Jiong Zhao

发表

Mutation of the retinoblastoma tumor suppressor gene sensitizes cancers to mitotic inhibitor induced cell death.

W. Du, Zhenyu Zhang, Y. Liao, 2014, American journal of cancer research.

Original Article Mutation of the retinoblastoma tumor suppressor gene sensitizes cancers to mitotic inhibitor induced cell death

W. Du, Zhenyu Zhang, Y. Liao, 2014 .

G1T48, an oral selective estrogen receptor degrader, and the CDK4/6 inhibitor lerociclib inhibit tumor growth in animal models of endocrine-resistant breast cancer

G. Thatcher, J. Bisi, J. Strum, 2020, Breast Cancer Research and Treatment.

Ginsenoside Rh2 induces apoptosis and paraptosis-like cell death in colorectal cancer cells through activation of p53.

T. He, Chong-Zhi Wang, C. Yuan, 2011, Cancer letters.

Design and Synthesis of Basic Selective Estrogen Receptor Degraders for Endocrine Therapy Resistant Breast Cancer

Hu Chen, D. Tonetti, Huiping Zhao, 2020 .

Selective Human Estrogen Receptor Partial Agonists (ShERPAs) for Tamoxifen-Resistant Breast Cancer.

J. Katzenellenbogen, G. Thatcher, D. Tonetti, 2016, Journal of medicinal chemistry.

XP-524 is a dual-BET/EP300 inhibitor that represses oncogenic KRAS and potentiates immune checkpoint inhibition in pancreatic cancer

A. Rana, K. Ratia, J. Trevino, 2022, Proceedings of the National Academy of Sciences.

Novel pyrrolopyridone bromodomain and extra-terminal motif (BET) inhibitors effective in endocrine-resistant ER+ breast cancer with acquired resistance to fulvestrant and palbociclib.

G. Thatcher, K. Ratia, D. Tonetti, 2020, Journal of medicinal chemistry.

Novel Selective Estrogen Receptor Downregulators (SERDs) Developed against Treatment-Resistant Breast Cancer.

G. Thatcher, D. Tonetti, Huiping Zhao, 2017, Journal of medicinal chemistry.

Deregulated G1–S control and energy stress contribute to the synthetic-lethal interactions between inactivation of RB and TSC1 or TSC2

W. Du, Tianyi Zhang, Jiong Zhao, 2013, Journal of Cell Science.

Design and Synthesis of Basic Selective Estrogen Receptor Degraders (B-SERDs) for Endocrine Therapy Resistant Breast Cancer.

Hu Chen, G. Thatcher, D. Tonetti, 2019, Journal of medicinal chemistry.

Structure-Guided Design and Synthesis of Pyridinone-Based Selective Bromodomain and Extra-Terminal Domain (BET)-First Bromodomain (BD1) Inhibitors.

K. Ratia, Jiong Zhao, Yangfeng Li, 2024, Journal of medicinal chemistry.