B. Fennell

发表

An Ultra-specific Avian Antibody to Phosphorylated Tau Protein Reveals a Unique Mechanism for Phosphoepitope Recognition

H. Shih, Janet E. Paulsen, J. Bard, 2012, The Journal of Biological Chemistry.

Impacts of fast production of afucosylated antibodies and Fc mutants in ExpiCHO-S™ for enhancing FcγRIIIa binding and NK cell activation.

J. Chamberland, John J Scarcelli, Eric A Sousa, 2022, Journal of biotechnology.

Antimitotic herbicides bind to an unidentified site on malarial parasite tubulin and block development of liver-stage Plasmodium parasites.

A. Bell, M. Prudêncio, C. S. Gomes-Santos, 2013, Molecular and biochemical parasitology.

Discovery and multi-parametric optimization of a high-affinity antibody against interleukin-25 with neutralizing activity in a mouse model of skin inflammation

K. Nocka, P. Fallon, P. Walsh, 2022, Antibody therapeutics.

CDR-restricted engineering of native human scFvs creates highly stable and soluble bifunctional antibodies for subcutaneous delivery

Jason M. Edmonds, W. Somers, Janet E. Paulsen, 2013, mAbs.

Fundamental Characteristics of the Immunoglobulin VH Repertoire of Chickens in Comparison with Those of Humans, Mice, and Camelids

Janet E. Paulsen, L. Bloom, D. Gill, 2012, The Journal of Immunology.

Cellular and molecular actions of dinitroaniline and phosphorothioamidate herbicides on Plasmodium falciparum: tubulin as a specific antimalarial target.

Angus Bell, Enda Dempsey, A. Bell, 2006, Molecular and biochemical parasitology.

Effects of the antimitotic natural product dolastatin 10, and related peptides, on the human malarial parasite Plasmodium falciparum.

A. Bell, G. Pettit, B. Fennell, 2003, The Journal of antimicrobial chemotherapy.

Establishing in vitro in vivo correlations to screen monoclonal antibodies for physicochemical properties related to favorable human pharmacokinetics

James R. Apgar, Denise M O'Hara, S. Penn, 2018, mAbs.

Comprehensive interrogation of a minimalist synthetic CDR-H3 library and its ability to generate antibodies with therapeutic potential.

J. Glanville, Janet E. Paulsen, L. Bloom, 2013, Journal of molecular biology.

Isotype expression, post-translational modification and stage-dependent production of tubulins in erythrocytic Plasmodium falciparum.

A. Bell, B. Fennell, Z. A. Al-shatr, 2008, International journal for parasitology.

Affinity maturation of a humanized rat antibody for anti-RAGE therapy: comprehensive mutagenesis reveals a high level of mutational plasticity both inside and outside the complementarity-determining regions.

Janet E. Paulsen, S. Hufton, D. Gill, 2009, Journal of molecular biology.

A simple high-throughput purification method for hit identification in protein screening.

L. Bloom, D. Luxenberg, M. Whitters, 2008, Journal of immunological methods.

Dissection of the IgNAR V domain: molecular scanning and orthologue database mining define novel IgNAR hallmarks and affinity maturation mechanisms.

L. Wu, S. Hufton, M. Müller, 2010, Journal of molecular biology.

Augmented Binary Substitution: Single-pass CDR germ-lining and stabilization of therapeutic antibodies

James R. Apgar, Sue Townsend, Janet E. Paulsen, 2015, Proceedings of the National Academy of Sciences.

A Combination of Structural and Empirical Analyses Delineates the Key Contacts Mediating Stability and Affinity Increases in an Optimized Biotherapeutic Single-chain Fv (scFv)*

W. Somers, M. Stahl, W. Stochaj, 2015, The Journal of Biological Chemistry.