M. Ohta

发表

Stimulatory Effect of Ethanol on Pancreatic Secretion in Conscious Rats Requires CCK-A Receptor

S. Kanai, A. Funakoshi, K. Miyasaka, 2005, Pancreas.

The effect of spironolactone pretreatment on digitoxin metabolism in isolated hepatocytes from male and female rats.

K. Kitani, Y. Sato, M. Ohta, 1982, Biochemical pharmacology.

The effect of idebenone on the lateral mobility of proteins in hepatocyte plasma membrane of old rats as revealed by fluorescence recovery after photobleaching (FRAP) technique using an endogenous label.

K. Kitani, I. Zs -Nagy, M. Ohta, 1990, Archives of gerontology and geriatrics.

Aging impairs release of central and peripheral cholecystokinin (CCK) in male but not in female rats.

A. Funakoshi, K. Miyasaka, M. Ohta, 1997, The journals of gerontology. Series A, Biological sciences and medical sciences.

Age-associated reduction of stimulatory effect of ghrelin on food intake in mice.

H. Uematsu, S. Kanai, K. Miyasaka, 2012, Archives of gerontology and geriatrics.

Lymphatic lipid transport is not impaired in ageing rat intestine

S. Kanai, Yuko Sato, A. Funakoshi, 2000, Mechanisms of Ageing and Development.

A peroxisome proliferator-activated receptor gamma agonist influenced daily profile of energy expenditure in genetically obese diabetic rats.

T. Shimazoe, Shigenori Watanabe, Y. Ichimaru, 2002, Japanese journal of pharmacology.

Age-associated gallstone formation in male and female CCK-1(A) receptor-deficient mice

S. Kanai, A. Funakoshi, H. Hosoya, 2007, Journal of Gastroenterology.

Susceptibility to obesity and gallbladder stasis produced by a protein- and fat-enriched diet in male mice compared with female mice

S. Kanai, A. Funakoshi, S. Takiguchi, 2007, Nutrition & metabolism.

Tauro α‐muricholate is as effective as tauro β‐muricholate and tauroursodeoxycholate in preventing taurochenodeoxycholate‐induced liver damage in the rat

K. Kitani, S. Kanai, Yuko Sato, 1994 .

Tauro beta-muricholate is as effective as tauroursodeoxycholate in preventing taurochenodeoxycholate-induced liver damage in the rat.

K. Kitani, S. Kanai, Y. Sato, 1990, Life sciences.

Differing transport maxima values for taurine-conjugated bile salts in rats and hamsters.

K. Kitani, S. Kanai, Y. Sato, 1986, The American journal of physiology.

The order of hepatic cytotoxicity of bile salts in vitro does not agree with that examined in vivo in rats.

K. Kitani, S. Kanai, M. Ohta, 1990, Life sciences.

Age and sex associated differences in the relative abundance of multiple species of cytochrome P-450 in rat liver microsomes. A separation by HPLC of hepatic microsomal cytochrome P-450 species.

M. Chiba, K. Kitani, M. Ohta, 1985, Biochemical pharmacology.

Chronic treatment of (-)deprenyl prolongs the life span of male Fischer 344 rats. Further evidence.

M. Carrillo, K. Kitani, S. Kanai, 1993, Life Science.

Lack of ghrelin secretion in response to fasting in cholecystokinin-A (-1), -B (-2) receptor-deficient mice.

H. Uematsu, S. Kanai, A. Funakoshi, 2006, The journal of physiological sciences : JPS.

Gastric acid secretion in cholecystokinin-1 receptor, -2 receptor, and -1, -2 receptor gene knockout mice

T. Matsui, S. Kanai, A. Funakoshi, 2008, The Journal of Physiological Sciences.

Enhanced gastric emptying of a liquid gastric load in mice lacking cholecystokinin-B receptor: a study of CCK-A,B, and AB receptor gene knockout mice

T. Noda, A. Nagata, T. Matsui, 2004, Journal of Gastroenterology.

Energy metabolism and turnover are increased in mice lacking the cholecystokinin-B receptor.

T. Noda, A. Nagata, T. Matsui, 2002, The Journal of nutrition.

Overexpression of Cholecystokinin-B/ Gastrin Receptor Gene in the Stomach of Naturally Occurring Cholecystokinin-A Receptor Gene Knockout Rats

S. Kanai, A. Funakoshi, K. Miyasaka, 1998, Digestion.

Absence of the cholecystokinin-A receptor deteriorates homeostasis of body temperature in response to changes in ambient temperature.

S. Nomoto, S. Kanai, A. Funakoshi, 2004, American journal of physiology. Regulatory, integrative and comparative physiology.

Lack of Cholecystokinin-A Receptor Enhanced Gallstone Formation: A Study in CCK-A Receptor Gene Knockout Mice

T. Noda, S. Kanai, A. Funakoshi, 2003, Digestive Diseases and Sciences.

Bitter melon malt vinegar increases daily energy turnover in rats.

M. Ichikawa, S. Kanai, A. Funakoshi, 2003, Journal of nutritional science and vitaminology.

Hepatic injury induced by bile salts: Correlation between biochemical and morphological events

K. Kitani, S. Kanai, Yuko Sato, 1990, Hepatology.

Morphological, physiological and biochemical alterations in livers of rodents induced by protease inhibitors: a comparison with old livers.

K. Kitani, S. Kanai, Y. Sato, 1989, Advances in experimental medicine and biology.

Lipofuscin-like substances accumulate rapidly in brain, retina and internal organs with cysteine protease inhibition.

K. Kitani, S. Kanai, Y. Sato, 1989, Advances in experimental medicine and biology.

Stimulatory effect of N-methyltyramine, a congener of beer, on pancreatic secretion in conscious rats.

E. Tsutsumi, Y. Suwa, S. Kanai, 2010, Alcoholism, clinical and experimental research.

STIMULATORY EFFECT OF N-METHYLTYRAMINE, A CONGENER OF BEER, ON PANCREATIC SECRETION IN CONSCIOUS RATS

S. Kanai, K. Miyasaka, M. Ohta, 2005 .

Orexin-A does not stimulate food intake in old rats.

H. Uematsu, S. Kanai, H. Hosoya, 2004, American journal of physiology. Gastrointestinal and liver physiology.

Association of ghrelin receptor gene polymorphism with bulimia nervosa in a Japanese population

S. Higuchi, S. Matsushita, A. Funakoshi, 2006, Journal of Neural Transmission.

Inhibitory Effect of Somatostatin on Cholecystokinin Release Is Independent of Luminal Cholecystokinin-Releasing Factor Content in Conscious Rats

S. Kanai, S. Suzuki, A. Funakoshi, 2001, Pancreas.

Carboxylester Lipase Gene Polymorphism as a Risk of Alcohol-induced Pancreatitis

S. Higuchi, Y. Tando, A. Funakoshi, 2005, Pancreas.

Isolation and characterization of a tumor-derived human protein related to chromogranin A and its in vitro conversion to human pancreastatin-48.

H. Tamamura, N. Fujii, H. Yajima, 1990, European journal of biochemistry.

Incidence of apoptosis in the pancreas of young and old rats.

Y. Sato, A. Funakoshi, K. Miyasaka, 1998, Archives of gerontology and geriatrics.

Retardation of Pancreatic Regeneration After Partial Pancreatectomy in a Strain of Rats Without CCK‐A Receptor Gene Expression

A. Funakoshi, K. Miyasaka, M. Ohta, 1997, Pancreas.

Role of Cholecystokinin (CCK)‐A Receptor for Pancreatic Growth After Weaning: A Study in a New Rat Model Without Gene Expression of the CCK‐A Receptor

S. Kanai, Yuko Sato, Y. Sato, 1996, Pancreas.

Inhibitory Effects of Octreotide on Luminal Cholecystokinin-releasing Factor, Plasma Cholecystokinin, and Pancreatic Secretion in Conscious Rats

S. Kanai, A. Funakoshi, K. Miyasaka, 2002, Pancreas.

Role of Cholecystokinin‐A (CCK‐A) Receptor in Pancreatic Regeneration After Pancreatic Duct Occlusion: A Study in Rats Lacking CCK‐A Receptor Gene Expression

A. Funakoshi, K. Miyasaka, M. Ohta, 1998, Pancreas.

Intraventricular infusion of leupeptin decreases Bmax of the D2 receptor in the striatum of young rats.

M. Asakura, K. Hasegawa, K. Kitani, 1992, Life sciences.

Differences in the influence of diet on Hepatic Glutathione S-transferase activity and glutathione content between young and old C57 black female mice

M. Carrillo, K. Kitani, S. Kanai, 1989, Mechanisms of Ageing and Development.

Leupeptin causes an accumulation of lipofuscin-like substances in liver cells of young rats

K. Kitani, S. Kanai, Yuko Sato, 1991, Mechanisms of Ageing and Development.

Impaired release of cholecystokinin (CCK) from synaptosomes in old rats

A. Funakoshi, K. Miyasaka, M. Ohta, 1995, Neuroscience Letters.

Gene expressions of cholecystokinin (CCK) and CCK receptors, and its satiety effect in young and old male rats.

A. Funakoshi, T. Kawanami, K. Miyasaka, 1995, Archives of gerontology and geriatrics.

Differences in ethanol ingestion between cholecystokinin-A receptor deficient and -B receptor deficient mice.

T. Matsui, S. Kanai, A. Funakoshi, 2005, Alcohol and alcoholism.

Identification of protein-bound riboflavin in rat hepatocyte plasma membrane as a source of autofluorescence.

I. Nagy, K. Kitani, M. Nokubo, 1989, Biochimica et biophysica acta.

Impaired Learning and Memory in OLETF Rats Without Cholecystokinin (CCK)-A Receptor

S. Nomoto, A. Funakoshi, K. Miyasaka, 1999, Physiology & Behavior.

Taurine conjugate of ursodeoxycholate plays a major role in the hepatoprotective effect against cholestasis induced by taurochenodeoxycholate in rats.

K. Kitani, S. Kanai, M. Ohta, 2008, Liver.

Different effects of oral administration of synthetic trypsin inhibitor on the pancreas between cholecystokinin-A receptor gene knockout mice and wild type mice.

T. Noda, S. Kanai, A. Funakoshi, 2002, Japanese journal of pharmacology.

DISCREPANCY BETWEEN PANCREATIC PROTEIN SECRETION AND CCK RELEASE IN RESPONSE TO BILE-PANCREATIC JUICE DIVERSION IN THE HYPERTROPHIED RAT PANCREAS INDUCED BY SYNTHETIC TRYPSIN INHIBITOR

S. Kanai, A. Funakoshi, K. Miyasaka, 2007 .

Sex difference in gene expressions of cholecystokinin (CCK) and CCK receptor in young and old rats.

A. Funakoshi, T. Kawanami, K. Miyasaka, 1995, Archives of gerontology and geriatrics.

Effect of long-term exercise under restricted-feeding on intestinal content of cholecystokinin and on the pancreas in aging rats.

M. Ichikawa, Y. Fujita, A. Funakoshi, 1994, Archives of gerontology and geriatrics.

Physical activity prevented age-related decline in energy metabolism in genetically obese and diabetic rats, but not in control rats

M. Ichikawa, S. Kanai, A. Funakoshi, 2003, Mechanisms of Ageing and Development.

Isolation and characterization of a tumor-derived human pancreastatin-related protein.

H. Tamamura, K. Tatemoto, H. Yajima, 1989, Biochemical and biophysical research communications.

Lack of satiety effect of cholecystokinin (CCK) in a new rat model not expressing the CCK-A receptor gene

S. Kanai, A. Funakoshi, T. Kawanami, 1994, Neuroscience Letters.

Mechanism of delayed gastric emptying in naturally occurring CCK-A receptor gene knockout (OLETF) rats.

Y. Sato, A. Funakoshi, K. Miyasaka, 2000, The Japanese journal of physiology.

A. Nagata, T. Matsui, Satoru Kobayashi, 2002, Neuroscience Letters.

High incidence of gallstone formation in CCK-A receptor gene knockout mice: Essential role of CCK-A receptor in gallstone formation

T. Noda, S. Kanai, Yuko Sato, 2001 .

Altered Energy Homeostasis and Resistance to Diet-Induced Obesity in KRAP-Deficient Mice

N. Kato, S. Shirasawa, T. Sasazuki, 2009, PloS one.

Increasing anticonvulsant effect of AD-810 (zonisamide) in aging BDF1 mice.

K. Kitani, S. Kanai, Y. Sato, 1987, Life sciences.

Decreased hydrogen-potassium-activated ATPase (H+-K+-ATPase) expression and gastric acid secretory capacity in aged mice.

S. Kanai, H. Hosoya, K. Miyasaka, 2007, Archives of gerontology and geriatrics.

Leupeptin Causes an Accumulation of Lipofuscin‐Like Substances and Other Signs of Aging in Kidneys of Young Rats: Further Evidence for the Protease Inhibitor Model of Aging a

K. Kitani, S. Kanai, Y. Sato, 1996, Annals of the New York Academy of Sciences.

Decline in glucose metabolism in the brain in neuronal ceroid lipofuscinosis (NCL) in English setter--evidence by positron emission tomography (PET).

M. Senda, H. Toyama, K. Kitani, 1995, Gerontology.

Disturbance of response to acute thermal pain in naturally occurring cholecystokinin-a receptor gene knockout Otsuka Long-Evans Tokushima Fatty (OLETF) rats.

T. Kaneko, S. Tahara, S. Nomoto, 2006, Journal of pharmacological sciences.

Decrease in exploratory behavior in naturally occurring cholecystokinin (CCK)-A receptor gene knockout rats

Satoru Kobayashi, A. Funakoshi, K. Miyasaka, 1996, Neuroscience Letters.

Tauroursodeoxycholate prevents biliary protein excretion induced by other bile salts in the rat.

K. Kitani, S. Kanai, M. Ohta, 1985, The American journal of physiology.

The effect of caloric restriction on the lateral diffusion constant of hepatocyte membrane proteins in C57BL/6 male mice of different ages: FRAP studies on liver smears

I. Zs.-Nagy, R. Cutler, K. Kitani, 1993, Mechanisms of Ageing and Development.

Age-estimations of rats based on the average lateral diffusion constant of hepatocyte membrane proteins as revealed by fluorescence recovery after photobleaching

K. Imahori, I. Zs.-Nagy, K. Kitani, 1986, Experimental Gerontology.

Alteration of plasma sex hormone levels associated with old age and its effect on hepatic drug metabolism in rats.

M. Chiba, S Fujita, K Kitani, 1990, The Journal of pharmacology and experimental therapeutics.

Age-dependent decrease in the hepatic uptake of taurocholic acid resembles that for ouabain. A possible role of surface membrane protein mobility.

K. Kitani, M. Ohta, Kenichi Kitani, 1990, Biochemical pharmacology.

Comparison of the lateral diffusion constant of hepatocyte membrane proteins in two wild mouse strains of considerably different longevity: FRAP studies on liver smears.

R. Cutler, I. Nagy, K. Kitani, 1993, Journal of Gerontology.

Effect of centrophenoxine and BCE-001 treatment on lateral diffusion of proteins in the hepatocyte plasma membrane as revealed by fluorescence recovery after photobleaching in rat liver smears

I. Zs.-Nagy, K. Kitani, M. Ohta, 1989, Experimental Gerontology.

Age-dependence of the lateral mobility of proteins in the plasma membrane of hepatocytes of C57BL/6 mice: FRAP studies on liver smears.

I. Zs.-Nagy, K. Kitani, M. Ohta, 1989, Journal of Gerontology.

Correlation between the biliary excretion of ouabain and the lateral mobility of hepatocyte plasma membrane proteins in the rat—the effects of age and spironolactone pretreatment

K. Kitani, S. Kanai, Yuko Sato, 1988, Hepatology.

Age-dependent decrease of the lateral diffusion constant of proteins in the plasma membrane of hepatocytes as revealed by fluorescence recovery after photobleaching in tissue smears.

K. Imahori, I. Zs.-Nagy, K. Kitani, 1986, Archives of gerontology and geriatrics.

Effect of leupeptin on the lateral mobility of proteins in the plasma membrane of hepatocytes of C57BL/6 mice: FRAP studies on liver smears.

K. Kitani, S. Kanai, Y. Sato, 1992, Archives of gerontology and geriatrics.

Possibilities and limitations of the smearing technique for cellular studies in compact tissues: a transmission electron microscopic analysis of liver smears.

K. Imahori, I. Zs.-Nagy, K. Kitani, 1988, Tissue & cell.

Age-dependent decrease in the hepatic uptake and biliary excretion of ouabain in rats.

K. Kitani, S. Kanai, Y. Sato, 1988, Biochemical pharmacology.

The mobility of concanavalin A receptors and surface immunoglobulins on rat hepatocyte plasma membranes.

G. Lustyik, K. Kitani, M. Ohta, 1987, Biochimica et biophysica acta.

Inhibitory effect of central calcitonin-gene related peptide (CGRP) on pancreatic secretion in conscious rats.

S. Suzuki, A. Funakoshi, K. Miyasaka, 2000, The Japanese journal of physiology.

Increased anticonvulsant effect of phenobarbital with age in mice--a possible pharmacological index for brain aging.

K. Kitani, S. Kanai, Y. Sato, 1985, Life Science.

U. Klotz, K. Kitani, S. Kanai, 1989, Archives of gerontology and geriatrics.

The neurotoxicity of phenobarbital and its effect in preventing pentylenetetrazole-induced maximal seizure in aging mice.

K. Kitani, S. Kanai, Y. Sato, 1988, Archives of gerontology and geriatrics.

The effect of age on the adaptation of the brain to the anticonvulsant effect of phenobarbital in mice.

K. Kitani, S. Kanai, Y. Sato, 1986, Life sciences.

Age-dependent increase in the threshold for pentylenetetrazole induced maximal seizure in mice.

K. Kitani, S. Kanai, Y. Sato, 1986, Life sciences.

K. Kitani, S. Kanai, Y. Sato, 1985, Life sciences.

Increased anticonvulsant effect of phenytoin in aging BDF1 mice.

K. Kitani, S. Kanai, Y. Sato, 1984, The Journal of pharmacology and experimental therapeutics.

Ursodeoxycholic acid reduces the systemic toxicity of 1,2-dichloro,4-nitrobenzene by stimulating hepatic glutathione S-transferase in mice.

K. Kitani, S. Kanai, Y. Sato, 1994, Life sciences.

Effect of perfringolysin O on the lateral diffusion constant of membrane proteins of hepatocytes as revealed by fluorescence recovery after photobleaching.

K. Imahori, I. Nagy, K. Kitani, 1988, Biochimica et biophysica acta.

Differences in the Appetite-Stimulating Effect of Orexin, Neuropeptide Y and Ghrelin among Young, Adult and Old Rats

S. Kanai, H. Hosoya, K. Miyasaka, 2006, Neuroendocrinology.

Characterization of the autofluorescence of rat liver plasma membranes.

M Nokubo, I Nagy, K Kitani, 1988, Biochimica et biophysica acta.

Metabolism of digitoxin by isolated rat hepatocytes.

K. Kitani, M. Nokubo, M. Ohta, 1980, Biochemical Pharmacology.

The digitoxin metabolism in isolated hepatocytes from young and old male Wistar rats.

K. Kitani, S. Kanai, Y. Sato, 1984, Archives of gerontology and geriatrics.

Tauro α‐muricholate is as effective as tauro β‐muricholate and tauroursodeoxycholate in preventing taurochenodeoxycholate‐induced liver damage in the rat

K. Kitani, S. Kanai, Yuko Sato, 1994 .

Overeating after restraint stress in cholecystokinin-a receptor-deficient mice.

T. Kaneko, S. Tahara, S. Kanai, 2005, The Japanese journal of physiology.

Tauro alpha-muricholate is as effective as tauro beta-muricholate and tauroursodeoxycholate in preventing taurochenodeoxycholate-induced liver damage in the rat.

K. Kitani, S. Kanai, Y. Sato, 1994, Hepatology.

Association of cholecystokinin-a receptor gene polymorphisms and panic disorder in japanese

S. Higuchi, H. Shimokata, O. Shirakawa, 2003 .

Stimulatory effect of N-methyltyramine, a congener of beer, on pancreatic secretion in conscious rats.

E. Tsutsumi, Y. Suwa, S. Kanai, 2010, Alcoholism, clinical and experimental research.

A peroxisome proliferator-activated receptor gamma agonist influenced daily profile of energy expenditure in genetically obese diabetic rats.

T. Shimazoe, Shigenori Watanabe, Y. Ichimaru, 2002, Japanese journal of pharmacology.