Andrew Brearley

A physical properties based approach for the exploration of a 4-hydroxybenzothiazolone series of beta2-adrenoceptor agonists as inhaled long-acting bronchodilators.

B. Cuenoud, R. Taylor, S. Charlton, 2010, Bioorganic & medicinal chemistry letters.

Efficient and facile synthesis of acrylamide libraries for protein-guided tethering.

C. E. Allen, A. Armstrong, N. Press, 2015, Organic letters.

Synthesis and evaluation of two series of 4'-aza-carbocyclic nucleosides as adenosine A2A receptor agonists.

J. Fozard, S. Charlton, P. Gedeck, 2010, Bioorganic & medicinal chemistry letters.

Structural basis of SARM1 activation, substrate recognition, and inhibition by small molecules.

J. Milbrandt, B. Kobe, P. Kerry, 2022, Molecular cell.

Pharmacological SARM1 inhibition protects axon structure and function in paclitaxel-induced peripheral neuropathy

T. Engber, S. Boyce, K. Danker, 2021, Brain : a journal of neurology.

The identification of 7-[(R)-2-((1S,2S)-2-benzyloxycyclopentylamino)-1-hydroxyethyl]-4-hydroxybenzothiazolone as an inhaled long-acting β2-adrenoceptor agonist.

J. Fozard, S. Charlton, M. Gosling, 2014, Bioorganic & medicinal chemistry letters.