G. Rappl

发表

Comparison of the enzymatic efficiency of Liberase TM and tumor dissociation enzyme: effect on the viability of cells digested from fresh and cryopreserved human ovarian cortex

E. Isachenko, V. Isachenko, P. Mallmann, 2018, Reproductive Biology and Endocrinology.

Construction of human artificial ovary from cryopreserved ovarian tissue: Appearance of apoptosis and necrosis after enzymatic isolation of follicles.

E. Isachenko, V. Isachenko, P. Mallmann, 2018, Cryobiology.

CD4+CD7− leukemic T cells from patients with Sézary syndrome are protected from galectin-1-triggered T cell death

S. Ugurel, U. Reinhold, J. Muche, 2002, Leukemia.

T cells that target carcinoembryonic antigen eradicate orthotopic pancreatic carcinomas without inducing autoimmune colitis in mice.

H. Abken, I. Schmidt-Wolf, A. Hombach, 2012, Gastroenterology.

Human CD4+ T Cells Lyse Target Cells via Granzyme/Perforin upon Circumvention of MHC Class II Restriction by an Antibody-Like Immunoreceptor1

H. Abken, H. Köhler, A. Hombach, 2006, The Journal of Immunology.

Regulatory T cells with reduced repressor capacities are extensively amplified in pulmonary sarcoid lesions and sustain granuloma formation.

B. Seliger, A. Schmidt, C. Grohé, 2011, Clinical immunology.

Dermal fibroblasts sustain proliferation of activated T cells via membrane-bound interleukin-15 upon long-term stimulation with tumor necrosis factor-alpha.

S. Ugurel, U. Reinhold, H. Abken, 2001, The Journal of investigative dermatology.

The CD3-Zeta Chimeric Antigen Receptor Overcomes TCR Hypo-Responsiveness of Human Terminal Late-Stage T Cells

H. Pfister, A. Schmidt, H. Abken, 2012, PloS one.

Visfatin/PBEF/Nampt and Resistin Expressions in Circulating Blood Monocytes are Differentially Related to Obesity and Type 2 Diabetes in Humans

J. Mauer, M. Laudes, W. Krone, 2010, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

Increased serum concentration of angiogenic factors in malignant melanoma patients correlates with tumor progression and survival.

S. Ugurel, U. Reinhold, W. Tilgen, 2001, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Increased S erum C oncentration o f A ngiogenic F actors i n Malignant M elanoma P atients C orrelates W ith T umor Progression a nd S urvival

S. Ugurel, U. Reinhold, W. Tilgen, 2001 .

Effective Proliferation of Human Regulatory T Cells Requires a Strong Costimulatory CD28 Signal That Cannot Be Substituted by IL-21

D. Kofler, H. Abken, A. Hombach, 2007, The Journal of Immunology.

Heterogenous susceptibility to CD95‐induced apoptosis in melanoma cells correlates with bcl‐2 and bcl‐x expression and is sensitive to modulation by interferon‐γ

S. Ugurel, U. Reinhold, W. Tilgen, 1999, International journal of cancer.

CD28 costimulation Impairs the efficacy of a redirected t-cell antitumor attack in the presence of regulatory t cells which can be overcome by preventing Lck activation.

A. Schmidt, D. Kofler, C. Wendtner, 2011, Molecular therapy : the journal of the American Society of Gene Therapy.

Upregulation of C4.4A expression during progression of melanoma.

U. Reinhold, M. Zöller, W. Tilgen, 2001, The Journal of investigative dermatology.

The CD7− subset of CD4+ memory T cells is prone to accelerated apoptosis that is prevented by interleukin-15 (IL-15)

S. Ugurel, U. Reinhold, H. Abken, 2001, Cell Death and Differentiation.

Accumulation of CD4+CD7− T cells in inflammatory skin lesions: evidence for preferential adhesion to vascular endothelial cells

U. Reinhold, H. Abken, W. Tilgen, 2000, Clinical and experimental immunology.

Ultraviolet light (UV)‐induced immunosuppression: Is vitamin D the missing link?

J. Reichrath, G. Rappl, 2003, Journal of cellular biochemistry.

A Proteomic View at T Cell Costimulation

B. Seliger, R. Lichtenfels, H. Abken, 2012, PloS one.

Noncanonical effector functions of the T-memory-like T-PLL cell are shaped by cooperative TCL1A and TCR signaling.

T. Aittokallio, D. Mougiakakos, M. Hallek, 2020, Blood.

Increased soluble CD95 (sFas/CD95) serum level correlates with poor prognosis in melanoma patients.

S. Ugurel, U. Reinhold, W. Tilgen, 2001, Clinical cancer research : an official journal of the American Association for Cancer Research.

CD4(+)CD7(-) T cells compose the dominant T-cell clone in the peripheral blood of patients with Sézary syndrome.

S. Ugurel, U. Reinhold, J. Muche, 2001, Journal of the American Academy of Dermatology.

Detection of tumor-associated circulating mRNA in serum, plasma and blood cells from patients with disseminated malignant melanoma.

S. Ugurel, U. Reinhold, W. Tilgen, 2001, Oncology reports.

Identification of a myofibroblast-specific expression signature in skin wounds.

J. Etich, H. Abken, B. Brachvogel, 2017, Matrix biology : journal of the International Society for Matrix Biology.

Temporal and tissue-specific requirements for T-lymphocyte IL-6 signalling in obesity-associated inflammation and insulin resistance

A. Waisman, J. Brüning, S. Theurich, 2017, Nature Communications.

Redirecting human CD4+CD25+ regulatory T cells from the peripheral blood with pre-defined target specificity

D. Kofler, H. Abken, A. Hombach, 2009, Gene Therapy.

Depletion of annexin A5, annexin A6, and collagen X causes no gross changes in matrix vesicle–mediated mineralization, but lack of collagen X affects hematopoiesis and the Th1/Th2 response

U. Schlötzer-Schrehardt, M. Paulsson, A. Niehoff, 2012, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

TCF/Lef1 activity controls establishment of diverse stem and progenitor cell compartments in mouse epidermis

G. Rappl, C. Niemann, S. John, 2011, The EMBO journal.

Calcyphosine-like (CAPSL) is regulated in Multiple Symmetric Lipomatosis and is involved in Adipogenesis

L. Prantl, M. Kye, J. Altmüller, 2019, Scientific Reports.

Non-canonical effector functions of the T-memory-like T-PLL cell are shaped by cooperative TCL1A and TCR signaling.

T. Aittokallio, D. Mougiakakos, M. Hallek, 2020, Blood.

The GPRC5A frameshift variant c.183del is not associated with increased breast cancer risk in BRCA1 mutation carriers

A. Meindl, R. Schmutzler, B. Burwinkel, 2019, International journal of cancer.

Antigen‐presenting human B cells are expanded in inflammatory conditions

M. Hallek, M. Herling, S. Theurich, 2017, Journal of leukocyte biology.

Blocking CD30 on T Cells by a Dual Specific CAR for CD30 and Colon Cancer Antigens Improves the CAR T Cell Response against CD30- Tumors.

H. Abken, A. Hombach, G. Rappl, 2019, Molecular therapy : the journal of the American Society of Gene Therapy.

Extracellular tyrosinase mRNA within apoptotic bodies is protected from degradation in human serum.

U. Reinhold, W. Tilgen, G. Rappl, 2001, Clinical chemistry.

Detection of Tumor‐Associated Circulating mRNA in Patients with Disseminated Malignant Melanoma

S. Ugurel, U. Reinhold, W. Tilgen, 2001, Annals of the New York Academy of Sciences.

Interlaboratory evaluation of a new reverse transcriptase polymerase chain reaction-based enzyme-linked immunosorbent assay for the detection of circulating melanoma cells: a multicenter study of the Dermatologic Cooperative Oncology Group.

S. Ugurel, A. Bosserhoff, U. Reinhold, 2001, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Facts and pitfalls in the detection of tyrosinase mRNA in the blood of melanoma patients by RT-PCR.

S. Ugurel, U. Reinhold, W. Tilgen, 2001, Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer.

Adoptive immunotherapy with redirected T cells produces CCR7- cells that are trapped in the periphery and benefit from combined CD28-OX40 costimulation.

H. Abken, A. Hombach, M. Chmielewski, 2013, Human gene therapy.

Mitofusin 2 is required to maintain mitochondrial coenzyme Q levels

C. Dieterich, T. Brandt, A. Galinier, 2015, The Journal of cell biology.

Extensive amplification of human regulatory T cells alters their functional capacities and targets them to the periphery.

A. Schmidt, H. Abken, C. Mauch, 2008, Rejuvenation research.

T cells redirected by a CD3ζ chimeric antigen receptor can establish self-antigen-specific tumour protection in the long term

H. Abken, A. Hombach, M. Chmielewski, 2012, Gene Therapy.

CD7(-) T cells are late memory cells generated from CD7(+) T cells.

J. Becker, A. Schmidt, D. Schrama, 2008, Rejuvenation research.

Role of LTBP4 in alveolarization, angiogenesis, and fibrosis in lungs.

A. Sterner-Kock, A. Schauss, C. Jüngst, 2017, American journal of physiology. Lung cellular and molecular physiology.

Role of LTBP-4 in alveolarization , angiogenesis and fibrosis in 1 lungs 2 Running title LTBP-4 in alveolarization , angiogenesis , fibrosis 3

A. Sterner-Kock, A. Schauss, C. Jüngst, 2017 .

Gene transfer into human cord blood-derived CD34(+) cells by adeno-associated viral vectors.

M. Hallek, M. Pesce, M. Capogrossi, 2010, Experimental hematology.

IL12 integrated into the CAR exodomain converts CD8+ T cells to poly-functional NK-like cells with superior killing of antigen-loss tumors

H. Abken, A. Sachinidis, A. Hombach, 2021, Molecular therapy : the journal of the American Society of Gene Therapy.

PECAM1+/Sca1+/CD38+ Vascular Cells Transform into Myofibroblast-Like Cells in Skin Wound Repair

M. Paulsson, J. Etich, H. Abken, 2013, PloS one.

No evidence of skin infection with Chlamydia pneumoniae in patients with cutaneous T cell lymphoma.

U. Reinhold, W. Sterry, W. Tilgen, 2003, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

Arming cytokine-induced killer cells with chimeric antigen receptors: CD28 outperforms combined CD28-OX40 "super-stimulation".

H. Abken, A. Hombach, G. Rappl, 2013, Molecular therapy : the journal of the American Society of Gene Therapy.

Adoptive immunotherapy with redirected T cells produces CCR7- cells that are trapped in the periphery and benefit from combined CD28-OX40 costimulation.

H. Abken, A. Hombach, M. Chmielewski, 2013, Human Gene Therapy.

Germline C1GALT1C1 mutation causes a multisystem chaperonopathy.

R. Cummings, L. Weber, J. Altmüller, 2023, Proceedings of the National Academy of Sciences of the United States of America.

Depletion of annexin A5, annexin A6, and collagen X causes no gross changes in matrix vesicle–mediated mineralization, but lack of collagen X affects hematopoiesis and the Th1/Th2 response

U. Schlötzer-Schrehardt, M. Paulsson, A. Niehoff, 2012, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.