B. Nowicka-Sans

发表

Mechanistic Studies and Modeling Reveal the Origin of Differential Inhibition of Gag Polymorphic Viruses by HIV-1 Maturation Inhibitors

N. Meanwell, Hong Yang, Zeyu Lin, 2016, PLoS pathogens.

Maturation Inhibitor with Improved Potency, Anti-viral Spectrum and Gag Polymorphic

N. Meanwell, Zeyu Lin, M. Krystal, 2016 .

Identification and Characterization of BMS-955176, a Second-Generation HIV-1 Maturation Inhibitor with Improved Potency, Antiviral Spectrum, and Gag Polymorphic Coverage

N. Meanwell, Zeyu Lin, M. Krystal, 2016, Antimicrobial Agents and Chemotherapy.

Increased sensitivity of HIV variants selected by attachment inhibitors to broadly neutralizing antibodies.

L. Alexander, M. Krystal, R. Colonno, 2010, Virology.

Envelope Conformational Changes Induced by Human Immunodeficiency Virus Type 1 Attachment Inhibitors Prevent CD4 Binding and Downstream Entry Events

James E. Robinson, R. Colonno, P. Clapham, 2006, Journal of Virology.

Discovery of BMS-955176, a Second Generation HIV-1 Maturation Inhibitor with Broad Spectrum Antiviral Activity.

B. Beno, N. Meanwell, Zeyu Lin, 2016, ACS medicinal chemistry letters.

Entecavir Exhibits Inhibitory Activity against Human Immunodeficiency Virus under Conditions of Reduced Viral Challenge

N. Parkin, M. Krystal, R. Colonno, 2008, Antimicrobial Agents and Chemotherapy.

Entecavir Exhibits Inhibitory Activity against Human Immunodeﬁciency Virus under Conditions of Reduced Viral Challenge (cid:1)

N. Parkin, M. Krystal, R. Colonno, 2008 .

Genotypic correlates of susceptibility to HIV-1 attachment inhibitor BMS-626529, the active agent of the prodrug BMS-663068.

D. Langley, M. Krystal, N. Ray, 2014, The Journal of antimicrobial chemotherapy.

Inhibitors of human immunodeficiency virus type 1 (HIV-1) attachment. 5. An evolution from indole to azaindoles leading to the discovery of 1-(4-benzoylpiperazin-1-yl)-2-(4,7-dimethoxy-1H-pyrrolo[2,3-c]pyridin-3-yl)ethane-1,2-dione (BMS-488043), a drug candidate that demonstrates antiviral activity

N. Meanwell, R. Colonno, J. Kadow, 2009, Journal of medicinal chemistry.

Inhibitors of HIV-1 Attachment: The Discovery and Development of Temsavir and its Prodrug Fostemsavir.

Martin D. Eastgate, N. Meanwell, D. Langley, 2018, Journal of medicinal chemistry.

In Vitro Antiviral Characteristics of HIV-1 Attachment Inhibitor BMS-626529, the Active Component of the Prodrug BMS-663068

N. Meanwell, M. Krystal, J. Kadow, 2012, Antimicrobial Agents and Chemotherapy.

In Vivo Patterns of Resistance to the HIV Attachment Inhibitor BMS-488043

D. Langley, L. Alexander, M. Krystal, 2010, Antimicrobial Agents and Chemotherapy.

Resistance Mutations (NRTI) BMS-986001 against Known NRTI Nucleoside Reverse Transcriptase Inhibitor Cross-Resistance Profile of In Vitro

M. Krystal, G. Hanna, Tricia L. Protack, 2014 .

In Vitro Cross-Resistance Profile of Nucleoside Reverse Transcriptase Inhibitor (NRTI) BMS-986001 against Known NRTI Resistance Mutations

M. Krystal, G. Hanna, Tricia L. Protack, 2013, Antimicrobial Agents and Chemotherapy.

Design, Synthesis, and SAR of C-3 Benzoic Acid, C-17 Triterpenoid Derivatives. Identification of the HIV-1 Maturation Inhibitor 4-((1 R,3a S,5a R,5b R,7a R,11a S,11b R,13a R,13b R)-3a-((2-(1,1-Dioxidothiomorpholino)ethyl)amino)-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)-2,3,3a,4,5,5a,5b,6,7,7a,8,1

B. Beno, N. Meanwell, V. Arora, 2018, Journal of medicinal chemistry.

The design, synthesis and structure-activity relationships associated with C28 amine-based betulinic acid derivatives as inhibitors of HIV-1 maturation.

N. Meanwell, Zeyu Lin, M. Krystal, 2018, Bioorganic & medicinal chemistry letters.

Inhibitors of HIV-1 maturation: Development of structure-activity relationship for C-28 amides based on C-3 benzoic acid-modified triterpenoids.

N. Meanwell, M. Krystal, Tricia L. Protack, 2016, Bioorganic & medicinal chemistry letters.

C-3 benzoic acid derivatives of C-3 deoxybetulinic acid and deoxybetulin as HIV-1 maturation inhibitors.

B. Beno, N. Meanwell, Zeyu Lin, 2016, Bioorganic & medicinal chemistry.

C-3 benzoic acid derivatives of C-3 deoxybetulinic acid and deoxybetulin as HIV-1 maturation inhibitors.

B. Beno, N. Meanwell, Zeyu Lin, 2016, Bioorganic & medicinal chemistry.

Genotypic correlates of susceptibility to HIV-1 attachment inhibitor BMS-626529, the active agent of the prodrug BMS-663068.

D. Langley, M. Krystal, N. Ray, 2014, The Journal of antimicrobial chemotherapy.