K. James

发表

The discovery of long acting β2-adrenoreceptor agonists

Alan Daniel Brown, Mark E. Bunnage, M. Bunnage, 2007 .

Inhalation by design: dual pharmacology β-2 agonists/M3 antagonists for the treatment of COPD.

M. Bunnage, David A. Price, M. Trevethick, 2011, Bioorganic & medicinal chemistry letters.

Optimized glucuronidation of dual pharmacology β-2 agonists/M3 antagonists for the treatment of COPD

M. Bunnage, David A. Price, M. Trevethick, 2011 .

Molecular hybridization yields triazole bronchodilators for the treatment of COPD.

M. Trevethick, E. Stuart, P. Glossop, 2015, Bioorganic & medicinal chemistry letters.

Transannular reactions of 5-hydroxylamino and 5-azido dibenzo[a,e]cyclo-octatrienes: regiospecific syntheses of dibenzohomotropane and pavine analogues

P. Leeson, R. Baker, K. James, 1989 .

The design and synthesis of a novel series of indole derived selective ETA antagonists

K. Dack, K. James, R. Dickinson, 2002 .

Inhalation by design: novel tertiary amine muscarinic M₃ receptor antagonists with slow off-rate binding kinetics for inhaled once-daily treatment of chronic obstructive pulmonary disease.

M. Bunnage, David A. Price, A. Wood, 2011, Journal of medicinal chemistry.

Succinyl hydroxamates as potent and selective non-peptidic inhibitors of procollagen C-proteinase: design, synthesis, and evaluation as topically applied, dermal anti-scarring agents.

P. Fish, S. Bailey, James E. J. Mills, 2008, Bioorganic & medicinal chemistry letters.

Selective fluorination of 1-hydroxyisoquinolines using Selectfluor™

David A. Price, S. Osborne, G. Harbottle, 2007 .

Development of a Scaleable Synthesis of a Geminal Dimethyl Tertiary Amine as an Inhaled Muscarinic Antagonist for the Treatment of COPD

D. Entwistle, P. Glossop, Barry. R. Dillon, 2012 .

Inhalation by design: novel ultra-long-acting β(2)-adrenoreceptor agonists for inhaled once-daily treatment of asthma and chronic obstructive pulmonary disease that utilize a sulfonamide agonist headgroup.

M. Bunnage, David A. Price, A. Brown, 2010, Journal of medicinal chemistry.

The discovery of adamantyl-derived, inhaled, long acting beta(2)-adrenoreceptor agonists.

Mark E Bunnage, M. Bunnage, David A. Price, 2008, Bioorganic & medicinal chemistry letters.

Discovery of Potent, Selective, and Peripherally Restricted Pan-Trk Kinase Inhibitors for the Treatment of Pain.

Gareth J Waldron, R. Grimley, M. Andrews, 2018, Journal of medicinal chemistry.

Potent and selective nonpeptidic inhibitors of procollagen C-proteinase.

Julian Blagg, P. Fish, R. Butt, 2007, Journal of medicinal chemistry.

Role of hydrogen bonding in ligand interaction with the N-methyl-D-aspartate receptor ion channel.

E. Wong, P. Leeson, R. Carling, 1990, Journal of Medicinal Chemistry.