C. Lane

发表

The discovery of long acting β2-adrenoreceptor agonists

Alan Daniel Brown, Mark E. Bunnage, M. Bunnage, 2007 .

Discovery and Optimization of Selective Nav1.8 Modulator Series That Demonstrate Efficacy in Preclinical Models of Pain.

Tanya L Hay, E. Stevens, P. Bungay, 2015, ACS medicinal chemistry letters.

A novel series of potent and selective PDE5 inhibitors with potential for high and dose-independent oral bioavailability.

K. Beaumont, N. Mount, David G. Brown, 2006, Journal of medicinal chemistry.

Combined Directed ortho Metalation - Grubbs Metathesis Tactics. Synthesis of Benzazepine, Benzazocine, and Benzannulated 7-, 8-, 9-, and 15-Membered Ring Sulfonamide Heterocycles

V. Snieckus, C. Lane, 2000 .

Inhalation by design: novel ultra-long-acting β(2)-adrenoreceptor agonists for inhaled once-daily treatment of asthma and chronic obstructive pulmonary disease that utilize a sulfonamide agonist headgroup.

M. Bunnage, David A. Price, A. Brown, 2010, Journal of medicinal chemistry.

The discovery of UK-369003, a novel PDE5 inhibitor with the potential for oral bioavailability and dose-proportional pharmacokinetics.

M. Bunnage, K. Beaumont, D. Leahy, 2012, Bioorganic & medicinal chemistry.

Small molecule inhibitors of IgE synthesis.

A. Brown, M. Lansdell, G. Maw, 2006, Bioorganic & medicinal chemistry letters.

The discovery of adamantyl-derived, inhaled, long acting beta(2)-adrenoreceptor agonists.

Mark E Bunnage, M. Bunnage, David A. Price, 2008, Bioorganic & medicinal chemistry letters.

The discovery of indole-derived long acting beta2-adrenoceptor agonists for the treatment of asthma and COPD.

Mark E Bunnage, M. Bunnage, David A. Price, 2007, Bioorganic & medicinal chemistry letters.

Challenges of drug discovery in novel target space. The discovery and evaluation of PF-3893787: a novel histamine H4 receptor antagonist.

C. Mowbray, N. Swain, A. Bell, 2011, Bioorganic & medicinal chemistry letters.