The Journal of Biological Chemistry.

A mutant O-GlcNAcase as a probe to reveal global dynamics of protein O-GlcNAcylation during Drosophila embryonic development.

I. Navratilova, J. Alonso, V. Borodkin, 2015, The Biochemical journal.

Recognition of a glycosylation substrate by the O-GlcNAc transferase TPR repeats

D. V. van Aalten, V. Borodkin, O. Raimi, 2017, Open Biology.

O-GlcNAcase Fragment Discovery with Fluorescence Polarimetry.

D. V. van Aalten, I. Navratilova, V. Borodkin, 2018, ACS chemical biology.

A Structural and Biochemical Model of Processive Chitin Synthesis

D. V. van Aalten, V. Borodkin, A. Ferenbach, 2014, The Journal of Biological Chemistry.

Mechanisms of redundancy and specificity of the Aspergillus fumigatus Crh transglycosylases

Bin Wang, D. V. van Aalten, A. Sanz, 2019, Nature Communications.

An O-GlcNAc transferase pathogenic variant that 1 affects pluripotent stem cell self-renewal 2 3

A. Bayat, M. Stavridis, C. Fenger, 2023 .

An O-GlcNAc transferase pathogenic variant linked to intellectual disability affects pluripotent stem cell self-renewal

D. V. van Aalten, A. Bayat, M. Stavridis, 2023, Disease models & mechanisms.

Rescuable sleep and synaptogenesis phenotypes in a Drosophila model of O-GlcNAc transferase intellectual disability

D. V. van Aalten, A. Ferenbach, Laurin McDowall, 2023, bioRxiv.

Neurodevelopmental defects in a mouse model of O-GlcNAc transferase intellectual disability

D. V. van Aalten, A. McNeilly, N. Ondrušková, 2023, bioRxiv.

Processive Chitin Synthesis A Structural and Biochemical Model of

E. Matrices, A. Ferenbach, H. Dorfmueller, 2014 .

A mutant O-GlcNAcase enriches Drosophila developmental regulators.

D. V. van Aalten, D. Campbell, M. Trost, 2017, Nature chemical biology.

Exploiting O-GlcNAc transferase promiscuity to dissect site-specific O-GlcNAcylation

D. V. van Aalten, S. G. Bartual, A. Ferenbach, 2023, bioRxiv.

O-GlcNAcylation of the intellectual disability protein DDX3X exerts proteostatic cell cycle control

D. V. van Aalten, A. Ferenbach, Florence Authier, 2024, bioRxiv.

Neuroectoderm phenotypes in a human stem cell model of O-GlcNAc transferase associated with intellectual disability.

D. V. van Aalten, A. Ferenbach, Marta Murray, 2024, Molecular genetics and metabolism.

Neuroectoderm phenotypes in a human stem cell model of O-GlcNAc transferase intellectual disability

D. V. van Aalten, A. Ferenbach, Marta Murray, 2023, bioRxiv.