T. Ohnuma

H. Arai, N. Shibata, T. Ohnuma, 2015, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

No association between glutathione‐synthesis‐related genes and Japanese schizophrenia

H. Baba, H. Arai, N. Shibata, 2011, Psychiatry and clinical neurosciences.

Significance of NMDA receptor-related glutamatergic amino acid levels in peripheral blood of patients with schizophrenia

H. Arai, T. Ohnuma, 2011, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

A magnetic resonance imaging study in first‐episode disorganized‐type patients with schizophrenia

H. Arai, M. Kimura, M Kimura, 1997, Psychiatry and clinical neurosciences.

Haloperidol plasma concentration in Japanese psychiatric subjects with gene duplication of CYP2D6.

H. Arai, N. Shibata, T. Ohnuma, 2003, British journal of clinical pharmacology.

Genetic Association between Ghrelin Polymorphisms and Alzheimer’s Disease in a Japanese Population

H. Arai, N. Shibata, T. Ohnuma, 2011, Dementia and Geriatric Cognitive Disorders.

Genetic association between APOA1 and APOD polymorphisms and Alzheimer’s disease in a Japanese population

Shunichiro Shinagawa, Hisashi Yamada, H. Arai, 2013, Journal of Neural Transmission.

No genetic association between alpha-2 macroglobulin I1000V polymorphism and Japanese sporadic Alzheimer's disease

H. Arai, A. Ueki, N. Shibata, 2000, Neuroscience Letters.

No genetic association between SLC7A10 and Japanese patients with schizophrenia

H. Baba, H. Arai, N. Shibata, 2011, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

Functional genetic variation at the NRGN gene and schizophrenia: Evidence from a gene‐based case–control study and gene expression analysis

H. Kazui, M. Ikeda, K. Ohi, 2012, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

Genetic or Psychogenic? A Case Study of “Folie à Quatre” Including Twins

H. Arai, T. Ohnuma, 2015, Case reports in psychiatry.

Effect of Aging on Gene Expression of Metabotropic Glutamate Receptor 5 and Glutamate Transporter‐1 in the Prefrontal Cortex of Schizophrenics

P. Emson, T. Ohnuma, H. Shimada, 2001 .

Association between DNA Methylation of the BDNF Promoter Region and Clinical Presentation in Alzheimer's Disease

Hisashi Yamada, Kazuhiro Kondo, Tohru Ohnuma, 2015, Dementia and Geriatric Cognitive Disorders Extra.

Erratum to: Genetic Association Between KIBRA Polymorphism and Alzheimer’s Disease with in a Japanese Population

K. Tagai, Shunichiro Shinagawa, Hisashi Yamada, 2015, NeuroMolecular Medicine.

Genome-Wide Association Study Detected Novel Susceptibility Genes for Schizophrenia and Shared Trans-Populations/Diseases Genetic Effect.

Y. Kamatani, N. Kanahara, M. Kubo, 2018, Schizophrenia bulletin.

Genetic association between Notch4 polymorphisms and Alzheimer's disease in the Japanese population.

Tomoko Watanabe, H. Arai, A. Ueki, 2007, The journals of gerontology. Series A, Biological sciences and medical sciences.

Genetic Association Between KIBRA Polymorphism and Alzheimer’s Disease with in a Japanese Population

Shunichiro Shinagawa, Hisashi Yamada, H. Arai, 2015, NeuroMolecular Medicine.

Genetic association between CALHM1, 2, and 3 polymorphisms and Alzheimer's disease in a Japanese population.

H. Baba, H. Arai, N. Shibata, 2010, Journal of Alzheimer's disease : JAD.

Association of copy number polymorphisms at the promoter and translated region of COMT with Japanese patients with schizophrenia

M. Ikeda, R. Hashimoto, H. Yamamori, 2016, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

Genomewide high-density SNP linkage analysis of 236 Japanese families supports the existence of schizophrenia susceptibility loci on chromosomes 1p, 14q, and 20p.

Naoshi Kaneko, Hiroki Shibata, Takashi Asada, 2005, American journal of human genetics.

Significance of measurements of peripheral carbonyl stress markers in a cross-sectional and longitudinal study in patients with acute-stage schizophrenia.

H. Arai, N. Shibata, T. Ohnuma, 2014, Schizophrenia bulletin.

Plasma Concentration of Risperidone Showed a Correlation with Daily Dose, but not with Age nor Cytochrome P‐450 2D6 Gene Polymorphisms in Japanese Schizophrenics

H. Arai, N. Shibata, Tadashi C. Takahashi, 2002 .

Carbonyl Stress and Microinflammation-Related Molecules as Potential Biomarkers in Schizophrenia

H. Arai, T. Ohnuma, Narimasa Katsuta, 2018, Front. Psychiatry.

Use of skin advanced glycation end product levels measured using a simple noninvasive method as a biological marker for the diagnosis of neuropsychiatric diseases

T. Ohnuma, Hitoki Hirose, Ken Nakayama, 2020, International journal of methods in psychiatric research.

Expression of the human excitatory amino acid transporter 2 and metabotropic glutamate receptors 3 and 5 in the prefrontal cortex from normal individuals and patients with schizophrenia.

P. McKenna, S. Augood, P. Emson, 1998, Brain research. Molecular brain research.

Effect of IL-6 polymorphism on risk of Alzheimer disease: genotype-phenotype association study in Japanese cases.

H. Baba, H. Arai, A. Ueki, 2002, American journal of medical genetics.

Lack of an association of estrogen receptor alpha gene polymorphisms and transcriptional activity with Alzheimer disease.

P. Emson, C. Harrington, H. Arai, 2000, Archives of neurology.

Clinical Interventions in Aging Dovepress

H. Arai, N. Shibata, T. Ota, 2022 .

Genetic association between USF 1 and USF 2 gene polymorphisms and Japanese Alzheimer's disease.

Tomoko Watanabe, H. Arai, A. Ueki, 2006, The journals of gerontology. Series A, Biological sciences and medical sciences.

No genetic association between the SLC1A2 gene and Japanese patients with schizophrenia

H. Baba, H. Arai, N. Shibata, 2009, Neuroscience Letters.

Genetic analysis of the TrkB gene and schizophrenia in the Japanese population: Juntendo University Schizophrenia Projects (JUSP)

H. Arai, N. Shibata, T. Ohnuma, 2007, Neuroscience Letters.

Requirement of tryptophan hydroxylase during development for maturation of sensorimotor gating.

H. Arai, H. Nishimura, Y. Koyama, 2006, Journal of molecular biology.

Association study of the G72 gene with schizophrenia in a Japanese population: A multicenter study

T. Kudo, H. Kazui, M. Ikeda, 2009, Schizophrenia Research.

Association study between Disrupted-in-Schizophrenia-1 (DISC1) and Japanese patients with treatment-resistant schizophrenia (TRS)

H. Baba, H. Arai, Toshihito Suzuki, 2011, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

The Relationship Between the Response of Clinical Symptoms and Plasma Olanzapine Concentration, Based on Pharmacogenetics: Juntendo University Schizophrenia Projects (JUSP)

H. Arai, N. Shibata, T. Ohnuma, 2008, Therapeutic drug monitoring.

Genetic evidence for association between NOTCH4 and schizophrenia supported by a GWAS follow-up study in a Japanese population

K. Matsuo, E. Hattori, M. Ikeda, 2013, Molecular Psychiatry.

No genetic association between polymorphisms in the Fyn kinase gene and age of schizophrenic onset

H. Arai, N. Shibata, M. Yamashina, 2003, Neuroscience Letters.

Hypothesis: Minimal changes in neural transmission in schizophrenia: Decreased glutamatergic and GABAergic functions in the prefrontal cortex

H. Arai, Toshihito Suzuki, T. Ohnuma, 2005, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

Gene expression of metabotropic glutamate receptor 5 and excitatory amino acid transporter 2 in the schizophrenic hippocampus.

P. McKenna, P. Emson, R. Faull, 2000, Brain research. Molecular brain research.

Pathophysiology of Patients with Schizophrenia: Genetic and Environmental Factors

H. Arai, T. Ohnuma, 2017 .

Altered serum glyceraldehyde-derived advanced glycation end product (AGE) and soluble AGE receptor levels indicate carbonyl stress in patients with schizophrenia

Yusuke Suzuki, Y. Tomino, H. Arai, 2015, Neuroscience Letters.

Expression of Fyn, a non-receptor tyrosine kinase in prefrontal cortex from patients with schizophrenia and its correlation with clinical onset.

P. McKenna, P. Emson, H. Arai, 2003, Brain research. Molecular brain research.

No associations found between the genes situated at 6p22.1, HIST1H2BJ, PRSS16, and PGBD1 in Japanese patients diagnosed with schizophrenia

M. Ikeda, K. Ohi, R. Hashimoto, 2012, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

Measurement of GABAergic parameters in the prefrontal cortex in schizophrenia: focus on GABA content, GABAA receptor α-1 subunit messenger RNA and human GABA transporter-1 (hGAT-1) messenger RNA expression

P. McKenna, S. Augood, P. Emson, 1999, Neuroscience.

Medium‐chain triglycerides given in the early stage of mild‐to‐moderate Alzheimer's disease enhance memory function

H. Arai, N. Shibata, T. Ota, 2017, Psychogeriatrics.

Juntendo Medical Journal

T. Ohnuma, 2020 .

The possibility that requiring high-dose olanzapine cannot be explained by pharmacokinetics in the treatment of acute-phase schizophrenia

Y. Sudo, H. Takebayashi, C. Usui, 2013, Psychiatry Research.

Gene expression of PSD95 in prefrontal cortex and hippocampus in schizophrenia

P. McKenna, P. Emson, R. Faull, 2000, Neuroreport.

Genetic association between RAGE polymorphisms and Alzheimer's disease and Lewy body dementias in a Japanese cohort: a case–control study

N. Hattori, Shunichiro Shinagawa, Hisashi Yamada, 2017, International journal of geriatric psychiatry.

Association analysis between functional polymorphism of the rs4606 SNP in the RGS2 gene and antipsychotic-induced Parkinsonism in Japanese patients with schizophrenia: Results from the Juntendo University Schizophrenia Projects (JUSP)

H. Arai, Toshihito Suzuki, N. Shibata, 2010, Neuroscience Letters.

An Association Study Between Educational Attainment-Related Genes and Cognitive Functions in Japanese Patients with Schizophrenia

H. Arai, T. Ohnuma, Eriko Tani, 2019, Juntendo Medical Journal.

Usefulness of DNA Methylation Levels in COASY and SPINT1 Gene Promoter Regions as Biomarkers in Diagnosis of Alzheimer’s Disease and Amnestic Mild Cognitive Impairment

Shunichiro Shinagawa, Hisashi Yamada, H. Arai, 2016, PloS one.

Development of Biomarkers Based on DNA Methylation in the NCAPH2/LMF2 Promoter Region for Diagnosis of Alzheimer’s Disease and Amnesic Mild Cognitive Impairment

Shunichiro Shinagawa, Hisashi Yamada, H. Arai, 2016, PloS one.

Genetic Association Between CALHM1, 2 and 3 Polymorphisms and Alzheimer’s Disease in a Japanese Population

H. Baba, H. Arai, N. Shibata, 2011, Alzheimer's & Dementia.

No Correlation between Plasma NMDA-Related Glutamatergic Amino Acid Levels and Cognitive Function in Medicated Patients with Schizophrenia

H. Arai, N. Shibata, T. Ohnuma, 2012, International journal of psychiatry in medicine.

Genetic Association between PLTP Gene Polymorphisms and Alzheimer’s Disease in a Japanese Population

H. Arai, N. Shibata, T. Ohnuma, 2010, Dementia and Geriatric Cognitive Disorders.

Supplementation with Matured Hop Bitter Acids Improves Cognitive Performance and Mood State in Healthy Older Adults with Subjective Cognitive Decline

H. Arai, Sumio Kondo, T. Ohnuma, 2020, Journal of Alzheimer's disease : JAD.

Genetic Association between Neurotrophin-3 Polymorphisms and Alzheimer's Disease in Japanese Patients

Shunichiro Shinagawa, Hisashi Yamada, H. Arai, 2013, Dementia and Geriatric Cognitive Disorders Extra.

High serum soluble tumor necrosis factor receptor 1 predicts poor treatment response in acute-stage schizophrenia

Yusuke Suzuki, Y. Tomino, H. Arai, 2017, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

Lack of Genetic Association of the UCHL1 Gene with Alzheimer’s Disease and Parkinson’s Disease with Dementia

N. Hattori, H. Arai, Y. Motoi, 2012, Dementia and Geriatric Cognitive Disorders.

No genetic association between Fyn kinase gene polymorphisms (−93A/G, IVS10+37T/C and Ex12+894T/G) and Japanese sporadic Alzheimer's disease

Tomoko Watanabe, H. Arai, A. Ueki, 2004, Neuroscience Letters.

High doses of antipsychotic polypharmacy are related to an increase in serum levels of pentosidine in patients with schizophrenia

Yusuke Suzuki, Y. Tomino, H. Arai, 2017, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

No genetic association between PCSK9 polymorphisms and Alzheimer's disease and plasma cholesterol level in Japanese patients.

Tomoko Watanabe, H. Arai, A. Ueki, 2005, Psychiatric genetics.

The effect of IL4 +33C/T polymorphism on risk of Japanese sporadic Alzheimer's disease

H. Baba, H. Arai, A. Ueki, 2002, Neuroscience Letters.

Changes in plasma glycine, l-serine, and d-serine levels in patients with schizophrenia as their clinical symptoms improve: Results from the Juntendo University Schizophrenia Projects (JUSP)

H. Arai, Toshihito Suzuki, N. Shibata, 2008, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

No Associations Found between PGBD1 and the Age of Onset in Japanese Patients Diagnosed with Sporadic Alzheimer's Disease

H. Arai, N. Shibata, T. Ohnuma, 2012, Dementia and Geriatric Cognitive Disorders Extra.

Corrigendum: Emerging roles of ARHGAP33 in intracellular trafficking of TrkB and pathophysiology of neuropsychiatric disorders

Masahiko Watanabe, M. Kano, T. Manabe, 2016, Nature Communications.

No genetic association between tryptophan hydroxylase 2 gene polymorphisms and Japanese schizophrenia.

H. Arai, N. Shibata, T. Ohnuma, 2007, Psychiatric genetics.

Increased plasma glutamate by antipsychotic medication and its relationship to glutaminase 1 and 2 genotypes in schizophrenia — Juntendo University Schizophrenia Projects (JUSP)

H. Baba, H. Arai, Toshihito Suzuki, 2007, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

Polymorphisms in the aldehyde dehydrogenase 2 and dopamine β hydroxylase genes are not associated with Alzheimer’s disease

H. Arai, N. Shibata, T. Ohnuma, 2014, Journal of Neural Transmission.

No genetic association between postsynaptic density-95 gene polymorphisms and schizophrenia

H. Arai, N. Shibata, T. Ohnuma, 2006, Neuroscience Letters.

Genetic Association between Akt1 Polymorphisms and Alzheimer's Disease in a Japanese Population

H. Baba, H. Arai, N. Shibata, 2011, International journal of Alzheimer's disease.

Genetic association between cytochrome P-450 2d6 gene polymorphism and plasma concentration of haloperidolin Japanese schizophrenics

H. Baba, H. Arai, N. Shibata, 1999 .

Genetic association between cytochrome P-450 2D6 gene polymorphism and plasma concentration of haloperidol in Japanese schizophrenics.

H. Baba, N. Shibata, H. Shimada, 1999, Psychiatric genetics.

Genetic Association between Presenilin 2 Polymorphisms and Alzheimer's Disease and Dementia of Lewy Body Type in a Japanese Population

N. Hattori, Shunichiro Shinagawa, Hisashi Yamada, 2016, Dementia and Geriatric Cognitive Disorders Extra.

Genetic association between RAGE polymorphisms and Alzheimer's disease and Lewy body dementia with in a Japanese population

Shunichiro Shinagawa, H. Arai, K. Nakayama, 2018 .

Genetic association between clusterin polymorphisms and Alzheimer's disease in a Japanese population

H. Baba, H. Arai, N. Shibata, 2011, Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society.

Visual and auditory hallucinations with excessive intake of paroxetine

H. Arai, T. Nagata, T. Ohnuma, 2003, Psychiatry and clinical neurosciences.

The Relationship Between the Response of Clinical Symptoms and Plasma Olanzapine Concentration, Based on Pharmacogenetics: Juntendo University Schizophrenia Projects (JUSP)

H. Arai, N. Shibata, T. Ohnuma, 2008, Therapeutic drug monitoring.

Case reports and literature review: The association between reactivation of human herpes virus-6 and peripheral white blood cell count in patients with carbamazepine-induced hypersensitivity syndrome

H. Arai, Toshihito Suzuki, M. Fukuta, 2006, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

Benefits of use, and tolerance of, medium-chain triglyceride medical food in the management of Japanese patients with Alzheimer’s disease: a prospective, open-label pilot study

T. Ohnuma, Aiko Toda, Yuto Takebayashi, 2016 .

Benefits of use, and tolerance of, medium-chain triglyceride medical food in the management of Japanese patients with Alzheimer’s disease: a prospective, open-label pilot study

H. Arai, N. Shibata, T. Ota, 2016, Clinical interventions in aging.

Corrigendum.

Masahiko Watanabe, T. Manabe, K. Ohi, 2019, European heart journal.

Associations of common copy number variants in glutathione S‐transferase mu 1 and D‐dopachrome tautomerase‐like protein genes with risk of schizophrenia in a Japanese population

H. Arai, N. Shibata, T. Ohnuma, 2015, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

Low‐dose lamotrigine augmentation therapy improves residual symptoms in treatment‐resistant schizophrenia: A report of five cases

H. Arai, N. Shibata, T. Ohnuma, 2013, Asia-Pacific psychiatry : official journal of the Pacific Rim College of Psychiatrists.

Shunichiro Shinagawa, Hisashi Yamada, H. Arai, 2013, Dementia and Geriatric Cognitive Disorders Extra.