T. Kirchberger

发表

Aberrant Cyclization Affords a C-6 Modified Cyclic Adenosine 5′-Diphosphoribose Analogue with Biological Activity in Jurkat T Cells

B. Potter, Mark P Thomas, A. Guse, 2012, Journal of medicinal chemistry.

Trifluoromethylated cyclic-ADP-ribose mimic: synthesis of 8-trifluoromethyl-N(1)-[(5''-O-phosphorylethoxy)methyl]-5'-O-phosphorylinosine-5',5''-cyclic pyrophosphate (8-CF(3)-cIDPRE) and its calcium release activity in T cells.

Zhenjun Yang, A. Guse, T. Kirchberger, 2010, Organic & biomolecular chemistry.

Ins(1,4,5)P3 3-kinase-A overexpression induces cytoskeletal reorganization via a kinase-independent mechanism.

C. Elling, G. Mayr, M. Nalaskowski, 2008, The Biochemical journal.

NAADP Mobilizes Calcium from the Endoplasmic Reticular Ca2+ Store in T-lymphocytes*

A. Guse, T. Kirchberger, M. Steen, 2007, Journal of Biological Chemistry.

Running Head: 2ʹ-Deoxy-ADPR is an endogenous superagonist of TRPM2

A. Guse, M. Flato, Christelle Moreau, 2017 .

Structure–Activity Relationship of Adenosine 5′-diphosphoribose at the Transient Receptor Potential Melastatin 2 (TRPM2) Channel: Rational Design of Antagonists

B. Potter, A. Guse, Christelle Moreau, 2013, Journal of medicinal chemistry.

2'-Deoxyadenosine 5'-diphosphoribose is an endogenous TRPM2 superagonist.

B. Potter, A. Guse, M. Flato, 2017, Nature chemical biology.

NAADP-mediated Ca2+ signaling via type 1 ryanodine receptor in T cells revealed by a synthetic NAADP antagonist

M. Hohenegger, B. Potter, A. Flügel, 2009, Proceedings of the National Academy of Sciences.

Ligand-induced activation of human TRPM2 requires the terminal ribose of ADPR and involves Arg1433 and Tyr1349

B. Potter, Mark P Thomas, A. Guse, 2017, The Biochemical journal.

8-Bromo-cyclic inosine diphosphoribose: towards a selective cyclic ADP-ribose agonist

B. Potter, A. Flügel, F. Odoardi, 2009, The Biochemical journal.

Cellular effects and metabolic stability of N1‐cyclic inosine diphosphoribose and its derivatives

B. Potter, A. Flügel, C. Cordiglieri, 2006, British journal of pharmacology.

Measuring CD38 (ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase) activity by reverse-phase HPLC.

A. Guse, T. Kirchberger, 2013, Cold Spring Harbor protocols.