P. McDonnell

发表

Assessing compound binding to the Eg5 motor domain using a thermal shift assay.

M. Doyle, V. Goldfarb, W. Metzler, 2009, Analytical biochemistry.

NMR structure of a potent small molecule inhibitor bound to human keratinocyte fatty acid-binding protein.

Stephen R. Johnson, David S. Taylor, K. Constantine, 2006, Journal of medicinal chemistry.

Using capillary electrophoresis/frontal analysis to screen drugs interacting with human serum proteins

G. Caldwell, J. Masucci, P. McDonnell, 1998, Electrophoresis.

Synthesis and SAR of pyrrolotriazine-4-one based Eg5 inhibitors.

L. Mueller, S. Sheriff, David K. Williams, 2006, Bioorganic & medicinal chemistry letters.

NEMO binding domain of IKK‐2 encompasses amino acids 735–745

C. Mapelli, D. Riexinger, R. Ryseck, 2006, Journal of molecular recognition : JMR.

Using affinity capillary electrophoresis to study the interaction of the extracellular binding domain of erythropoietin receptor with peptides.

L. Jolliffe, D. Johnson, G. Caldwell, 1999, Journal of biochemical and biophysical methods.

Cloning, purification, crystallization and preliminary X-ray analysis of the catalytic domain of human receptor-like protein tyrosine phosphatase γ in three different crystal forms.

V. Goldfarb, W. Metzler, K. Kish, 2011, Acta crystallographica. Section F, Structural biology and crystallization communications.

Conformationally constrained ortho-anilino diaryl ureas: discovery of 1-(2-(1'-neopentylspiro[indoline-3,4'-piperidine]-1-yl)phenyl)-3-(4-(trifluoromethoxy)phenyl)urea, a potent, selective, and bioavailable P2Y1 antagonist.

Steven A. Spronk, P. Lam, D. Schnur, 2013, Journal of medicinal chemistry.

A New Substrate for the Biginelli Cyclocondensation: Direct Preparation of 5-Unsubstituted 3,4-Dihydropyrimidin-2(1H)-ones from a β-Keto Carboxylic Acid

P. McDonnell, J. Bussolari, Patricia A. McDonnell, 2000 .

Structure-based design of potent and selective inhibitors of collagenase-3 (MMP-13).

W. Metzler, Soong-Hoon Kim, Kenneth J. Leavitt, 2005, Bioorganic & medicinal chemistry letters.

Stereoselectivity in the rhodium(II) acetate catalysed cyclopropanations of 2-diazo-1-indanone with styrenes

William Bauta, G. Leo, J. Dodd, 2000 .

Experimental nuclear magnetic resonance studies of membrane proteins.

S. Opella, P. McDonnell, Y. Kim, 1994, Methods in enzymology.

Inhibitors of human mitotic kinesin Eg5: characterization of the 4-phenyl-tetrahydroisoquinoline lead series.

Wayne Vaccaro, Steven Sheriff, Neil Burford, 2006, Bioorganic & medicinal chemistry letters.

Inhibition of influenza virus replication via small molecules that induce the formation of higher-order nucleoprotein oligomers

Eric T Baldwin, Samuel W Gerritz, Michael Sinz, 2011, Proceedings of the National Academy of Sciences.

Multiple and single binding modes of fragment-like kinase inhibitors revealed by molecular modeling, residue type-selective protonation, and nuclear overhauser effects.

Wayne Vaccaro, Luciano Mueller, K. Constantine, 2008, Journal of medicinal chemistry.

Small molecule receptor protein tyrosine phosphatase γ (RPTPγ) ligands that inhibit phosphatase activity via perturbation of the tryptophan-proline-aspartate (WPD) loop.

V. Goldfarb, B. Beno, J. Macor, 2011, Journal of medicinal chemistry.

fd coat protein structure in membrane environments.

S. Opella, K. Shon, P. McDonnell, 1993, Journal of molecular biology.

Effect of detergent concentration on multidimensional solution NMR spectra of membrane proteins in micelles

S. Opella, P. McDonnell, 1993 .

Addition of Acrylamide to Amino Aldehydes to Generate Non-Baylis-Hillman Adducts. Formation of Novel N-Acylhemiaminals

W. Murray, K. Beers, P. McDonnell, 1998 .

NMR THREE-DIMENSIONAL SOLUTION STRUCTURE OF THE SERINE PROTEASE INHIBITOR CYCLOTHEONAMIDE A

B. Podlogar, G. Leo, G. Caldwell, 1997 .