Dominik Lock

发表

Titratable Pharmacological Regulation of CAR T Cells Using Zinc Finger-Based Transcription Factors

S. Ludwig, J. Mittelstaet, C. Rossig, 2021, Cancers.

Novel adapter CAR-T cell technology for precisely controllable multiplex cancer targeting

G. Bender, B. Pichler, S. Miltenyi, 2020, Oncoimmunology.

Anti-CD19 CARs displayed at the surface of lentiviral vector particles promote transduction of target-expressing cells

T. Cathomen, C. Rossig, F. Blaeschke, 2021, Molecular therapy. Methods & clinical development.

Automated, scaled, transposon-based production of CAR T cells

M. Eyrich, M. Schmeer, M. Schleef, 2022, Journal for ImmunoTherapy of Cancer.

Joining Forces for Cancer Treatment: From “TCR versus CAR” to “TCR and CAR”

C. Evaristo, A. Künkele, Dominik Lock, 2022, International journal of molecular sciences.

Automated Manufacturing of Potent CD20-Directed Chimeric Antigen Receptor T Cells for Clinical Use.

U. Holtick, P. Borchmann, O. Hardt, 2017, Human gene therapy.

Identification of CD318, TSPAN8 and CD66c as target candidates for CAR T cell based immunotherapy of pancreatic adenocarcinoma

A. Bosio, J. Schüler, D. Eckardt, 2021, Nature Communications.

FAS-Based Cell Depletion Facilitates the Selective Isolation of Mouse Induced Pluripotent Stem Cells

A. Schambach, A. Bosio, D. Wedekind, 2014, PloS one.

Combined targeting of soluble latent TGF-ß and a solid tumor-associated antigen with adapter CAR T cells

M. Mallmann, M. von Bergwelt-Baildon, J. Mittelstaet, 2022, Oncoimmunology.

CD137+CD154− Expression As a Regulatory T Cell (Treg)-Specific Activation Signature for Identification and Sorting of Stable Human Tregs from In Vitro Expansion Cultures

Jörn Walter, Pascal Giehr, Andrew Kaiser, 2018, Front. Immunol..

Automated generation of gene-edited CAR T cells at clinical scale

T. Cathomen, C. Mussolino, S. Wild, 2020, Molecular therapy. Methods & clinical development.

Targeting Stage-Specific Embryonic Antigen 4 (SSEA-4) in Triple Negative Breast Cancer by CAR T Cells Results in Unexpected on Target/off Tumor Toxicities in Mice

A. Bosio, D. Eckardt, O. Hardt, 2023, International journal of molecular sciences.

653. Sialyl Glycolipid Stage-Specific Embryonic Antigen 4 (SSEA4) - A Novel Target for CAR T Cell Therapy of Solid Cancers

A. Bosio, O. Hardt, A. Aloia, 2016 .

Automated manufacture of ΔNPM1 TCR-engineered T cells for AML therapy

M. Griffioen, Dominik Lock, C. Hoogstraten, 2024, Molecular therapy. Methods & clinical development.