J. Saez

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Corticotropin positively regulates its own receptors and cAMP response in cultured bovine adrenal cells.

A. Penhoat, C. Jaillard, J. Saez, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Identification and characterization of corticotropin receptors in bovine and human adrenals

A. Penhoat, C. Jaillard, J. Saez, 1993, The Journal of Steroid Biochemistry and Molecular Biology.

Regulation of corticotropin receptor number and messenger RNA in cultured human adrenocortical cells by corticotropin and angiotensin II.

D. Naville, M. Lebrethon, J. Saez, 1994, The Journal of clinical investigation.

Cycloheximide enhances ACTH-receptor mRNA through transcriptional and post-transcriptional mechanisms in bovine adrenocortical cells

A. Penhoat, P. Durand, C. Jaillard, 1996, Molecular and Cellular Endocrinology.

Characterization of the human ACTH receptor gene and in vitro expression.

S. Fontanay, A. Penhoat, D. Naville, 1996, Endocrine research.

Regulation of corticotropin and steroidogenic enzyme mRNAs in human fetal adrenal cells by corticotropin, angiotensin-II and transforming growth factor β1

D. Naville, M. Lebrethon, C. Jaillard, 1994, Molecular and Cellular Endocrinology.

Terminal differentiation of Sol 8 myoblasts is retarded by a transforming growth factor-beta autocrine regulatory loop.

S. Allégra, J. Saez, Jacques-Yuan Li, 2004, The Biochemical journal.

Repression of Transforming Growth Factor 1 Protein by Antisense Oligonucleotide-induced Increase of Adrenal Cell Differentiated Functions (*)

C. Le Roy, P. Leduque, P. Dubois, 1996, The Journal of Biological Chemistry.

Characterisation of the muscarinic receptor subtype M3 in the bovine zona fasciculata-reticularis cells by receptor binding, mRNA and functional studies.

J. Y. Li, J. Saez, A. Janossy, 1999, The Journal of endocrinology.

Processing of human choriogonadotropin and its receptors by cultured pig Leydig cells. Role of cyclic AMP and protein synthesis.

M. Bernier, J. Saez, M. Clerget, 1986, European journal of biochemistry.

Processing of follitropin and its receptor by cultured pig Sertoli cells. Effect of monensin.

C. Jaillard, J. Saez, 1986, European journal of biochemistry.

The outer membrane protein X from Escherichia coli exhibits immune properties.

T. Nguyen, Y. Delneste, P. Jeannin, 2003, Vaccine.

Angiotensin II potentiates agonist-induced 3',5'-cyclic adenosine monophosphate production by cultured bovine adrenal cells through protein kinase C and calmodulin pathways.

C. Jaillard, J. Saez, M. Bégeot, 1992, Endocrinology.

Angiotensin‐II‐induced expression of proto‐oncogene (c‐fos, jun‐B and c‐jun) mRNA in bovine adrenocortical fasciculata cells (BAC) is mediated by AT‐1 receptors

C. Jaillard, J. Saez, I. Viard, 1992, FEBS letters.

[Paracrine regulation of Leydig cells].

R. Habert, J. Saez, F. Chuzel, 1996, Annales d'endocrinologie.

The interaction of hCG with rat adipose tissue: Apparent lack of hCG-LH receptors

F. Haour, J. Saez, G. Tell, 1977, Molecular and Cellular Endocrinology.

Hormonal control of Leydig cell function.

M. Benahmed, J. Reventós, J. Saez, 1984 .

Effects of proopiomelanocortin-derived peptides, methionine-enkephalin and forskolin on the maturation of ovine fetal adrenal cells in culture.

N. Seidah, M. Chrétien, P. Durand, 1984, Biology of reproduction.

Effects of several pro-opiomelanocortin derived peptides on steroidogenesis in ovine and bovine adrenal cells.

M. Chrétien, P. Durand, A. Cathiard, 1985, Journal of steroid biochemistry.

In vitro maturation of ovine fetal adrenal cells adenylate cyclase: corticotropin-dependent and independent development of the response to corticotropin.

P. Durand, A. Cathiard, J. Saez, 1982, Biochemical and biophysical research communications.

ACTH induction of the maturation of ACTH-sensitive adenylate cyclase system in the ovine fetal adrenal.

A. Locatelli, P. Durand, A. Cathiard, 1981, Journal of steroid biochemistry.

Maturation of adrenocorticotropin-sensitive adenylate cyclase of ovine fetal adrenal during late pregnancy.

P. Durand, A. Morera, A. Cathiard, 1981, Endocrinology.

In vitro maturation of steroidogenic capacity of ovine fetal and neonatal adrenal cells.

P. Durand, A. Cathiard, J. Saez, 1984, Endocrinology.

Modifications of the steroidogenic pathway during spontaneous and adrenocorticotropin-induced maturation of ovine fetal adrenal.

A. Locatelli, P. Durand, A. Cathiard, 1982, Endocrinology.

Hormonal regulation of membrane receptors and cell responsiveness: a review.

F. Haour, J. Saez, G. Tell, 1978, Metabolism: clinical and experimental.

Transforming growth factor-β inhibits steroid 17α-hydroxylase cytochrome P-450 expression in ovine adrenocortical cells

R. Magness, W. Rainey, J. Mason, 1990 .

Regulation of c-fos, c-jun, jun-B, and c-myc messenger ribonucleic acids by gonadotropin and growth factors in cultured pig Leydig cell.

S. Hall, J. Saez, M. Berthelon, 1991, Endocrinology.

The paracrine role of Sertoli cells on Leydig cell function

P. Chatelain, P. Chatelain, J. Saez, 1992, Cell Biology and Toxicology.

Control of production of insulin-like growth factor I by pig Leydig and Sertoli cells cultured alone or together. Cell-cell interactions

P. Chatelain, D. Naville, J. Saez, 1990, Molecular and Cellular Endocrinology.

Regulation of IGF-I receptors by corticotropin and angiotensin-II in cultured bovine adrenocortical cells.

A. Penhoat, I. Louveau, J. Saez, 1989, Biochemical and biophysical research communications.

Differentiating effects of somatomedin-C/insulin-like growth factor I and insulin on Leydig and Sertoli cell functions.

P. Chatelain, D. Naville, C. Jaillard, 1988, Reproduction, nutrition, developpement.

Characterization and regulation of somatomedin-C/insulin-like growth factor I (Sm-C/IGF-I) receptors on cultured pig Leydig cells. Effects of Sm-C/IGF-I on luteotropin receptors and steroidogenesis.

P. Chatelain, C. Jaillard, J. Saez, 1987, European journal of biochemistry.

Regulation of gonadotropin receptors, gonadotropin responsiveness, and cell multiplication by somatomedin‐C and insulin in cultured pig Leydig cells

M. Bernier, P. Chatelain, J. Saez, 1986, Journal of cellular physiology.

Leydig-Cell Responsiveness to LH-hCG Stimulation: Mechanisms of hCG- and Steroid-Induced Refractoriness

F. Haour, J. Saez, 1978 .

Adrenocorticotropin regulates angiotensin II receptors in bovine adrenal cells in vitro.

M. Chauvin, A. Morera, J. Saez, 1984, Biochemical and biophysical research communications.

Time-course effects of human recombinant luteinizing hormone on porcine Leydig cell specific differentiated functions

J. Saez, F. Chuzel, H. Lejeune, 1998, Molecular and Cellular Endocrinology.

Opposite effects of angiotensin-II and corticotropin on bovine adrenocortical cell steroidogenic responsiveness

J. Saez, M. Bégeot, D. Langlois, 1991, Molecular and Cellular Endocrinology.

The influence of plasma lipoproteins on steroidogenesis of cultured ovine fetal and neonatal adrenal cells.

P. Durand, A. Cathiard, J. Saez, 1987, Journal of steroid biochemistry.

Adrenal cholesterol‐binding protein: Properties and partial purification

A. Morera, J. Saez, A. Lefèvre, 1978, FEBS letters.

Regulation of gonadotropin receptors and steroidogenesis in cultured porcine Leydig cells.

F. Haour, J. Mather, J. Saez, 1982, Endocrinology.

Expression and regulation of two steps of steroidogenesis in human Leydig cells x murine cell line clone 1D hybrids.

A. Crozat, J. Saez, C. Finaz, 1982, Biochemical and biophysical research communications.

Leydig cells: endocrine, paracrine, and autocrine regulation.

J. Saez, 1994, Endocrine reviews.

Early hCG-induced desensitization in Leydig cells.

F. Haour, A. Cathiard, J. Saez, 1978, Biochemical and biophysical research communications.

Human cultured adrenal fasciculata-reticularis cells are targets for angiotensin-II: effects on cytochrome P450 cholesterol side-chain cleavage, cytochrome P450 17 alpha-hydroxylase, and 3 beta-hydroxysteroid-dehydrogenase messenger ribonucleic acid and proteins and on steroidogenic responsiveness t

G. Defayes, M. Lebrethon, C. Jaillard, 1994, The Journal of clinical endocrinology and metabolism.

Characterization and regulation of the angiotensin II type‐1 receptor (binding and mRNA) in human adrenal fasciculata‐reticularis cells

R. Benarous, E. Rouer, D. Naville, 1993, FEBS letters.

Characterization and coupling of angiotensin-II receptor subtypes in cultured bovine adrenal fasciculata cells

A. Penhoat, J. Saez, S. Poulette, 1992, The Journal of Steroid Biochemistry and Molecular Biology.

Human proopiomelanocortin-(79-96), a proposed cortical androgen-stimulating hormone, does not affect steroidogenesis in cultured human adult adrenal cells.

A. Penhoat, C. Jaillard, J. Saez, 1991, The Journal of clinical endocrinology and metabolism.

Ovine adrenal fasciculata cells contain angiotensin-II receptors coupled to intracellular effectors but are resistant to the steroidogenic effects of this hormone.

W. Rainey, A. Capponi, J. Saez, 1990, Endocrinology.

Regulation of angiotensin II receptors and steroidogenic responsiveness in cultured bovine fasciculata and glomerulosa adrenal cells.

A. Crozat, A. Penhoat, C. Jaillard, 1988, European journal of biochemistry.

Processing of angiotensin II (A-II) and (Sar1,Ala8)A-II by cultured bovine adrenocortical cells.

A. Crozat, A. Penhoat, J. Saez, 1986, Endocrinology.

Transcription and post-transcriptional regulation of luteotropin/chorionic gonadotropin receptor by the agonist in Leydig cells.

H. Schteingart, J. Saez, F. Chuzel, 1995, European journal of biochemistry.

Insulin-Like Growth Factor I Receptors Are Expressed by the Enteroendocrine Cell Line STC-1: Relationship with Proliferation and Cholecystokinin Expression

J. Chayvialle, J. Saez, J. Cuber, 1998, Hormone Research in Paediatrics.

Characterization of insulin-like growth factor I and insulin receptors on cultured bovine adrenal fasciculata cells. Role of these peptides on adrenal cell function.

P. Chatelain, A. Penhoat, C. Jaillard, 1988, Endocrinology.

Transcriptional regulation of the lutropin/human choriogonadotropin receptor and three enzymes of steroidogenesis by growth factors in cultured pig Leydig cells.

J. Saez, F. Chuzel, Ann M. Clark, 1996, European journal of biochemistry.

In vitro regulation of pig Sertoli cell growth and function: effects of fibroblast growth factor and somatomedin-C.

P. Chatelain, C. Jaillard, J. Saez, 1987, Biology of reproduction.

Sertoli Cell-Germ Cell Interactions and TGFβ1 Expression and Secretionin Vitro

B. Jégou, J. Saez, M. Vigier, 1997 .

The immunohistochemical localization of transforming growth factor-β2 in the fetal and neonatal rat testis

R. Habert, R. Olaso, J. Saez, 1997, Molecular and Cellular Endocrinology.

Glucocorticoid receptors in interstitial cells of the rat testis.

A. Morera, J. Saez, D. Evain, 1976, Journal of steroid biochemistry.

Hormonal regulation of proteins secreted by cultured pig Sertoli cells: characterization by two-dimensional polyacrylamide gel electrophoresis

J. Saez, A. Dazord, M. Perrard-Sapori, 1985, Molecular and Cellular Endocrinology.

Growth hormone and insulin-like growth factor I treatment increase testicular luteinizing hormone receptors and steroidogenic responsiveness of growth hormone deficient dwarf mice.

J. Saez, P. Sanchez, P. Chatelain, 1991, Endocrinology.

Transforming growth factor β1 inhibits steroidogenesis in dispersed fetal testicular cells in culture 1 This work was supported by INSERM and Université Paris 7 1

R. Habert, J. Saez, C. Levacher, 1997, Molecular and Cellular Endocrinology.

Interaction of vasoactive intestinal peptide (VIP) with a mouse adrenal cell line (Y-1): specific binding and biological effects.

M. Laburthe, A. Morera, A. Cathiard, 1979, Biochemical and biophysical research communications.

Modulation of cultured mouse leydig cells adenylate cyclase by forskolin and hCG

A. Lefèvre, J. Saez, M. Berthelon, 1985, Molecular and Cellular Endocrinology.

Developmental changes in testosterone production by the rat testis in vitro during late fetal life.

V. Rouiller-Fabre, R. Habert, J. Saez, 1992, Archives of andrology.

Glucocorticoid-suppressible hyperaldosteronism and adrenal tumors occurring in a single French pedigree.

X. Jeunemaître, C. Gomez-Sanchez, P. Corvol, 1995, The Journal of clinical investigation.

Demonstration by transfection studies that mutations in the adrenocorticotropin receptor gene are one cause of the hereditary syndrome of glucocorticoid deficiency.

D. Faury, D. Naville, L. Barjhoux, 1996, The Journal of clinical endocrinology and metabolism.

Food-dependent Cushing's syndrome: characterization and functional role of gastric inhibitory polypeptide receptor in the adrenals of three patients.

T. Usdin, Y. Reznik, G. Narboni, 1998, The Journal of clinical endocrinology and metabolism.

Interactions between immature porcine Leydig and Sertoli cells in vitro

M. Benahmed, E. Tabone, J. Reventós, 1984, Cell and Tissue Research.

Melanocortins and Adrenocortical Function

J. Saez, M. Bégeot, 2000 .

Regulation of primary response and specific genes in adrenal cells by peptide hormones and growth factors

A. Penhoat, J. Saez, I. Viard, 1996, Steroids.

Regulation by growth factors (IGF‐I, b‐FGF and TGF‐β) of protooncogene mRNA, growth and differentiation of bovine adrenocortical fasciculata cells

C. Jaillard, J. Saez, I. Viard, 1993, FEBS letters.

Angiotensin II (A-II) steroidogenic refractoriness in Y-1 cells in the presence of A-II receptors negatively coupled to adenylate cyclase.

I. Vilgrain, J. Saez, M. Bégeot, 1987, Endocrine research.

In vitro stimulation and inhibition of adrenocorticotropin release by pituitary cells from ovine fetuses and lambs.

F. Dacheux, P. Durand, A. Cathiard, 1986, Endocrinology.

Carbachol induces homologous steroidogenic refractoriness of bovine fasciculata-reticularis cells

J. Y. Li, J. Saez, A. Janossy, 2001, Molecular and Cellular Endocrinology.

Regulation by Adrenocorticotropin (ACTH), Angiotensin II, Transforming Growth Factor-β, and Insulin-Like Growth Factor I of Bovine Adrenal Cell Steroidogenic Capacity and Expression of ACTH Receptor, Steroidogenic Acute Regulatory Protein, Cytochrome P450c17, and 3β-Hydroxysteroid Dehydrogenase.

C. Le Roy, C. Roy, D. Stocco, 2000, Endocrinology.

Enhancement of long-term testosterone secretion and steroidogenic enzyme expression in human Leydig cells by co-culture with human Sertoli cell-enriched preparations.

J. Saez, H. Lejeune, P. Sanchez, 2005, International journal of andrology.

Enhancement of long-term testosterone secretion and steroidogenic enzyme expression in human Leydig cells by co-culture with human Sertoli cell-enriched preparations

J. Saez, H. Lejeune, P. Sanchez, 1998 .

Stimulating effect of both human recombinant inhibin A and activin A on immature porcine Leydig cell functions in vitro.

J. Mather, J. Saez, F. Chuzel, 1997, Endocrinology.

Transforming growth factor β inhibits Leydig cell functions

J. Saez, M. Vigier, O. Avallet, 1987 .

Paracrine and Autocrine Regulation of Insulin‐Like Growth Factor I

A. Penhoat, D. Naville, C. Jaillard, 1991, Acta paediatrica Scandinavica. Supplement.

Specific Receptors for IGF‐I on Cultured Bovine Adrenal Cells: Hormonal Regulation of IGF‐I Secretion by these Cells

P. Chatelain, A. Penhoat, D. Naville, 1988 .

Somatomedin-C/insulin-like growth factor 1: a differentiating factor of testicular function.

D. Naville, C. Jaillard, J. Saez, 1987, International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology.

Stimulatory and inhibitory effects of protein kinase C activation and calcium ionophore on cultured pig Leydig cells.

M. Bernier, J. Saez, M. Berthelon, 1987, European journal of biochemistry.

Expression and Effect of Insulin-Like Growth Factor I on Rat Fetal Leydig Cell Function and Differentiation.

V. Rouiller-Fabre, R. Habert, J. Saez, 1998, Endocrinology.

In vitro effect of insulin and insulin-like growth factor-I on cell multiplication and adrenocorticotropin responsiveness of fetal adrenal cells.

P. Chatelain, P. Durand, J. Saez, 1989, Biology of reproduction.

Effects of transforming growth factor-beta 1 on human adrenocortical fasciculata-reticularis cell differentiated functions.

D. Naville, M. Lebrethon, C. Jaillard, 1994, The Journal of clinical endocrinology and metabolism.

Receptor Subtypes in Cultured Bovine and Human Adrenal Fasciculata Cells and PC 12 W Cells

M. Lebrethon, J. Saez, R. Ouali, 1993 .

Modulation of Leydig cell functions by culture with Sertoli cells or with Sertoli cell-conditioned medium: effect of insulin, somatomedin-C and FSH

P. Chatelain, J. Saez, N. Rogemond, 1987, Molecular and Cellular Endocrinology.

Changes in protein kinase activities in lamb adrenals at late gestation and early postnatal stages

E. Chambaz, P. Durand, I. Vilgrain, 1987, Molecular and Cellular Endocrinology.

PATTERN OF PLASMA LEVELS OF CORTISOL, DEHYDROEPIANDROSTERONE AND PREGNENOLONE SULPHATE IN NORMAL SUBJECTS AND IN PATIENTS WITH HOMOZYGOUS FAMILIAL HYPERCHOLESTEROLAEMIA DURING ACTH INFUSION

R. Boizel, M. Bost, A. Cathiard, 1986, Clinical endocrinology.

Hormonal regulation of pig Leydig cells in culture.

M. Benahmed, J. Reventós, F. Haour, 1983, Journal of steroid biochemistry.

Steroidogenesis of cultured purified pig Leydig cells: effects of lipoproteins and human chorionic gonadotropin.

M. Benahmed, J. Reventós, J. Saez, 1983, Endocrinology.

Regulation of bovine adrenal cell corticotropin receptor mRNA levels by corticotropin (ACTH) and angiotensin-II (A-II)

A. Penhoat, C. Jaillard, J. Saez, 1994, Molecular and Cellular Endocrinology.

Estrogen-like compounds and progesterone in male and female rats before puberty--II. Effects of administration of ACTH, steroidogenesis inhibitors, dexamethasone and hCG.

J. Bertrand, A. Morera, J. Saez, 1978, Journal of steroid biochemistry.

Estrogen-like compounds and progesterone in male and female rats before puberty--I. Pattern and origin.

J. Bertrand, A. Morera, J. Saez, 1978, Journal of steroid biochemistry.

Effects of ACTH on protein synthesis in rat adrenal analyzed by two dimensional gel electrophoresis.

J. Saez, A. Dazord, D. Langlois-Gallet, 1984, Journal of steroid biochemistry.

Somatomedin-C/insulin-like growth factor 1-like material secreted by porcine Sertoli cells in vitro: characterization and regulation.

P. Chatelain, D. Naville, J. Saez, 1987, Biochemical and biophysical research communications.

Human corticotropin-releasing factor type 1 receptor analysis with white blood cells mRNAs and DNA

M. Nicolino, R. Besançon, J. Saez, 2003, Molecular and Cellular Endocrinology.

Insulin-like growth factor-I and insulin increase the stimulatory guanine nucleotide binding protein (Gs) in cultured bovine adrenal cells

J. Saez, M. Bégeot, D. Langlois, 1989, Molecular and Cellular Endocrinology.

Transcriptional and translational regulation of angiotensin II type 2 receptor by angiotensin II and growth factors.

J. Y. Li, J. Saez, M. Berthelon, 1999, Endocrinology.

Regulation of cell proliferation and angiotensin II type 2 receptors in R3T3 cells.

J. Y. Li, J. Saez, M. Berthelon, 1998, Endocrine research.

Regulation by growth factors of angiotensin II type-1 receptor and the alpha subunit of Gq and G11 in bovine adrenal cells.

J. Saez, M. Berthelon, A. Derrien, 1994, Endocrinology.

THE JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

E. Bosmans, B. Jégou, F. Ballet, 1997 .

hCG-induced prostaglandin E2 and F2α release in adult rat tests: Role in Leydig cell desensitization to hCG

F. Dray, F. Haour, J. Saez, 1979 .

Regulation of gonadotropin receptors on cultured porcine Leydig and Sertoli cells: effect of potassium depletion.

M. Bernier, B. Laferrère, C. Jaillard, 1986, Endocrinology.

Testis, Epididymis and Technologies in the Year 2000

C. Pineau, B. Jégou, J. Saez, 2013, Ernst Schering Research Foundation Workshop.

Hormonal modulation of protein degradation in Y-1 adrenal cells.

Y. Morel, J. Saez, A. Dazord, 1980, Journal of steroid biochemistry.

Characterization and regulation of angiotensin and corticotropin receptors on cultured bovine adrenal cells.

A. Penhoat, C. Jaillard, J. Saez, 1991, Endocrine research.

Gonadotropin stimulation of pregnenolone metabolism in Chinese Hamster Ovary cells in culture

W. Anderson, J. Saez, D. Evain, 1981, Journal of cellular physiology.

Origin, differentiation and regulation of fetal and adult Leydig cells

R. Habert, J. Saez, H. Lejeune, 2001, Molecular and Cellular Endocrinology.

Cultured Sertoli cell-mediated FSH stimulatory effect on Leydig cell steroidogenesis.

M. Benahmed, E. Tabone, J. Reventós, 1985, The American journal of physiology.

Development of the fetal pituitary-adrenal axis in the sheep.

P. Durand, A. Cathiard, H. Darbeida, 1988, Reproduction, nutrition, developpement.

Corticotropin and angiotensin induce dephosphorylation of a Mr-20,000 protein in bovine adrenal cells.

J. Saez, P. Deviller, P. Vallier, 1987, Endocrine research.

Spontaneous and adrenocorticotropin (ACTH)-induced maturation of the responsiveness of ovine fetal adrenal cells to in vitro stimulation by ACTH and cholera toxin.

A. Locatelli, P. Durand, A. Cathiard, 1981, Endocrinology.

Autocrine regulation of Leydig cell differentiated functions by insulin-like growth factor I and transforming growth factor beta

C. Roy, J. Saez, F. Chuzel, 1999, The Journal of Steroid Biochemistry and Molecular Biology.

Origin, proliferation and differentiation of Leydig cells.

R. Habert, J. Saez, H. Lejeune, 1998, Journal of molecular endocrinology.

Stimulation of aromatase activity in immature porcine Leydig cells by fibroblast growth factor (FGF).

J. Saez, M. Berthelon, P. Sanchez, 1988, Biochemical and biophysical research communications.

Testicular steroidogenesis after human chorionic gonadotropin desensitization in rats.

F. Haour, J. Saez, F. Chasalow, 1979, The Journal of biological chemistry.

Studies with purified immature porcine Leydig cells in primary culture.

M. Bernier, W. Gibb, F. Haour, 1983, Biology of reproduction.

Androgen production in primary culture of immature porcine leydig cells

M. Bernier, F. Haour, J. Mather, 1983, Molecular and Cellular Endocrinology.

Paracrine regulation of testicular function.

P. Chatelain, E. Tabone, M. Rivarola, 1987, Journal of steroid biochemistry.

Adrenal adenylate cyclase and steroidogenic activities of 63 day old ovine fetuses: in vitro effects of ACTH1-24 and forskolin.

P. Durand, A. Cathiard, J. Saez, 1987, Biochimie.

Modification of steroidogenesis in a mouse adrenal cell line (Y-1) transformed by simian adenovirus SA-7

P. Tournier, D. Mathieu, J. Saez, 1981, Steroids.

Stimulation of ribonucleic acid and deoxyribonucleic acid synthesis in spermatogenic cells by their coculture with Sertoli cells.

M. Rivarola, J. Saez, P. Sanchez, 1985, Endocrinology.

Stimulatory effect of follicle-stimulating hormone on basal and luteinizing hormone-stimulated testosterone secretions by the fetal rat testis in vitro.

V. Rouiller-Fabre, R. Habert, J. Saez, 1993, Endocrinology.

Effects of in vivo administration of dexamethasone, corticotropin and human chorionic gonadotropin on steroidogenesis and protein and DNA synthesis of testicular interstitial cells in prepuberal rats.

F. Haour, A. Morera, J. Saez, 1977, Endocrinology.

Prostaglandin receptors in human and ovine adrenal glands: binding and stimulation of adenyl cyclase in subcellular preparations.

J. Bertrand, A. Morera, J. Saez, 1974, Endocrinology.

Role of cyclic AMP and protein kinase on the steroidogenic action of ACTH, prostaglandin E1 and dibutyryl cyclic AMP in normal adrenal cells and adrenal tumor cells from humans.

J. Saez, D. Evain, D. Gallet, 1978, Journal of cyclic nucleotide research.

Inhibitory or stimulatory effect of human genes on the expression of adrenal function in human Leydig X Y1 cell hybrids.

A. Crozat, J. Saez, C. Finaz, 1985, Journal of steroid biochemistry.

Primary cultures of Leydig cells from rat, mouse and pig: Advantages of porcine cells for the study of gonadotropin regulation of Leydig cell function

F. Haour, J. Mather, J. Saez, 1981, Steroids.

Kinetics of Human Chorionic Gonadotropin-Induced Steroidogenic Response of the Human Testis. II. Plasma 17α-Hydroxyprogesterone, Δ4-Androstenedione, Estrone, and 17β-Estradiol: Evidence for the Action of Human Chorionic Gonadotropin on Intermediate Enzymes Implicated in Steroid Biosynthesis*

M. Forest, J. Saez, A. Lecoq, 1979 .

Expression and regulation of transforming growth factor-beta 1 messenger ribonucleic acid and protein in cultured porcine Leydig and Sertoli cells.

P. Leduque, P. Dubois, J. Saez, 1994, Endocrinology.

Oestrogen induced Leydig cell refractoriness to gonadotrophin stimulation.

F. Haour, A. Cathiard, J. Saez, 1978, Acta endocrinologica.

Sertoli‐Leydig Cell Communications a

D. Naville, J. Saez, O. Avallet, 1989, Annals of the New York Academy of Sciences.

Activation of microsomal cAMP-dependent protein kinase isoenzyme I by ACTH1-24 in bovine adrenal cells.

J. Saez, P. Deviller, P. Vallier, 1985, Journal of steroid biochemistry.

Enhancement of testosterone secretion by normal adult human Leydig cells by co-culture with enriched preparations of normal adult human Sertoli cells.

H Lejeune, M Skalli, P Sanchez, 1993, International journal of andrology.

Induction by LH/hCG of an Increase in the Rate of Pig Leydig Cell Receptor mRNA Degradation

H. Schteingart, J. Saez, F. Chuzel, 1994 .

hCG-Dependent regulation of gonadotropin receptor sites: Negative control in testicular leydig cells

F. Haour, J. Saez, 1977, Molecular and Cellular Endocrinology.

Gonadotropin receptor regulation in hypophysectomized rat Leydig cells.

A. Cathiard, J. Saez, P. Sanchez, 1978, Biochemical and biophysical research communications.

Testicular Steroidogenesis after hCG Desensitization in Rats

F. Haour, J. Saez, F. Chasalow, 1978 .

Human chorionic gonadotropin-induced Leydig cell refractoriness to gonadotropin stimulation.

F. Haour, J. Saez, G. Tell, 1978, Molecular pharmacology.

Synergistic Effects of Sertoli Cell and FSH on Leydig Cell Function: In Vitro Study

M. Benahmed, E. Tabone, J. Reventós, 1984, Annals of the New York Academy of Sciences.

De novo synthesis of cholesterol by ovine fetal and neonatal adrenocortical cells

P. Durand, A. Cathiard, J. Saez, 1988, Molecular and Cellular Endocrinology.

Gap junction-mediated cell-to-cell communication in bovine and human adrenal cells. A process whereby cells increase their responsiveness to physiological corticotropin concentrations.

B. Rousset, M. Lebrethon, J. Saez, 1995, The Journal of clinical investigation.

ACTH and prostaglandin receptors in human adrenocortical tumors. Apparent modification of a specific component of the ACTH-binding site.

J. Saez, A. Dazord, D. Gallet, 1975, The Journal of clinical investigation.

Characterization of the transcription start site of the ACTH receptor gene: presence of an intronic sequence in the 5'-flanking region

D. Naville, L. Barjhoux, M. Lebrethon, 1994, Molecular and Cellular Endocrinology.

Effects of fetal hypophysectomy and the in vitro treatment by pituitary extracts on the maturation of cultured ovine fetal adrenal cells.

A. Locatelli, P. Durand, A. Cathiard, 1985, Endocrinology.

ACTH and angiotensin II regulation of insulin-like growth factor-I and its binding proteins in cultured bovine adrenal cells.

P. Chatelain, A. Penhoat, P. Leduque, 1991, Journal of molecular endocrinology.

Maturation of steroidogenic cells: a target for IGF-I.

A. Penhoat, D. Naville, C. Jaillard, 1988, Acta paediatrica Scandinavica. Supplement.

Response of plasma testosterone to human chorionic gonadotropin stimulation in the ram.

F. Garnier, J. Saez, 1980, Biology of reproduction.

Distribution and characterization of camp-dependent protein kinase isoenzymes in bovine adrenal cells

J. Saez, J. Bata, P. Deviller, 1984, Molecular and Cellular Endocrinology.

Regulation by growth factors og leydig cell differentiated functions

P. Chatelain, J. Saez, M. Vigier, 1991, The Journal of Steroid Biochemistry and Molecular Biology.

Cell-cell communication in the testis.

P. Chatelain, J. Saez, H. Lejeune, 1991, Hormone research.

Regulation of pig Leydig cell aromatase activity by gonadotropins and Sertoli cells.

J. Saez, M. Berthelon, O. Avallet, 1989, Biology of reproduction.

Steroidogenesis of cultured purified pig leydig cells: Secretion and effects of estrogens

M. Bernier, M. Benahmed, J. Saez, 1982, Molecular and Cellular Endocrinology.

Immunohistochemical localization of transforming growth factor-β 1 in the fetal and neonatal rat testis

V. Rouiller-Fabre, R. Habert, J. Saez, 1994, Molecular and Cellular Endocrinology.

Transforming growth factor-beta inhibits steroid 17 alpha-hydroxylase cytochrome P-450 expression in ovine adrenocortical cells.

R. Magness, W. Rainey, J. Mason, 1990, Endocrinology.

Overexpression of a dominant-negative type II TGFβ receptor tagged with green fluorescent protein inhibits the effects of TGFβ on cell growth and gene expression of mouse adrenal tumor cell line Y-1 and enhances cell tumorigenicity

C. Roy, P. Leduque, J. Y. Li, 1999, Molecular and Cellular Endocrinology.

Effects of transforming growth factor beta on ovine adrenocortical cells

E. Chambaz, W. Rainey, J. Mason, 1988, Molecular and Cellular Endocrinology.

The potentiating effects of phorbol ester on ACTH-, cholera toxin-, and forskolin-induced cAMP production by cultured bovine adrenal cells is not mediated by the inactivation of alpha subunit of Gi protein.

J. Saez, M. Bégeot, D. Langlois, 1987, Biochemical and biophysical research communications.

Regulation by gonadotropins of the messenger ribonucleic acid for P450 side-chain cleavage, P450(17) alpha-hydroxylase/C17,20-lyase, and 3 beta-hydroxysteroid dehydrogenase in cultured pig Leydig cells.

J. Saez, F. Chuzel, A. Clark, 1996, Biology of reproduction.

In vitro interactions between Sertoli cells and steroidogenic cells.

P. Chatelain, J. Saez, P. Vallier, 1986, Biochemical and biophysical research communications.

Adenosine 3', 5'-monophosphate-dependent protein kinase from normal human adrenal

J. Riou, J. Saez, D. Evain, 1977, Molecular and Cellular Endocrinology.

Is there a local IGF-system in human adrenocortical cells? 1 This study was supported by grant AL 332/2-1 and 2-2, Deutsche Forschungs-Gemeinschaft. 1

W. Blum, A. Penhoat, D. L'Allemand, 1998, Molecular and Cellular Endocrinology.

Regulation of ACTH receptor mRNA and binding sites by ACTH and angiotensin II in cultured human and bovine adrenal fasciculata cells.

A. Penhoat, M. Lebrethon, J. Saez, 1995, Endocrine research.

EGF-R as a hemopoietic growth factor receptor: The c-erbB product is present in chicken erythrocytic progenitors and controls their self-renewal

H. Kung, E. Lazarides, J. Samarut, 1991, Cell.

Angiotensin II Receptor Subtypes AT1 and AT2 Are Down-Regulated by Angiotensin II through AT1 Receptor by Different Mechanisms.

Rachida Ouali, Marie-Claude Berthelon, Martine Be Geot, 1997, Endocrinology.

Insulin-like growth factors enhance steroidogenic enzyme and corticotropin receptor messenger ribonucleic acid levels and corticotropin steroidogenic responsiveness in cultured human adrenocortical cells.

W. Oelkers, A. Penhoat, D. L'Allemand, 1996, The Journal of clinical endocrinology and metabolism.

Regulation of adrenal cell-differentiated functions by growth factors.

W. Rainey, A. Penhoat, J. Saez, 1994, Hormone research.

Retinoid-Sensitive Steps in Steroidogenesis in Fetal and Neonatal Rat Testes: In Vitro and In Vivo Studies

G. Livera, V. Rouiller-Fabre, R. Habert, 2004, Biology of reproduction.

Adrenal and testicular contribution to plasma oestrogens.

J. Bertrand, A. Morera, J. Saez, 1972, The Journal of endocrinology.

Expression and Regulation of Transforming Growth Factor β1 mRNA and Protein in Rat Fetal Testisin Vitro

R. Habert, J. Saez, C. Levacher, 1997 .

In vitro mitogenic and steroidogenic effects of ACTH analogues on an adrenal tumor cell line (Y-1).

A. Morera, J. Saez, 1980, Experimental cell research.

Transcriptional and translational regulation of angiotensin II type 2 receptor by angiotensin II and growth factors.

J. Y. Li, J. Saez, M. Berthelon, 1999, Endocrinology.

Hypersensitivity of the Adrenal Cortex to Trophic and Secretory Effects of Angiotensin II in Lyon Genetically-Hypertensive Rats

B. Claustrat, M. Lo, J. Sassard, 2004, Hypertension.

Regulation of guanine nucleotide binding regulatory proteins in cultured adrenal cells by adrenocorticotropin and angiotensin-II.

A. Spiegel, J. Saez, M. Bégeot, 1991, Endocrinology.

Involvement of the regulatory protein (Ns) in the maturation of ACTH-sensitive adenylate cyclase of ovine fetal adrenal during late gestation

P. Durand, A. Cathiard, J. Saez, 1985, Molecular and Cellular Endocrinology.

Antisense oligonucleotide targeting the transforming growth factor beta1 increases expression of specific genes and functions of Leydig cells.

C. Le Roy, P. Leduque, J. Saez, 1998, European journal of biochemistry.

Vitamin E prolongs survival and function of porcine Leydig cells in culture.

F. Dray, F. Haour, J. Mather, 1983, Acta endocrinologica.

Nuclear receptors Nor1 and NGFI-B/Nur77 play similar, albeit distinct, roles in the hypothalamo-pituitary-adrenal axis.

S. Cereghini, M. Zakin, F. Brunel, 2000, Endocrinology.

ACTH-induced change of cAMP-dependent protein-kinase repartition in bovine adrenal cells

J. Saez, P. Deviller, P. Vallier, 1982, Molecular and Cellular Endocrinology.

[Role of plasma lipoproteins in the function of steroidogenic tissues].

M. Benahmed, J. Reventós, J. Saez, 1983, Annales d'Endocrinologie.

Stable expression of normal and mutant human ACTH receptor Study of ACTH binding and coupling to adenylate cyclase

D. Naville, L. Barjhoux, P. Durand, 1997, Molecular and Cellular Endocrinology.

Ontogeny of the ACTH receptor, adenylate cyclase and steroidogenesis in adrenal

P. Durand, A. Cathiard, J. Saez, 1984, Molecular and Cellular Endocrinology.

Regulation of c-fos, c-jun and jun-B messenger ribonucleic acids by angiotensin-II and corticotropin in ovine and bovine adrenocortical cells.

S. Hall, C. Jaillard, J. Saez, 1992, Endocrinology.

Immunohistochemical localization of transforming growth factor β1 and β2 in the fetal and neonatal rat ovary

R. Habert, J. Saez, C. Levacher, 1996 .

Transforming growth factor beta treatment decreases ACTH receptors on ovine adrenocortical cells.

W. Rainey, J. Saez, I. Viard, 1989, The Journal of biological chemistry.

Mediators of the effects of ACTH on adrenal cells.

A. Morera, J. Saez, A. Dazord, 1981, Advances in cyclic nucleotide research.

[ACTH receptors].

P. Durand, J. Saez, M. Bégeot, 1989, Annales d'endocrinologie.

Variations in guanine-binding proteins (Gs, Gi) in cultured bovine adrenal cells. Consequences on the effects of phorbol ester and angiotensin II on adrenocorticotropin-induced and cholera-toxin-induced cAMP production.

A. Penhoat, J. Saez, M. Bégeot, 1988, European journal of biochemistry.

Synergistic effects of corticotropin and insulin-like growth factor I on corticotropin receptors and corticotropin responsiveness in cultured bovine adrenocortical cells.

A. Penhoat, C. Jaillard, J. Saez, 1989, Biochemical and biophysical research communications.

Angiotensin Ii Receptor Subtypes At1 and At2 Are Down-regulated by Angiotensin Ii through At1 Receptor by Different Mechanisms*

J. Saez, M. Bégeot, M. Berthelon, 2022 .

Regulation by adrenocorticotropin (ACTH), angiotensin II, transforming growth factor-beta, and insulin-like growth factor I of bovine adrenal cell steroidogenic capacity and expression of ACTH receptor, steroidogenic acute regulatory protein, cytochrome P450c17, and 3beta-hydroxysteroid dehydrogenas

C. Le Roy, D. Stocco, J. Y. Li, 2000, Endocrinology.

hCG-induced prostaglandin E2 and F2 alpha release in adult rat testis: role in Leydig cell desensitization to hCG.

F. Dray, F. Haour, J. Saez, 1979, Life Science.

Expression and regulation of Gαq and Gαll mRNAs and proteins in bovine adrenal cells

J. Saez, A. Derrien, D. Langlois, 1996, Molecular and Cellular Endocrinology.

ACTH AND PROSTAGLANDINS, RECEPTORS IN HUMAN ADRENOCORTICAL TUMORS

J. Saez, A. Dazord, L. Audi, 1975, Pediatric Research.

Autocrine Role of TGFβ1 in Adrenal

C. Le Roy, C. Roy, A. Penhoat, 1998, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

Stimulatory effect of insulin and insulin-like growth factor I on Gi proteins and angiotensin-II-induced phosphoinositide breakdown in cultured bovine adrenal cells.

K. Hinsch, J. Saez, M. Bégeot, 1990, Endocrinology.

Gonadotropin receptor complexes and free receptors in porcine Leydig cell cultures during recovery from hCG stimulation.

P. Leduque, F. Haour, P. Dubois, 1984, Biochemical and Biophysical Research Communications - BBRC.

Effects of angiotensin-II on inositol phosphate accumulation and calcium influx in bovine adrenal and Y-1 tumor adrenal cells.

J. Saez, M. Bégeot, D. Langlois, 1990, Endocrine research.

Interactions of adrenocorticotropic hormone with its adrenal receptors. Degradation of ACTH-1-24 and ACTH-11-24.

A. Morera, J. Saez, A. Dazord, 1975, The Journal of biological chemistry.

Opposite effects of ACTH and glucocorticoids on adrenal DNA synthesis in vivo.

A. Morera, J. Saez, D. Gallet, 1977, Endocrinology.

Adrenal growth factors in the rat mammotropic pituitary tumor (MtT-F4).

A. Cathiard, J. Saez, 1981, Biochemical and biophysical research communications.

Mechanisms implicated in ACTH-induced steroidogenic and DNA synthesis refractoriness on adrenal mouse cell line (Y-1).

A. Morera, J. Saez, 1980, Journal of steroid biochemistry.

Leydig cell and extracellular matrix effects on Sertoli cell function: biochemical and morphologic studies.

P. Chatelain, J. Reventós, J. Saez, 1989, Journal of andrology.

Transforming growth factor β3 in the fetal and neonatal rat testis: immunolocalization and effect on fetal Leydig cell function

R. Habert, C. Pairault, R. Olaso, 1999, Histochemistry and Cell Biology.

ACTH-induced refractoriness in cultured adrenal cell line (Y1).

A. Morera, A. Cathiard, J. Saez, 1978, Biochemical and biophysical research communications.

ACTH in vivo stimulation of the synthesis of a specific mitochondrial protein in the rat.

J. Saez, A. Dazord, D. Gallet de Santerre, 1981, Biochemical and biophysical research communications.

hCG-Increased phosphorylation of proteins in primary culture of Leydig cells: further characterization.

F. Haour, J. Saez, A. Dazord, 1984, Biochemical and biophysical research communications.

hCG increased phosphorylation of proteins in primary cultures of porcine Leydig cells.

M. Benahmed, A. González‐Martínez, F. Haour, 1982, Biochemical and biophysical research communications.

Acth Effects on Steroidogenesis and Adrenal Protein Synthesis: Relation Structure-Function

J. Saez, A. Dazord, 1982 .

Corticotropin regulation of the synthesis of a specific rat adrenal cytosolic protein. Effects of hypophysectomy and actinomycin D.

J. Saez, A. Dazord, H. Cohen, 1979, The Biochemical journal.

Effect of corticotropin treatment in vivo on the synthesis of a specific adrenal cytosolic protein. Characterization by dual-labelling technique and polyacrylamide-gel electrophoresis.

J. Saez, A. Dazord, D. Gallet, 1978, The Biochemical journal.

Development and function of the human fetal adrenal cortex.

J. Y. Li, J. Saez, D. Langlois, 2002, Journal of pediatric endocrinology & metabolism : JPEM.

Expression and effect of insulin-like growth factor I on rat fetal Leydig cell function and differentiation.

V. Rouiller-Fabre, R. Habert, J. Saez, 1998, Endocrinology.

Inhibition of ACTH responsiveness of adrenocortical and fat cells adenylate cyclase by 4-methyl-4-aza-5 alpha-cholestane.

R. Sharma, J. Saez, G. Tell, 1980, Journal of steroid biochemistry.

Opposite vectorial secretion of insulin-like growth factor I and its binding proteins by pig Sertoli cells cultured in the bicameral chamber system.

J. Saez, M. Vigier, O. Avallet, 1992, Endocrinology.

Identification and characterization of angiotensin-II receptor subtypes in cultured bovine and human adrenal fasciculata cells and PC12W cells.

M. Lebrethon, J. Saez, R. Ouali, 1993, Endocrinology.

Transcriptional and Translational Regulation of Angiotensin II Type 2 Receptor by Angiotensin II and Growth Factors1.

J. Saez, M. Berthelon, D. Langlois, 1999, Endocrinology.

Vasopressin induces breakdown of phosphoinositides in adrenal tumor Y-1 cells without a steroidogenic effect

J. Saez, M. Bégeot, D. Langlois, 1988, Molecular and Cellular Endocrinology.

Leydig cells: endocrine, paracrine, and autocrine regulation.

J. Saez, 1994, Endocrine reviews.

Biochemical modifications involved in the maturation of the ovine fetal adrenal gland in late gestation: their modalities and regulation.

A. Locatelli, P. Durand, A. Cathiard, 1985, Reproduction, nutrition, developpement.

Guanosine triphosphate-sensitive adenylate cyclase of adrenocorticotrophic hormone- and prostaglandin-resistant human adrenocortical tumors.

A. Cathiard, J. Saez, G. Tell, 1978, Cancer research.

Adenyl Cyclase Activity in Rat, Ovine and Human Adrenal Preparations

J. Saez, A. Dazord, D. Gallet, 1975 .

Inhibition of RNA and DNA synthesis in Sertoli cells by co-culture with spermatogenic cells.

M. Rivarola, J. Saez, P. Sanchez, 1986, International journal of andrology.

Effects of FSH on acidic nuclear protein synthesis in cultured pig Sertoli cells

M. Perrard, J. Saez, A. Dazord, 1984, FEBS letters.

Food-dependent Cushing's syndrome: characterization and functional role of gastric inhibitory polypeptide receptor in the adrenals of three patients.

T. Usdin, Y. Reznik, G. Narboni, 1998, The Journal of clinical endocrinology and metabolism.

Paracrine role of Sertoli cells.

E. Tabone, M. Rivarola, J. Saez, 1986, Medical biology.