K. K. Roy

发表

Structural basis for the binding of a selective inverse agonist AF64394 with the human G-protein coupled receptor 3 (GPR3)

Bharathi, K. K. Roy, K. Roy, 2021, Journal of biomolecular structure & dynamics.

Novel, potent, orally bioavailable and selective mycobacterial ATP synthase inhibitors that demonstrated activity against both replicating and non-replicating M. tuberculosis.

A. Saxena, M. Y. Krishnan, S. Jaiswal, 2015, Bioorganic & medicinal chemistry.

Selective Cannabinoid 2 Receptor Stimulation Reduces Tubular Epithelial Cell Damage after Renal Ischemia-Reperfusion Injury

R. J. Doerksen, F. Park, B. Moore, 2018, The Journal of Pharmacology and Experimental Therapeutics.

Biological evaluation of novel substituted chloroquinolines targeting mycobacterial ATP synthase.

A. Saxena, Md. Sohail Akhtar, M. Y. Krishnan, 2013, International journal of antimicrobial agents.

Fragment-based design, docking, synthesis, biological evaluation and structure-activity relationships of 2-benzo/benzisothiazolimino-5-aryliden-4-thiazolidinones as cycloxygenase/lipoxygenase inhibitors.

V. Poroikov, A. Saxena, D. Filimonov, 2012, European journal of medicinal chemistry.

Emerging opportunities of exploiting mycobacterial electron transport chain pathway for drug-resistant tuberculosis drug discovery

M. A. Wani, K. K. Roy, M. Wani, 2019, Expert opinion on drug discovery.

Synthesis and Anti-Renal Fibrosis Activity of Conformationally Locked Truncated 2-Hexynyl-N6-Substituted-(N)-Methanocarba-nucleosides as A3 Adenosine Receptor Antagonists and Partial Agonists

Steven M. Moss, K. Jacobson, M. Cui, 2014, Journal of medicinal chemistry.

A systematic computational analysis of human matrix metalloproteinase 13 (MMP-13) crystal structures and structure-based identification of prospective drug candidates as MMP-13 inhibitors repurposable for osteoarthritis

K. K. Roy, Ravichandiran Velayutham, K. Satish Kumar, 2019, Journal of biomolecular structure & dynamics.

Structure investigation, enrichment analysis and structure-based repurposing of FDA-approved drugs as inhibitors of BET-BRD4

K. K. Roy, Ravichandiran Velayutham, Padmaja D. Wakchaure, 2018, Journal of biomolecular structure & dynamics.

HCV NS3 serine protease as a drug target for the development of drugs against hepatocellular carcinoma (liver cancer)

K. K. Roy, Ravichandiran Velayutham, Rishitha Gundala, 2020 .

In-silico studies for targeting PPARγ for the Type II Diabetes Mellitus

K. K. Roy, A. Garg, Sreya Gupta, 2022, Materials Today: Proceedings.

Novel Pyrimidinone Derivatives Show Anticancer Activity and Induce Apoptosis: Synthesis, SAR and Putative Binding Mode

Arnish Chakraborty, S. Mukherjee, S. Mondal, 2020 .

Emerging Roles and Potential Applications of Non-Coding RNAs in Cervical Cancer

S. Chauhan, Aishwarya Sharma, Anupam Singh, 2022, Genes.

Novel carbamates as orally active acetylcholinesterase inhibitors found to improve scopolamine-induced cognition impairment: pharmacophore-based virtual screening, synthesis, and pharmacology.

Aamir Nazir, Chandishwar Nath, A. Saxena, 2010, Journal of medicinal chemistry.

Antimalarial naphthoquinones. Synthesis via click chemistry, in vitro activity, docking to PfDHODH and SAR of lapachol-based compounds.

R. J. Doerksen, G. Brandão, K. K. Roy, 2018, European journal of medicinal chemistry.

Targeting the active sites of malarial proteases for antimalarial drug discovery: approaches, progress and challenges.

K. K. Roy, K. Roy, 2017, International journal of antimicrobial agents.

Negative allosteric modulators of cannabinoid receptor 2: protein modeling, binding site identification and molecular dynamics simulations in the presence of an orthosteric agonist

R. J. Doerksen, P. Pandey, K. K. Roy, 2020, Journal of biomolecular structure & dynamics.

Structure-Based Identification of Potent Natural Product Chemotypes as Cannabinoid Receptor 1 Inverse Agonists

R. J. Doerksen, S. Cutler, J. Rimoldi, 2018, Molecules.