Audrius Zakšauskas

发表

Thermodynamic, kinetic, and structural parameterization of human carbonic anhydrase interactions toward enhanced inhibitor design

J. Ladbury, S. Gražulis, Lina Baranauskienė, 2018, Quarterly Reviews of Biophysics.

Methyl 2-Halo-4-Substituted-5-Sulfamoyl-Benzoates as High Affinity and Selective Inhibitors of Carbonic Anhydrase IX

A. Kazaks, K. Tārs, S. Gražulis, 2021, International journal of molecular sciences.

Switching the Inhibitor‐Enzyme Recognition Profile via Chimeric Carbonic Anhydrase XII

Wen-Yih Chen, J. Ladbury, S. Gražulis, 2021, ChemistryOpen.

Benzimidazole design, synthesis, and docking to build selective carbonic anhydrase VA inhibitors.

V. Kairys, D. Matulis, E. Čapkauskaitė, 2017, Bioorganic & medicinal chemistry.

Functionalization of Fluorinated Benzenesulfonamides and Their Inhibitory Properties toward Carbonic Anhydrases

S. Gražulis, D. Matulis, A. Smirnov, 2015, ChemMedChem.

Halogenated and di-substituted benzenesulfonamides as selective inhibitors of carbonic anhydrase isoforms.

A. Kazaks, K. Tārs, S. Gražulis, 2019, European journal of medicinal chemistry.

Design of two-tail compounds with rotationally fixed benzenesulfonamide ring as inhibitors of carbonic anhydrases.

S. Gražulis, D. Matulis, A. Smirnov, 2018, European journal of medicinal chemistry.

Intrinsic Thermodynamics and Structures of 2,4‐ and 3,4‐Substituted Fluorinated Benzenesulfonamides Binding to Carbonic Anhydrases

S. Gražulis, J. Matulienė, D. Matulis, 2017, ChemMedChem.

Picomolar fluorescent probes for compound affinity determination to carbonic anhydrase IX expressed in live cancer cells

L. Dubois, Lina Baranauskienė, J. Matulienė, 2022, Scientific Reports.

Purification, enzymatic activity and inhibitor discovery for recombinant human carbonic anhydrase XIV.

Lina Baranauskienė, D. Matulis, Audrius Zakšauskas, 2016, Journal of biotechnology.

Discovery and characterization of novel selective inhibitors of carbonic anhydrase IX.

J. Ladbury, S. Gražulis, Lina Baranauskienė, 2014, Journal of medicinal chemistry.

PLBD: protein–ligand binding database of thermodynamic and kinetic intrinsic parameters

H. Schiöth, J. Ladbury, S. Gražulis, 2023, Database J. Biol. Databases Curation.