D. Nazareno

发表

Piperazine-based CCR5 antagonists as HIV-1 inhibitors. I: 2(S)-methyl piperazine as a key pharmacophore element.

S. Mccombie, J. Tagat, J. Liu, 2001, Bioorganic & medicinal chemistry letters.

Synthesis of mono- and difluoronaphthoic acids.

H. Josien, Y. Wang, J. Tagat, 2002, The Journal of organic chemistry.

GENERATION AND IN SITU ACYLATION OF ENAMINONE ANIONS : A CONVENIENT SYNTHESIS OF 3-CARBETHOXY-4(1H)-PYRIDINONES AND -4-PYRONES AND RELATED COMPOUNDS

W. Metz, J. Tagat, B. Shankar, 1991 .

Synthesis and chemistry of thia-analogs of the anti-mitotic podophyllium lignans

W. Metz, J. Tagat, M. Puar, 1993 .

Synthesis and structure-activity relationships of M(2)-selective muscarinic receptor ligands in the 1-[4-(4-arylsulfonyl)-phenylmethyl]-4-(4-piperidinyl)-piperazine family.

J. Lachowicz, T. Asberom, J. Tagat, 2002, Bioorganic & medicinal chemistry letters.

Synthesis and anti-herpes activity of some a-ring functionalized dehydroabietane derivatives

A. Ganguly, J. Tagat, M. Puar, 1994 .

Piperazine-based CCR5 antagonists as HIV-1 inhibitors. II. Discovery of 1-[(2,4-dimethyl-3-pyridinyl)carbonyl]-4- methyl-4-[3(S)-methyl-4-[1(S)-[4-(trifluoromethyl)phenyl]ethyl]-1-piperazinyl]- piperidine N1-oxide (Sch-350634), an orally bioavailable, potent CCR5 antagonist.

B. Neustadt, K. Cox, M. Murray, 2001, Journal of medicinal chemistry.

Metabolic stabilization of benzylidene ketal M(2) muscarinic receptor antagonists via halonaphthoic acid substitution.

W. Greenlee, J. Lachowicz, J. Clader, 2001, Bioorganic & medicinal chemistry letters.

Piperazine-based CCR5 antagonists as HIV-1 inhibitors. IV. Discovery of 1-[(4,6-dimethyl-5-pyrimidinyl)carbonyl]- 4-[4-[2-methoxy-1(R)-4-(trifluoromethyl)phenyl]ethyl-3(S)-methyl-1-piperazinyl]- 4-methylpiperidine (Sch-417690/Sch-D), a potent, highly selective, and orally bioavailable CCR5 antagonis

J. Lachowicz, K. Cox, G. Varty, 2004, Journal of medicinal chemistry.

Concise formation of 4-benzyl piperidines and related derivatives using a Suzuki protocol.

M. Miller, A. Palani, A. Bauer, 2001, The Journal of organic chemistry.