B. M. Baron

发表

Characterization of the novel 5-HT3 antagonists MDL 73147EF (dolasetron mesilate) and MDL 74156 in NG108-15 neuroblastoma x glioma cells.

M. Galvan, P. Boeijinga, B. M. Baron, 1992, European journal of pharmacology.

Excitatory amino acid antagonists

F. Salituro, B. Harrison, B. M. Baron, 1996 .

Activity of 5,7-dichlorokynurenic acid, a potent antagonist at the N-methyl-D-aspartate receptor-associated glycine binding site.

F. Salituro, B. Harrison, C. J. Schmidt, 1990, Molecular pharmacology.

Molecular cloning and functional expression of 5-HT1E-like rat and human 5-hydroxytryptamine receptor genes.

M. Erlander, J. Sutcliffe, T. Lovenberg, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Administration of a competitive NMDA antagonist MDL-100,453 reduces infarct size after permanent middle cerebral artery occlusion in rat

M. Chopp, N. Jiang, RuiLan Zhang, 1996, Journal of the Neurological Sciences.

Rapid down regulation of beta-adrenoceptors by co-administration of desipramine and fluoxetine.

J. Stegeman, A. Ogden, B. M. Baron, 1988, European journal of pharmacology.

The selectivity of MDL 74,721 in models of neurogenic versus vascular components of migraine.

E. Hamel, W. S. Lee, J. Elands, 1997, European journal of pharmacology.

[3H]MDL 105,519, a high-affinity radioligand for the N-methyl-D-aspartate receptor-associated glycine recognition site.

B. Harrison, R. Gross, B. M. Baron, 1996, The Journal of pharmacology and experimental therapeutics.

The Competitive NMDA Antagonist MDL‐100,453 Reduces Infarct Size After Experimental Stroke

M. Fisher, G. Metcalf, Y. Hasegawa, 1994, Stroke.

Activation of Gi protein by peptide structures of the muscarinic M2 receptor second intracellular loop.

B. A. Harris, S. McClue, B. M. Baron, 1994, European journal of pharmacology.

Binding of 5H-dibenzo[a,d]cycloheptene and dibenz[b,f]oxepin analogues of clozapine to dopamine and serotonin receptors.

P. Seeman, H. V. Van Tol, T. de Paulis, 1995, Journal of medicinal chemistry.

Human platelet phospholipase A2 activity is responsive in vitro to pH and Ca2+ variations which parallel those occurring after platelet activation in vivo

L. Limbird, B. M. Baron, 1988 .

Characterization of cell selectivity of two novel inhibitors of nitric oxide synthesis.

I. McDonald, J. F. French, B. M. Baron, 1992, European journal of pharmacology.

p-[125I]iodoclonidine, a novel radiolabeled agonist for studying central alpha 2-adrenergic receptors.

B. M. Baron, B. W. Siegel, 1990, Molecular pharmacology.

(R)-4-oxo-5-phosphononorvaline: a new competitive glutamate antagonist at the NMDA receptor complex.

H. White, I. McDonald, B. M. Baron, 1990, Journal of medicinal chemistry.

NMDA receptor complex antagonists have potential anxiolytic effects as measured with separation-induced ultrasonic vocalizations.

J. Kehne, B. Harrison, M. Palfreyman, 1991, European journal of pharmacology.

Competitive NMDA receptor antagonists; (R)-4-Oxo-5-phosphononorvaline structure-activity relationships

I. McDonald, B. M. Baron, J. Whitten, 1993 .

Synthesis of 3()-phosphonoacetyl-2()-piperidinecarboxylic acid, a conformationally-restricted glutamate antagonist

I. McDonald, R. Cube, B. M. Baron, 1991 .

Chemical Development of MDL 103371: An N-Methyl-d-Aspartate-Type Glycine Receptor Antagonist for the Treatment of Stroke†

B. Harrison, R. A. Farr, E. Huber, 2000 .

3-(2-Carboxyindol-3-yl)propionic acid-based antagonists of the N-methyl-D-aspartic acid receptor associated glycine binding site.

J. Kehne, F. Salituro, B. Harrison, 1992, Journal of medicinal chemistry.

CoMFA, synthesis, and pharmacological evaluation of (E)-3-(2-carboxy-2-arylvinyl)-4,6-dichloro-1H-indole-2-carboxylic acids: 3-[2-(3-aminophenyl)-2-carboxyvinyl]-4,6-dichloro-1H-indole-2-carboxylic acid, a potent selective glycine-site NMDA receptor antagonist.

B. Harrison, R. A. Farr, D. Friedrich, 2005, Journal of medicinal chemistry.

Competitive NMDA receptor antagonists: synthesis of β-ketophosphonate-substituted piperidine carboxylic acid derivatives

I. McDonald, R. Cube, B. M. Baron, 1993 .

2,4-Dihydro-3H-1,2,4-triazol-3-ones as anticonvulsant agents.

J. Kane, B. M. Baron, F. Miller, 1990, Journal of medicinal chemistry.

A novel adenylyl cyclase-activating serotonin receptor (5-HT7) implicated in the regulation of mammalian circadian rhythms

M. Erlander, J. Sutcliffe, T. Lovenberg, 1993, Neuron.

Pharmacological characterization of MDL 105,519, an NMDA receptor glycine site antagonist.

J. Kehne, F. Salituro, B. Harrison, 1997, European journal of pharmacology.

MDL 100,458 and MDL 102,288: two potent and selective glycine receptor antagonists with different functional profiles.

J. Kehne, F. Salituro, B. Harrison, 1995, European journal of pharmacology.

Nitric oxide synthesis in the CNS endothelium and macrophages differs in its sensitivity to inhibition by arginine analogues.

H. Cheng, I. McDonald, B. M. Baron, 1991, Life sciences.

Two members of a distinct subfamily of 5-hydroxytryptamine receptors differentially expressed in rat brain.

M. Erlander, J. Sutcliffe, T. Lovenberg, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Potent indole- and quinoline-containing N-methyl-D-aspartate antagonists acting at the strychnine-insensitive glycine binding site.

F. Salituro, B. Harrison, J. Turner, 1992, The Journal of pharmacology and experimental therapeutics.

Anticonvulsant activity of a novel NMDA/glycine site antagonist, MDL 104,653, against kindled and sound-induced seizures.

N. Dürmüller, B. Harrison, B. Meldrum, 1995, European journal of pharmacology.

α2‐Adrenergic and Muscarinic Cholinergic Receptors Have Oposing Actions on Cyclic AMP Levels in SK‐N‐SH Human Neuroblastoma Cells

B. M. Baron, B. W. Siegel, 1989 .

[3H]5,7-dichlorokynurenic acid, a novel radioligand labels NMDA receptor-associated glycine binding sites.

B. Harrison, M. Palfreyman, B. M. Baron, 1991, European journal of pharmacology.

4-[(Carboxymethyl)oxy]- and 4-[(carboxymethyl)amino]-5,7-dichloroquinoline-2-carboxylic acid: new antagonists of the strychnine-insensitive glycine binding site on the N-methyl-D-aspartate receptor complex.

B. Harrison, I. McDonald, B. M. Baron, 1990, Journal of medicinal chemistry.

Preclinical characterization of the potential of the putative atypical antipsychotic MDL 100,907 as a potent 5-HT2A antagonist with a favorable CNS safety profile.

J. Kehne, M. Poirot, R. Frank, 1996, The Journal of pharmacology and experimental therapeutics.

Activities of novel aryloxyalkylimidazolines on rat 5-HT2A and 5-HT2C receptors.

J. Freedman, B. M. Baron, B. W. Siegel, 1996, European journal of pharmacology.

Enzyme-activated antagonists of the strychnine-insensitive glycine/NMDA receptor.

R. Schwarcz, F. Salituro, P. Guidetti, 1994, Journal of medicinal chemistry.

Binding of 5H-dibenzo[b,e][1,4]diazepine and chiral 5H-dibenzo[a,d]cycloheptene analogues of clozapine to dopamine and serotonin receptors.

P. Seeman, H. V. Van Tol, H. Guan, 1994, Journal of medicinal chemistry.

Guanine nucleotides are competitive inhibitors of N-methyl-D-aspartate at its receptor site both in vitro and in vivo.

C. J. Schmidt, I. Reynolds, B. M. Baron, 1989, The Journal of pharmacology and experimental therapeutics.

Binding of the radiolabeled glycine site antagonist [3H]MDL 105,519 to homomeric NMDA-NR1a receptors.

K. Sreekrishna, K. Sreekrishna, B. M. Baron, 1996, European journal of pharmacology.

Human platelet phospholipase A2 activity is responsive in vitro to pH and Ca2+ variations which parallel those occurring after platelet activation in vivo.

L. Limbird, B. M. Baron, 1988, Biochimica et Biophysica Acta.

[3H] 5,7-dichlorokynurenic acid, a high affinity ligand for the NMDA receptor glycine regulatory site.

B. M. Baron, S. Hurt, 1991, Journal of receptor research.

Analysis of (R)-4-oxo-5-phosphononorvaline (MDL 100,453) in rat plasma and brain dialysate using liquid chromatography after derivatization with 6-aminoquinolyl-N-hydroxysuccinimidyl carbamate.

C. J. Schmidt, K. Haegele, B. M. Baron, 1995, Journal of pharmaceutical and biomedical analysis.

3-(2-carboxyindol-3-yl)propionic acid derivatives: antagonists of the strychnine-insensitive glycine receptor associated with the N-methyl-D-aspartate receptor complex.

F. Salituro, B. Harrison, I. McDonald, 1990, Journal of medicinal chemistry.