Brian Mcauliffe

发表

Increased sensitivity of HIV variants selected by attachment inhibitors to broadly neutralizing antibodies.

L. Alexander, M. Krystal, R. Colonno, 2010, Virology.

Envelope Conformational Changes Induced by Human Immunodeficiency Virus Type 1 Attachment Inhibitors Prevent CD4 Binding and Downstream Entry Events

James E. Robinson, R. Colonno, P. Clapham, 2006, Journal of Virology.

Homology models of the HIV-1 attachment inhibitor BMS-626529 bound to gp120 suggest a unique mechanism of action

N. Meanwell, D. Langley, M. Krystal, 2014, Proteins.

Genotypic correlates of susceptibility to HIV-1 attachment inhibitor BMS-626529, the active agent of the prodrug BMS-663068.

D. Langley, M. Krystal, N. Ray, 2014, The Journal of antimicrobial chemotherapy.

Scaffold modifications to the 4-(4,4-dimethylpiperidinyl) 2,6-dimethylpyridinyl class of HIV-1 allosteric integrase inhibitors.

K. Kish, N. Meanwell, M. Krystal, 2022, Bioorganic & medicinal chemistry.

Discovery and Preclinical Profiling of GSK3839919, a Potent HIV-1 Allosteric Integrase Inhibitor.

K. Kish, N. Meanwell, C. Cianci, 2022, ACS medicinal chemistry letters.

Application of Cassette Ultracentrifugation Using Non-labeled Compounds and Liquid Chromatography-Tandem Mass Spectrometry Analysis for High-Throughput Protein Binding Determination.

D. Drexler, C. Cianci, Jun Zhang, 2016, Journal of pharmaceutical sciences.

Inhibition of Envelope-Mediated CD4 (cid:1) -T-Cell Depletion by Human Immunodeﬁciency Virus Attachment Inhibitors (cid:1)

L. Alexander, J. Kadow, M. Agler, 2009 .

Inhibitors of human immunodeficiency virus type 1 (HIV-1) attachment. 5. An evolution from indole to azaindoles leading to the discovery of 1-(4-benzoylpiperazin-1-yl)-2-(4,7-dimethoxy-1H-pyrrolo[2,3-c]pyridin-3-yl)ethane-1,2-dione (BMS-488043), a drug candidate that demonstrates antiviral activity

N. Meanwell, R. Colonno, J. Kadow, 2009, Journal of medicinal chemistry.

5,6,7,8-Tetrahydro-1,6-naphthyridine Derivatives as Potent HIV-1-Integrase-Allosteric-Site Inhibitors.

Barry L. Johnson, K. Kish, N. Meanwell, 2019, Journal of medicinal chemistry.

Design, Synthesis and SAR Study of Novel C2-Pyrazolopyrimidine Amides and Amide Isosteres as Allosteric Integrase Inhibitors.

N. Meanwell, C. Cianci, M. Krystal, 2020, Bioorganic & medicinal chemistry letters.

Inhibition of influenza virus replication via small molecules that induce the formation of higher-order nucleoprotein oligomers

Eric T Baldwin, Samuel W Gerritz, Michael Sinz, 2011, Proceedings of the National Academy of Sciences.

Biochemical and Genetic Characterizations of a Novel Human Immunodeficiency Virus Type 1 Inhibitor That Blocks gp120-CD4 Interactions

N. Meanwell, D. Langley, R. Colonno, 2003, Journal of Virology.

In Vitro Antiviral Characteristics of HIV-1 Attachment Inhibitor BMS-626529, the Active Component of the Prodrug BMS-663068

N. Meanwell, M. Krystal, J. Kadow, 2012, Antimicrobial Agents and Chemotherapy.

GSK3640254 Is a Novel HIV-1 Maturation Inhibitor with an Optimized Virology Profile

N. Meanwell, Zeyu Lin, Joseph L. Cantone, 2021, Antimicrobial Agents and Chemotherapy.

Structure-based amelioration of PXR transactivation in a novel series of macrocyclic allosteric inhibitors of HIV-1 integrase.

Stephen R. Johnson, N. Meanwell, D. Langley, 2020, Bioorganic & medicinal chemistry letters.

Design, Synthesis, and Preclinical Profiling of GSK3739936 (BMS-986180), an Allosteric Inhibitor of HIV-1 Integrase with Broad-Spectrum Activity toward 124/125 Polymorphs.

K. Kish, N. Meanwell, H. Lewis, 2022, Journal of medicinal chemistry.

Inhibition of Envelope-Mediated CD4+-T-Cell Depletion by Human Immunodeficiency Virus Attachment Inhibitors

L. Alexander, J. Kadow, Tao Wang, 2009, Antimicrobial Agents and Chemotherapy.

Genotypic correlates of susceptibility to HIV-1 attachment inhibitor BMS-626529, the active agent of the prodrug BMS-663068.

D. Langley, M. Krystal, N. Ray, 2014, The Journal of antimicrobial chemotherapy.